Full Publication List

  1. A. Mayer, G. Wagner, H. Uebelhack, H. Formanek, F. Parak, P. Schlecht and H. Eicher: Mössbauer studies on the electronic structure of ferrous iron in hemoglobin. Proc. of the 1st European Congress on Biophysics. Baden, Austria, Vol. VI, Y14 D9 (1971) (Abstract).

     

  2. A. Bundi, C. Grathwohl, J. Hochmann, R.M. Keller, G. Wagner and K. Wüthrich: Proton NMR of the Protected Tetrapeptides TFA-Gly-Gly-L-Ala-O-CH3, where X stands for one of the 20 common amino acids. J. Magn. Reson. 18, 191 (1975).

     

  3. K. Wüthrich and G. Wagner: NMR investigations of the dynamics of the aromatic amino acid residues in the basic pancreatic trypsin inhibitor. FEBS Lett. 50, 265-268 (1975).

     

  4. K. Wüthrich, J. Hochmann, R.M. Keller, G. Wagner, M. Brunori and G. Giacometti: 1H NMR relaxation in high spin ferrous hemoproteins. J. Magn. Reson. 19, 111 (1975).

     

  5. G. Wagner and K. Wüthrich: Proton NMR studies of the aromatic residues in the basic pancreatic trypsin inhibitor (BPTI). J. Magn. Reson. 20, 435 (1975).

     

  6. G. Wagner, A. DeMarco and K. Wüthrich: Convolution difference spectra at 360 MHz of the basic pancreatic trypsin inhibitor. J. Magn. Reson. 20, 565 (1975).

     

  7. K. Wüthrich and G. Wagner: High resolution NMR studies of the molecular dynamics of proteins in solution. Experientia 31, 726 (1975) (Abstract).

     

  8. L.R. Brown, A. DeMarco, G. Wagner and K. Wüthrich: A study of the lysyl residues in the basic pancreatic trypsin inhibitor using 1H NMR at 360 MHz. Eur. J. Biochem. 62, 103 (1976).

     

  9. G. Wagner and K. Wüthrich: 1H NMR studies of the dynamics of the solution conformation of the basic pancreatic trypsin inhibitor (BPTI). Proc. XXIII Coll.-Protides of the Biological Fluids. London: Pergamon Press, 186 (1976).

     

  10. K. Wüthrich, G. Wagner and H. Tschesche: Comparative 1H NMR studies of the cow colostrum trypsin inhibitor (CTI), the trypsin inhibitor of Helix pomatia (HPI) and the basic pancreatic trypsin inhibitor (BPTI). Proc. XXIII Coll.-Protides of the Biological Fluids. London: Pergamon Press, 201 (1976).

     

  11. G. Wagner, A. DeMarco and K. Wüthrich: Dynamics of the aromatic amino acid residues in the globular conformation of the basic pancreatic trypsin inhibitor (BPTI). I. 1H NMR studies. Biophys. Struct. Mechanism. 2, 139 (1976).

     

  12. K. Wüthrich, G. Wagner and A. DeMarco: NMR Studien der molekularen Dynamik von globulären Proteinen in Lösung: BPTI. Experientia 32, 802 (1977) (Abstract).

     

  13. G. Wagner, R. Richarz and K. Wüthrich: pH dependent changes of breathing modes in a globular protein. Experientia 33, 802 (1977) (Abstract).

     

  14. K. Wüthrich, G. Wagner, R. Richarz and A. DeMarco: Completion of X-ray structures of proteins by high resolution NMR. In "NMR in Biology" (R.A. Dwek, I.D. Campbell, R.E. Richards and R.J.P. Williams, eds.) Academic Press, London, 51 (1977).

     

  15. A. DeMarco, H. Tschesche, G. Wagner and K. Wüthrich: 1H NMR studies at 360 MHz of the methyl groups in native and chemically modified basic pancreatic trypsin inhibitor (BPTI). Biophys. Struct. Mechanism 3, 303 (1977).

     

  16. G. Wagner, K. Wüthrich and H. Tschesche: 1H NMR study of the conformation and the molecular dynamics of the glycoprotein cow colostrum trypsin inhibitor. Eur. J. Biochem. 86, 67-76 (1978).

     

  17. G. Wagner, K. Wüthrich and H. Tschesche: A 1H NMR study of the solution conformation of the isoinhibitor K from Helix pomatia. Eur. J. Biochem. 89, 367-377 (1978).

     

  18. L.R. Brown, A. DeMarco, R. Richarz, G. Wagner and K. Wüthrich: The influence of a single salt bridge on the static and dynamic features of the globular solution conformation of the basic pancreatic trypsin inhibitor: 1H and 13C NMR studies of the native and transaminated inhibitor. Eur. J. Biochem. 88, 87-95 (1978).

     

  19. K. Wüthrich, G. Wagner, R. Richarz and S.J. Perkins: Individual assignments of the methyl resonances in the 1H NMR spectrum of the basic pancreatic trypsin inhibitor (BPTI). Biochemistry 17, 2253-2263 (1978).

     

  20. K. Wüthrich and G. Wagner: Dynamic aspects of protein conformation studied by nuclear magnetic resonance techniques - Evidence for hydrophobic stability domains in globular proteins. Proc. Intern. Symp. on Biomolecular Structure, Conformation, Function and Evolution, Madras, 1978, (R. Srinivasan, ed.) Pergamon Press, Oxford, Vol. 2, 23 (1980).

     

  21. K. Wüthrich, G. Wagner and A. Bundi: NMR studies of molecular dynamics of peptides and proteins. In "Nuclear Magnetic Resonance Spectroscopy in Molecular Biology", Proceedings of the 11th Jerusalem Symposium on Quantum Chemistry and Biochemistry (B. Pullman, ed.) Reidel, Dodrecht, Holland, pp. 201-210 (1978).

     

  22. G. Wagner and K. Wüthrich: Dynamic model of globular protein conformations based on NMR studies in solution. Nature 275, 247-248 (1978).

     

  23. K. Wüthrich and G. Wagner: Internal motions in globular proteins. Trends in Biochemical Sciences 3, 227-230 (1978).

     

  24. K. Wüthrich, G. Wagner and R. Richarz: A dynamic model for globular protein conformations based on high resolution proton NMR data. In "Protein: Structure, Function and Industrial Applications". Proceedings of the 12th FEBS Meeting in Dresden (Hofmann et al., eds.), Pergamon Press, Oxford, England, 52, 143-152 (1979).

     

  25. A. Dubs, G. Wagner and K. Wüthrich: Individual assignments of amide proton resonances in the proton NMR spectrum of the basic pancreatic trypsin inhibitor. Biochim. Biophys. Acta 577, 177-194 (1979).

     

  26. G. Wagner and K. Wüthrich: Truncated driven nuclear overhauser effect (TOE). A new technique for studies of selective 1H-1H Overhauser effects in the presence of spin diffusion. J. Magn. Reson. 33, 675-680 (1979).

     

  27. G. Wagner, H. Tschesche and K. Wüthrich: The influence of a localized chemical modification of the basic pancreatic trypsin inhibitor on static and dynamic aspects of the molecular conformation in solution. Eur. J. Biochem. 95, 239-248 (1979).

     

  28. G. Wagner, A.J. Kalb and K. Wüthrich: Conformational studies by 1H NMR of the basic pancreatic trypsin inhibitor after reduction of the disulfide bond 14-38. Influence of charged protecting groups on the stability of the protein. Eur. J. Biochem. 95, 249-253 (1979).

     

  29. H. Roder, R. Richarz, G. Wagner and K. Wüthrich: NMR srudies of the reversible thermal denaturation of the basic pancreatic trypsin inhibitor. Experientia 35, 942 (1979) (Abstract).

     

  30. K. Wüthrich and G. Wagner: Nuclear magnetic resonance of labile protons in the basic pancreatic trypsin inhibitor. J. Mol. Biol. 130, 1-18 (1979).

     

  31. R. Richarz, P. Sehr, G. Wagner and K. Wüthrich: Kinetics of the exchange of individual amide protons in the basic pancreatic trypsin inhibitor. J. Mol. Biol. 130, 19-30 (1979).

     

  32. G. Wagner and K. Wüthrich: Correlation between the amide proton exchange rates and the denaturation temperature in globular proteins related to the basic pancreatic trypsin inhibitor. J. Mol. Biol. 130, 31-37 (1979).

     

  33. G. Wagner and K. Wüthrich: Structural interpretation of the amide proton exchange in the basic pancreatic trypsin inhibitor and related proteins. J. Mol. Biol. 134, 75-94 (1979).

     

  34. K. Wüthrich, H. Roder and G. Wagner: Internal Mobility and Unfolding of Globular Proteins. In "Protein Folding" (R. Jaenicke, ed.), Elsevier/North Holland Biomedical Press. 549-564 (1980).

     

  35. K. Wüthrich, G. Wagner, R. Richarz and W. Braun: Correlation between Internal Mobility and Stability of Globular Proteins. Biophysical J. 32, 549-560 (1980).

     

  36. G. Wagner: Activation Volumes ΔV‡ for the Rotational Flips of Internal Aromatic Rings in Globular Proteins, Determined by High Resolution 360 MHz 1H NMR at Variable Pressure. Experientia 36, 735 (1980) (Abstract).

     

  37. G. Wagner: Activation Volumes for the Rotational Motion of Interior Aromatic Rings in Globular Proteins Determined by High Resolution 1H NMR at Variable Pressure. FEBS Letters 112, 280-284 (1980).

     

  38. G. Wagner: A Novel Application of Nuclear Overhauser Enhancement (NOE) in Proteins: Analysis of Correlated Events in the Exchange of Internal Labile Protons. Biochem. Biophys. Res. Comm. 97, 614-620 (1980).

     

  39. K. Wüthrich, A. Eugster and G. Wagner: p2H Dependence of the Exchange with the Solvent of Interior Amide Protons in Basic Pancreatic Trypsin Inhibitor Modified by Reduction of the Disulfide Bond 14-38. J. Mol. Biol. 144, 601-604 (1980).

     

  40. A. Kumar, G. Wagner, R.R. Ernst and K. Wüthrich: Studies of J-Connectivities and Selective 1H -1H Overhauser Effects in H2O Solutions of Biological Macromolecules by Two-Dimensional NMR Experiments. Biochem. Biophys. Res. Comm. 96, 1156-1163 (1980).

     

  41. G. Wagner: Examples of Exchange Phenomena in the Basic Pancreatic Trypsin Inhibitor. In "Protein Dynamics and Energy Transduction", Proc. of the VIth Taniguchi International Symposium, Biophysics Division, Sanda, Japan (ed. S. Ishiwata), 56-82 (1980).

     

  42. G. Wagner, A. Kumar and K. Wüthrich: Systematic Application of Two-Dimensional 1H NMR Techniques for Studies of Proteins 2. Combined use of Correlated Spectroscopy and Nuclear Overhauser Spectroscopy for Sequential Assignments of Backbone Resonances and Elucidation of Secondary Structures. Eur. J. Biochem. 114, 375-384 (1981).

     

  43. A. Kumar, G. Wagner, R.R. Ernst and K. Wüthrich: Build-up Rates of the Nuclear Overhauser Effects Measured by Two-Dimensional Proton Magnetic Resonance Spectroscopy: Implications for Studies of Protein Conformation. J. Am. Chem. Soc. 103, 3654-3658 (1981).

     

  44. G. Wagner: Internal Mobility in Globular Proteins. Comments Mol. Cell. Biophys. 1, 261-280 (1982).

     

  45. K. Wüthrich, G. Wider, G. Wagner and W. Braun: Sequential Resonance Assignments as a Basis for Determination of Spatial Protein Structures by High Resolution Proton Nuclear Magnetic Resonance. J. Mol. Biol. 155, 311-319 (1982).

     

  46. G. Wagner and K. Wüthrich: Sequential Resonance Assignments in Protein 1H NMR Spectra: Basic Pancreatic Trypsin Inhibitor J. Mol. Biol. 155, 347-366 (1982).

     

  47. K. Wüthrich and G. Wagner: NMR Studies of Concerted Motions in the Interior and on the Surface of Globular Proteins. Proc. Ciba Foundation Symposium on Internal Motions in Proteins, London, 1982, pp. 310-328 (1982).

     

  48. G. Wagner and K. Wüthrich: Amide Proton Exchange and Surface Conformation of the Basic Pancreatic Trypsin Inhibitor (BPTI) in Solution: Studies with Two-Dimensional Nuclear Magnetic Resonance. J. Mol. Biol. 160, 343-361 (1982).

     

  49. G. Wagner and K. Wüthrich: Dynamik von Proteinstrukturen. Naturwissenschaften 70, 105-114 (1983).

     

  50. G. Wagner: Characterization of the distribution of internal motions in the basic pancreatic trypsin inhibitor using a large number of internal NMR probes. Quat. Rev. Biophys. 16, 1-57 (1983).

     

  51. G. Wagner, A. Pardi and K. Wüthrich: Hydrogen bond length and 1H NMR chemical shifts in proteins. J. Am. Chem. Soc. 105, 5948-5949 (1983).

     

  52. G. Wagner and E.R.P. Zuiderweg: Two-dimensional double quantum 1H NMR spectroscopy of proteins. Biochem. Biophys. Res. Comm. 113, 854-860 (1983).

     

  53. G. Wagner: Two-dimensional relayed coherence transfer spectroscopy of a protein. J. Magn. Reson. 55, 151-156 (1983).

     

  54. A. Pardi, G. Wagner and K. Wüthrich: Protein conformation and proton nuclear magnetic resonance chemical shifts. Eur. J. Biochem. 137, 445-454 (1983).

     

  55. M. Rance, O.W. S¿rensen, G. Bodenhausen, G. Wagner, R.R Ernst and K. Wüthrich: Improved spectral resolution in COSY 1H NMR spectra of proteins via double quantum filtering. Biochem. Biophys. Res. Comm. 117, 479-485 (1983).

     

  56. M. Rance, G. Wagner, O.W. S¿rensen, K. Wüthrich and R.R. Ernst: Application of ω1-decoupled 2D correlation spectra to the study of proteins. J. Magn. Reson. 59, 250-261 (1984).

     

  57. G. Wagner: 2D relayed coherence transfer-NOE spectroscopy (relayed NOESY). J. Magn. Reson. 57, 497-505 (1984).

     

  58. D. Neuhaus, G. Wider, G. Wagner and K. Wüthrich: X-relayed 1H -1H correlated spectroscopy. J. Magn. Reson. 57, 164-168 (1984).

     

  59. G. Wagner and K. Wüthrich: Observation of internal motility of proteins by nuclear magnetic resonance in solution. Methods in Enzymology, 131, 307-326 (1986)

     

  60. K. Wüthrich and G. Wagner: Internal dynamics in proteins.Trends Biochem. Sci. 9, 152-154 (1984).

     

  61. D. Neuhaus, G. Wagner, M. Vasak, J.H.R. Kägi and K. Wüthrich: 113Cd-1H spin-spin couplings in homonuclear 1H correlated spectroscopy of metallothionein. Identification of cysteine 1H spin systems. Eur. J. Biochem. 14, 659-667 (1984).

     

  62. C.I. Stassinopoulou, G. Wagner and K. Wüthrich: Two- dimensional 1H NMR of two chemically modified analogs of the basic pancreatic trypsin inhibitor. Sequence specific resonance resonance assignments and sequence location of conformation changes relative to the native protein. Eur. J. Biochem. 145, 423-430 (1984).

     

  63. G. Wagner, C.I. Stassinopoulou and K. Wüthrich: Amide proton exchange studies by two-dimensional correlated 1H NMR in two chemically modified analogs of the basic pancreatic trypsin inhibitor. Eur. J. Biochem. 145, 431- 436 (1984).

     

  64. G. Bodenhausen, G. Wagner, M. Rance, O.W. S¿rensen, K. Wüthrich and R.R. Ernst: Longitudinal two-spin order in 2D exchange spectroscopy (NOESY) J. Magn. Reson. 59, 542-550 (1984).

     

  65. M. Rance, G. Bodenhausen, G. Wagner, K. Wüthrich and R.R. Ernst: A systematic approach to the suppression of J cross- peaks in 2D exchange spectroscopy. J. Magn. Reson. 62, 497-510 (1985).

     

  66. H. Roder, G. Wagner and K. Wüthrich: Individual amide proton exchange rates in thermally unfolded basic pancreatic trypsin inhibitor. Biochemistry, 24, 7407-7411 (1985).

     

  67. H. Roder, G. Wagner and K. Wüthrich: Amide proton exchange in proteins by EX1 kinetics: Studies of the basic pancreatic trypsin inhibitor at various p2H and temperature. Biochemistry, 24, 7396-7407 (1985).

     

  68. W. Denk, G. Wagner and K. Wüthrich: Combined suppression of diagonal peaks and t1-ridges in two-dimensional nuclear Overhauser enhancement spectra. J. Magn. Reson. 62, 336- 340 (1985).

     

  69. G. Wagner, G. Bodenhausen, N. Müller, M. Rance, O.W. S¿rensen, R.R. Ernst and K. Wüthrich: Exchange of two-spin order in nuclear magnetic resonance: separation of exchange and cross relaxation processes. J. Am. Chem. Soc., 107, 6440-6446 (1985).

     

  70. D. Neuhaus, G. Wagner, M. Vasak, J.H.R. Kägi and K. Wüthrich: Systematic application of high resolution, phase sensitive two-dimensional 1H NMR techniques for the identification of the amino acid proton spin systems in proteins: rabbit liver metallothionein-2. Eur. J. Biochem., 151, 257-273 (1985).

     

  71. M.H. Frey, G. Wagner, M. Vasak, O.W. S¿rensen, D. Neuhaus, E. Wörgötter, J.H.R. Kägi and K. Wüthrich: Polypeptide-metal cluster connectivities in metallothionein-2 by novel 1H -113Cd heteronuclear two-dimensional NMR experiments. J. Am. Chem. Soc., 107, 6847-6851 (1985).

     

  72. W. Braun, G. Wagner, E. Wörgötter, M. Vasak, J.H.R. Kägi and K. Wüthrich: Polypeptide fold in the two meytal cluster of metallothionein-2 by nuclear magnetic resonance in solution J. Mol. Biol., 187, 125-129 (1986).

     

  73. G. Wagner, D. Neuhaus, E. Wörgötter, M. Vasak, J.H.R. Kägi and K. Wüthrich: Nuclear Magnetic Resonance identification of "half-turn" and 310-helix secondary structures in rabbit liver metallothionein-2. J. Mol. Biol., 187, 131-135 (1986).

     

  74. G. Wagner, D. Neuhaus, M. Vasak, E. Wörgötter, J.H.R. Kägi and K. Wüthrich: Sequence specific 1H NMR assignments in rabbit liver metallothionein-2. Eur. J. Biochem., 157, 275-289 (1986).

     

  75. G. Otting, H. Widmer, G. Wagner and K. Wüthrich: t1- and t2-ridges in 2D-NMR Spectra: Origin and Procedures for Suppression. J. Magn. Reson., 66, 187-193 (1986).

     

  76. W. Denk, R. Baumann and G. Wagner: Quantitative evaluation of cross peak intensities by projection of two-dimensional NOE spectra on a linear space spanned by a set of reference resonance lines. J. Magn. Reson., 67, 386-390 (1986).

     

  77. G. Wagner, M.H. Frey, D. Neuhaus, E. Wörgötter, W. Braun, M. Vasak, J.H.R. Kägi and K. Wüthrich: Spatial Structure of Rabbit Liver Metallothionein-2 in Solution by NMR. Proc. 2nd International Meeting on Metallothionein, Zürich, Aug. 1985, Birkhäuser Verlag, Basel, pp. 149-157.

     

  78. D. Brühwiler and G. Wagner: Selective Excitation of 1H resonances coupled to 13C : Heteronuclear COSY and RELAY experiments with 1H Detection. J. Magn. Reson., 69, 546-551 (1986).

     

  79. E. Wörgötter, G. Wagner and K. Wüthrich: Simplification of two-dimensional 1H NMR spectra using a X-filter. J. Am. Chem. Soc., 108, 6162-6167 (1986).

     

  80. G. Wagner and D. Brühwiler: Toward the complete assignment of the carbon Nuclear Magnetic Resonance spectrum of the basic pancreatic trypsin inhibitor. Biochemistry, 25, 5839-5843 (1986).

     

  81. G. Wagner, W. Braun, T. Havel, T. Schaumann, N. Go and K. Wüthrich: Protein Structures in Solution by Nuclear Magnetic Resonance and Distance Geometry. The Polypeptide Fold of the Basic Pancreatic Trypsin Inhibitor Determined using Two Different Algorithms, DISGEO and DISMAN.J. Mol. Biol.,196, 611-639 (1987).

     

  82. G. Otting, H. Senn, G. Wagner and K. Wüthrich: Editing of 2D 1H NMR spectra Using X Half-Filters: Combined Use with Residue Selective 15N-Labeling of Proteins. J. Magn. Reson., 70, 500-505 (1986).

     

  83. G. Wagner and K. Wüthrich: Reply to the Comments on "Amide Proton Exchange Studies by two-dimensional correlated 1H NMR in two chemically modified analoggs of the basic pancreatic trypsin inhibitor". Eur. J. Biochem. 157, 617-618 (1987).

     

  84. S.G. Hyberts, W. Märki and G. Wagner: Stereospecific assignments of side chain protons and characterization of torsion angles. Eur. J. Biochem. , 164, 625-635 (1987).

     

  85. W. Leupin, G. Wagner, W.A. Denny and K. Wüthrich: Assignment of the 13C nuclear magnetic resonance spectrum of a short DNA douplex with 1H detected two-dimensional heteronuclear correlation spectroscopy. Nucleic Acid Res. , 15, 267-275 (1987).

     

  86. G. Wagner, D. Brühwiler and K. Wüthrich: Reinvestigation of the aromatic side chains in the basic pancreatic trypsin inhibitor by heteronuclear two-dimensional nuclear magnetic resonance. J. Mol. Biol. 196, 227-231 (1987).

     

  87. M. Vasak, E. Wörgötter, G. Wagner, J.R.H. Kägi and K. Wüthrich: Metal coordination in rat liver metallothionein-2 prepared with or without reconstitution of the metal clusters and comparison with rabbit liver metallothionein. J. Mol. Biol., 196, 711-719 (1987).

     

  88. E. Wörgötter, G. Wagner, M. Vasak, J.H.R. Kägi and K. Wüthrich: Sequence specific 1H NMR assignments in rat liver metallothionein-2. Eur. J. Biochem. 167, 457-466 (1987).

     

  89. H. Widmer, G. Wagner, H. Schweitz, M. Lazdunski and K. Wüthrich: The secondary structure of the toxin ATX Ia from anemonia sulcata in aqueous solution determined on the basis of complete sequence specific 1H NMR assignments. Eur. J. Biochem. , 171, 177-192 (1988).

     

  90. E. Wörgötter, G. Wagner, M. Vasak, J.H.R. Kägi and K. Wüthrich: Heteronuclear filters for two-dimensional 1H NMR identification of the metal-bound amino acids in metallothionein and observation of small heteronuclear long-range couplings. J. Am. Chem. Soc., 110, 2388-2393 (1988).

     

  91. A. Arseniev, P. Schultze, E. Wörgötter, W. Braun, G. Wagner, M. Vasak, J.H.R. Kägi and K. Wüthrich: The three-dimensional structure of rabbit liver [Cd7]-metallothionein-2 in aqueous solution determined by nuclear magnetic resonance. J. Mol. Biol., 201, 637-657 (1988).

     

  92. P. Schultze, E. Wörgötter, W. Braun, G. Wagner, M. Vasak, J.H.R. Kägi and K. Wüthrich: The conformation of [Cd7]-metallothionein-2 from rat liver in aqueous solution determined by nuclear magnetic resonance. J. Mol. Biol., 203, 251-268 (1988).

     

  93. G. Wagner: Heteronuclear NMR experiments for studies of protein conformation. Methods in Enzymology, 176, 93-113 (1989).

     

  94. G. T. Montelione, M.E. Winkler, L.E. Bourton, E. Rinderknecht, M.B. Sporn and G. Wagner: Identification of two antiparallel β-sheet conformations in the solution structure of human recombinant type-α transforming growth factor by proton magnetic resonance, Proc. Natl. Acad. Sci., 86, 1519- 1523 (1989).

     

  95. N.R. Nirmala and G. Wagner: Measurements of 13C relaxation times in proteins by two-dimensional heteronuclear 1H-13C correlation spectroscopy, J. Am. Chem. Soc., 110, 7557-7558 (1988).

     

  96. S.G. Hyberts and G. Wagner: Taylor transformation of 2D NMR τm series from time dimension to polynomial dimension, J. Magn. Reson. , 81, 418-422 (1989).

     

  97. G. T. Montelione and G. Wagner: 2D chemical exchange NMR spectroscopy by proton detected heteronuclear correlation, J. Am. Chem. Soc., 111, 3096-3098 (1989).

     

  98. G. T. Montelione, M.E. Winkler, P. Rauenbuehler and G. Wagner: Accurate measurements of long-range heteronuclear coupling constants from homonuclear 2D NMR spectra of isotope-enriched proteins, J. Magn. Reson., 82, 198-204 (1989).

     

  99. N.R. Nirmala and G. Wagner: Measurement of 13C spin-spin relaxation times by two-dimensional heteronuclear 1H-13C correlation spectroscopy, J. Magn. Reson., 82, 659-661 (1989).

     

  100. G. Wagner and N.R. Nirmala: Measurements of Individual 13C Relaxation Times and Hydrogen Exchange Rates in Proteins by 2D NMR: Inferences for Interpretation of Structural Data. Chemica Scripta 29A, 27-30 (1989).

     

  101. G.T. Montelione and G. Wagner: Accurate Measurements of Homonuclear HN-Hα Coupling Constants in Polypeptides Using Heteronuclear 2D NMR Experiments. J. Am. Chem. Soc., 111, 5474-5475 (1989).

     

  102. G. Wagner, N.R. Nirmala, G.T. Montelione and S.G. Hyberts: Static and Dynamic Aspects of Protein Structure, Frontiers of NMR in Molecular Biology, UCLA Symposia on Molecular and Cellular Biology, New Series, Vol. 109, Editors, D. Live, I. Armitage and D. Patel, Alan R. Liss, Inc., New York, NY (1989), pp. 129-143.

     

  103. G. Wagner, S.G. Hyberts, D.W. Heinz and M.G. Grütter: NMR Characterization of Point Mutations on the Elastase Inhibitor Eglin c - Correlations with Functional Properties, in Structure & Methods, Vol. 2: DNA Complexes & Proteins, (Sarma & Sarma eds.), pp. 93-101, Adenine Press, Albany, New York, (1990).

     

  104. S.G. Hyberts and G. Wagner: Sequence-specific 1H NMR Assignments and Secondary Structure of Eglin c. Biochemistry, 29, 1465-1474 (1990).

     

  105. G.T. Montelione and G. Wagner: Triple Resonance Experiments For Establishing Conformation-Independent Sequential NMR Assignments in Isotope-Enriched Polypeptides., J. Magn. Reson., 87, 183-188 (1990).

     

  106. G.T. Montelione and G. Wagner: 1H-13C-15N Triple Resonance Experiments For Accurate Measurements of Homonuclear Coupling Constants in Proteins. Relaxation Times, 6, 2-3 (1989).

     

  107. G. Wagner: NMR Investigations of Protein Structure, Progress NMR Spectroscopy, 22, 101-139 (1990).

     

  108. D.J. Detlefsen, V. Thanabal, V.L. Pecoraro and G. Wagner: Sequential 1H NMR assignments of Fe(II) cytochrome c551 from Pseudomonas aeruginosa. Biochemistry, 29, 9377-9386 (1990).

     

  109. M. Adler and G. Wagner: Removal of Dispersive Baseline Distortions Caused by Strong Water Signals. J. Magn. Reson., 91, 450-454 (1991).

     

  110. J.W. Peng, V. Thanabal and G. Wagner: 2D Heteronuclear NMR Measurements of spin-lattice Relaxation times in the rotating frame of X nuclei in heteronuclear HX spin systems, J. Magn. Reson., 94, 82-100 (1991).

     

  111. G. Wagner, P. Schmieder and V. Thanabal: A new 1H-15N-13C triple resonance experiment for sequential assignments and measuring homonuclear Hα-HN vicinal coupling constants in polypeptides, J. Magn. Reson., 93, 436-440 (1991).

     

  112. M. Adler, R. Lazarus, M. Dennis and G. Wagner: Solution structure of kistrin a potent platelet aggregation inhibitor and integrin GPIIbIIIa antagonist, Science, 253, 445-448 (1991).

     

  113. R. T. Clubb, V. Thanabal, C. Osborne and G. Wagner: 1H and 15N Resonance Assignments of Oxidized Flavodoxin from Anacystis nidulans with 3D NMR, Biochemistry, 30, 7718-7730 (1991).

     

  114. B.J. Stockman, N.R. Nirmala, G. Wagner, T.D. Delcamp, M.T. DeYarman and J.H. Freisheim: Methotrexate binds in a non-productive orientation to human dihydrofolate reductase in solution based on NMR spectroscopy, FEBS Letters, 283, 267-269 (1991).

     

  115. P. Schmieder, V. Thanabal, L. P. Mcintosh, F.W. Dahlquist and G. Wagner: Measurements of Hα-HN vicinal coupling constants in a protein with large line widths using a new 3D 1H-15N-13C quadruple resonance NMR experiment, J. Am. Chem. Soc., 113, 6323-6324 (1991).

     

  116. J.W. Peng, V. Thanabal and G. Wagner: Improved Accuracy of Heteronuclear Transverse Relaxation Time Measurements in Macromolecules: Elimination of Antiphase Contributions, J. Magn. Reson., 95, 421-427 (1991).

     

  117. D.J. Detlefsen, V. Thanabal, V.L. Pecoraro and G. Wagner: Solution structure of Fe(II) cytochrome c551 from Pseudomonas aeruginosa as determined by 2D 1H-NMR, Biochemistry, 30, 9040-9046 (1991).

     

  118. J.W. Peng and G. Wagner: Mapping of Spectral Density Functions Using Heteronuclear NMR Relaxation Measurements, J. Magn. Reson., 98, 308-332 (1992).

     

  119. G.T. Montelione, K. Wüthrich, A.W. Burgess, E.C. Nice, G. Wagner, K.D. Gibson and H.A. Scheraga: Solution structure of murine epidermal growth factor determined by NMR spectroscopy and refined by energy minimization with restraints, Biochemistry, 31, 236-249 (1992).

     

  120. G. Wagner, V. Thanabal, B. J. Stockman, J. W. Peng, N. R. Nirmala, Sven G. Hyberts, Matthew S. Goldberg, David Detlefsen, Robert T. Clubb and Marc Adler: NMR Studies of Structure and Dynamics of Isotope Enriched Proteins, Biopolymers, 32, 381-390 (1992).

     

  121. B. J. Stockman, N. R. Nirmala, G. Wagner, Tavner J. Delcamp, Michael T. DeYarman and James, H. Freisheim: Sequence Specific 1H and 15N Resonance Assignments for Human Dihydrofolate Reductase in Solution, Biochemistry, 31, 218-229 (1992).

     

  122. M. Adler and G. Wagner: Sequential 1H NMR Assignments of Kistrin, a Potent Platelet Aggregation Inhibitor and Glycoprotein IIb-IIIa Antagonist, Biochemistry, 31, 1031-1039 (1992).

     

  123. G. Wagner: NMR as a tool for protein molecular design, Chemical Design Automation News, 6, 12-18 (1991).

     

  124. G. Wagner, S. G. Hyberts and T.F. Havel: NMR structure determination in solution: a critique and comparison with X-ray crystallography, Ann Rev. Biophys. Biomol. Struct. 21, 167- 198 (1992).

     

  125. R. T. Clubb, V. Thanabal, and G. Wagner: A New 3D HN(CA)HA experiment for obtaining fingerprint HN-Hα cross peaks in 15N and 13C labeled proteins, J. Biomol. NMR, 2, 203-210 (1992).

     

  126. R. T. Clubb, V. Thanabal, and G. Wagner: A Constant time three-dimensional triple resonance pulse scheme to correlate intraresidue HN, 15N and 13C' chemical shifts in 15N-13C labeled proteins, J. Magn. Reson., 97, 213-217 (1992).

     

  127. S.G. Hyberts, M.S. Goldberg, T.F. Havel and G. Wagner: The solution structure of eglin c based on measurements of many NOEs and coupling constants and its comparison with X-ray structures. Protein Science, 1, 736-751 (1992).

     

  128. J. D. Baleja, R. Marmorstein, S.C. Harrison and G. Wagner: Solution structure of the DNA-binding domain of Cd2-GAL4 from Saccaromyces cervisiae, Nature, 356, 450-453 (1992).

     

  129. D.W. Heinz, S.G. Hyberts, J.W. Peng, J.P. Priestle, G. Wagner and M. Grütter: Changing the inhibitory specificity and function of the proteinase inhibitor eglin c by site-directed mutagenesis: Functional and structural Investigation, Biochemistry, 31, 8755-8766 (1992).

     

  130. W. Braun, M. Vasak, A.H. Robbins, C.D. Stout, G. Wagner, J.H.R. Kägi and K. Wüthrich: Comparison of the X-ray Crystal Structure and the NMR solution structure of Rat metallothionein-2, Proc. Natl. Acad. Sci., USA, 89, 10124-10128 (1992). iconFull Text

     

  131. M.D. Reily, V. Thanabal, E.A. Lunney, J.T. Repline, C.C. Humblet and G. Wagner: Design, Synthesis and solution structure of a renin inhibitor. Structural constraints from NOE and homonuclear and heteronuclear coupling constants combined with distance geometry calculations. FEBS Letters, 302, 97-103 (1992).

     

  132. R. T. Clubb and G. Wagner: A triple resonance pulse scheme for selectively correlating amide 1HN and 15N nuclei with the Hα proton of the preceding residue, J. Biomol. NMR, 2, 389-394 (1992).

     

  133. J. W. Peng and G. Wagner: Mapping of Spectral Densities of N-H Bond Motions in Eglin c Using Heteronuclear Relaxation Experiments. Biochemistry, 31, 8571-8586 (1992).

     

  134. G. Wagner, S.G. Hyberts & J.W. Peng: Study of Protein Dynamics by NMR, in "NMR of Proteins" (Clore, G.M. & Gronenborn , A.M., eds.), Topics in Molecular and Structural Biology, MacMillan Press, 220-257 (1993).

     

  135. T. Mau, J. Baleja & G. Wagner: Effects of DNA Binding and Metal Substitution on the Dynamics of the Gal4 DNA Bindig Domain as Studied by Amide Proton Exchange. Protein Science, 1, 1403-1412 (1992).

     

  136. J.D. Baleja, V. Thanabal, T. Mau and G. Wagner: Solution structure of the DNA-binding domain of GAL4 from Saccharomyces cervisiae. Bull. Magn. Reson., 14, 175-180 (1992).

     

  137. M. Adler, P. Carter, R.A. Lazarus and G. Wagner: Cystein pairing in the glycoprotein IIbIIIa antagonist kistrin using NMR, chemical analysis and structure calculations. Biochemistry, 32, 282-289 (1993).

     

  138. K. Moffat and G. Wagner: Biophysical methods, editorial overview. Current Opinion in Structural Biology, 2, 803-804 (1992).

     

  139. R. T. Clubb, V. Thanabal, J. Fejzo, S.B. Ferguson, L. Zydowsky, C.H. Baker, C.T. Walsh and G. Wagner: Secondary structure and backbone resonance assignments of the periplasmic cyclophilin type peptidyl-prolyl isomerase from Escherichia coli. Biochemistry, 32, 6391-6401 (1993).

     

  140. J.W. Peng and G. Wagner: Investigation of protein motions via relaxation measurements. Methods in Enzymology, 239, 563-596 (1994).

     

  141. G. Wagner: Prospects of NMR for large proteins, J. Biol. NMR, 3, 375-385 (1993).

     

  142. P. Schmieder, A.S. Stern, G. Wagner and J.C. Hoch: Application of non-linear sampling schemes to COSY-type spectra. J. Biomol. NMR, 3, 569-576 (1993).

     

  143. J.W. Peng and G. Wagner: Protein Mobility from Multiple 15N Relaxation Parameters. In "NMR Probes of Molecular Dynamics", 373-454, R. Tycko, ed., Kluwer Academic Publishers (1994).

     

  144. L.E. Myers, A.E. Ferentz, M.P. Terranova, G. Wagner and G.L. Verdine: Repair of DNA methylphosphotriesters through a metalloactivated cysteine nucleophile. Science, 261, 1164-1167 (1993).

     

  145. L.E. Myers, G.L. Verdine and G. Wagner: Solution structure of the DNA methylphosphotriester repair domain of E.Coli ada. Biochemistry, 32, 14089-14094 (1993).

     

  146. D. F. Wyss, J. M. Withka, M. H. Knoppers, K. A. Sterne, M. A. Recny and G. Wagner: 1H Resonance Assignments and Secondary Structure of the 13.6 kDa Glycosylated Adhesion Domain of Human CD2. Biochemistry, 32, 10995-11006 (1993).

     

  147. J. Lee, J. Fejzo and G. Wagner: An inverted HSQC ω2 -half filtered NOESY with pulsed field gradients. J. Magn. Reson.Ser. B, 102, 322-325 (1993).

     

  148. G. Wagner: NMR relaxation and protein mobility. Current Opinion in Structural Biology, 3, 748-754 (1993).

     

  149. J.M. Withka, D.F. Wyss, G. Wagner, A.R.N. Arulanandam, E.L. Reinherz and M.A. Recny: Structure of the glycosylated adhesion domain of human T lymphocyte glycoprotein CD2. Structure, 1, 69-81 (1993).

     

  150. M.A. Markus, T. Nakayama, P. Matsudaira and G. Wagner: Solution structure of villin 14T, a domain conserved among actin-severing proteins. Protein Science, 3, 70-81 (1994).

     

  151. A.R.N. Arulanandam, J.M. Withka, D.F. Wyss, G. Wagner, A. Kister, M.A. Recny and E.L. Reinherz: The CD58 (LFA-3) binding site is a localized and highly charged surface area on the ACFCC'C" face of human CD2 domain 1. Proc. Nat. Acad. Sci. USA, 90, 11613-11617 (1993). icon Full Text

     

  152. R. T. Clubb, S. B. Ferguson, C. T. Walsh and G. Wagner: Three-Dimensional Solution Structure of Escherichia coli Periplasmic Cyclophilin. Biochemistry, 33, 2761-2772 (1994).

     

  153. P. Schmieder, A.S. Stern, G. Wagner and J.C. Hoch: Improved resolution in triple resonance spectra by non-linear sampling in the constant time domain.. J. Biomol. NMR, 4, 483-490 (1994).

     

  154. J. Fejzo, F.A. Etzkorn, R.T. Clubb, Y. Shi, C.T. Walsh and G. Wagner: The mutant E.coli F112W cyclophilin binds cyclosporin A in nearly identical conformation as human cyclophilin. Biochemistry, 33, 5711-5720 (1994).

     

  155. J. D. Baleja, T. Mau and G. Wagner: Recognition of DNA by GAL4 in solution: Use of a monomeric protein-DNA complex for study by NMR. Biochemistry, 33, 3071-3078 (1994).

     

  156. M.A. Markus, T. Nakayama, P. Matsudaira and G. Wagner: 1H, 15N, 13C and 13CO resonance asignments and secondary structure of villin 14T, a domain conserved among actin-severing proteins, J. Biomol. NMR, 4, 553-574 (1994).

     

  157. A. M. Krezel, G. Wagner, J. Seymour-Ulmer and R. Lazarus and Structure of the RGD protein decorsin: conserved motif and distinct function in leech proteins that affect blood clotting, Science, 264, 1944-1947 (1994).

     

  158. G. Wagner: Principles of Multidimensional NMR, in “NMR of Biological Macromolecules” (C. K. Stassinopoulou ed.), Proceedings of the NATO Advanced Study Institute, held at Kolympari, Crete, Springer-Verlag, Berlin pp. 17-36 (1994).

     

  159. G. Wagner: NMR of Proteins. Encyclopedia of Magnetic Resonance, 1, 680-682 (1995).

     

  160. A.R.N. Arulanandam, A. Kister, M.J. McGregor, D.F. Wyss, G. Wagner, and E.L. Reinherz: Interaction between CD2 and CD58 involves the major β sheet surface of each of their respective adhesion domains. J. Exp. Med.,180, 1861-1871 (1994).

     

  161. J.-X. Yang, A. Krezel, P. Schmieder, G. Wagner & T. F. Havel: An evaluation of least-squares fits to COSY spectra as a means of estimating proton-proton coupling constants. Part II Applications to polypeptides. J. Biomol. NMR, 4, 827-844 (1994).

     

  162. M. A. Markus, K.T. Dayie, P. Matsudaira and G. Wagner: Effect of deuteration on the amide proton relaxation rates in proteins: Heteronuclear NMR experiments on villin 14T. J. Magn. Reson.B, 105, 192-195 (1994).

     

  163. K.T. Dayie & G. Wagner: Relaxation-rate measurements for 15N-1H groups with pulsed-field gradients an preservation of coherence pathways. J. Magn. Reson., A 111, 121-126 (1994).

     

  164. L.C. Myers, T.D. Cushing, G. Wagner and G.L. Verdine: Metal-coordination sphere in the methylated ada protein/DNA co-complex. Chemistry & Biology, 1, 91-97 (1994).

     

  165. G. Wagner: Thin end of the wedge. Nature Str. Biol. 1, 497-498 (1994).

     

  166. E. Meiering & G. Wagner: Detection of tightly bound structural and functional water molecules in complexes of human dihydrofolate reductase with methotrexate and NADPH by NMR. J. Mol. Biol., 247, 294-308 (1995).

     

  167. E. M. Meiering, H. Li, T.J. Delcamp, J.H. Freisheim and G. Wagner, Roles of tryptophane-24 and Glutamate-30 in the tight binding of water molecules in the ternary complex of human dihydrofolate reductase with methotrexate and NADPH studied by site-directed mutagenesis and NMR spectroscopy. J. Mol. Biol., 247, 309-325 (1995).

     

  168. G. Wagner and D. Wyss: Cell surface adhesion receptors. Curr. Op. Str. Biol.,4, 841-851 (1994).

     

  169. D.F. Wyss, J. S. Choi and G. Wagner: Composition and sequence specific resonance assignments of the heterogeneous N-linked glycan in the 13.6 kDa adhesion domain of human CD2 as determined by NMR on the intact glycoprotein. Biochemistry, 34, 1622-1634 (1995).

     

  170. A.R.N. Arulanandam, J.M. Withka, D.F. Wyss, G. Wagner, A. Kister, P. Pallai, M.A. Recny and E.L. Reinherz: The CD58 (LFA-3) binding site is a localized and highly charged surface area on the ACFCC'C" face of human CD2 domain. In “Leucocyte typing V” Oxford University Press, Oxford, in press (1995).

     

  171. G. Wagner: Cadherin: A distant member of the immunoglobulin superfamily. Science, 267, 342 (1995).

     

  172. A. Krezel, C. Khasibhatla, P. Hidalgo, R. McKinnon and G. Wagner: Solution structure of the potassium channel inhibitor agitoxin 2: calipers for probing channel geometry. Protein Science, 4, 1478-1489 (1995).

     

  173. G. Wagner: The importance of being floppy. Nature Struct. Biol. 2, 255-257 (1995).

     

  174. J. Habazettl and G. Wagner: A new simplified method for analyzing nitrogen-15 nuclear magnetic relaxation data of proteins. J. Magn. Reson., B 109, 100-104 (1995).

     

  175. J. Habazettl, L. C. Myers, F. Yuan, G. L. Verdine and G. Wagner: Analysis of Backbone Dynamics, Amide Hydrogen Exchange, and Resonance Assignments of the DNA Methylphosphotriester Repair Domain of Escherichia coli Ada Using NMR. Biochemistry, 35, 9335-9348 (1996).

     

  176. P. Zhang, S. Talluri. H. Deng, D. Branton, G. Wagner: Solution structure of the pleckstring homology domain of Drosophila β-spectrin. Structure, 3, 1185-1195 (1995).

     

  177. D.F. Wyss J. S. Choi, J. Li, M. H. Knoppers, K. J. Willis, A. R. N. Arulanandam, A. Smolyar, E. L. Reinherz, G. Wagner:. CHO structure, Conformation and Function of the N-linked Glycan in the Adhesion Domain of Human CD2. Science, 269, 1273-1278 (1995).

     

  178. J. Chen, R. Peters, P. Saha, P. Lee, A. Theodoras, M. Pagano, G. Wagner and A. Dutta: A 39 amino acid domain of the cdk inhibitor p21 is sufficient to bind PCNA and block DNA replication. Nucleic Acid Res., 24, 1724-1733 (1996).

     

  179. V. Dötsch, R. E. Oswald and G. Wagner: Water suppression by coherence selection with absorptive lineshape without loss in sensitivity. J. Magn. Reson., B 108, 285-288 (1995).

     

  180. K.T. Dayie and G. Wagner: Carbonyl carbon relaxation rates reveal a dynamic heterogeneity of the polypeptide backbone in villin 14T, J. Magn. Reson., B 109, 105-108 (1995).

     

  181. G. Wagner, D.F. Wyss, J.S Choi, A. R. N. Arulanandam, E. L. Reinherz, and A. Krezel, R. A. Lazarus: NMR Studies of Proteins Involved in Cell Adhesion Processes, in "NMR as a structural tool for macromolecules: Current status and future directions", M.D. Kemple and B.D.N Rao, eds. Kluwer, New York, 1996.

     

  182. L.C. Myers, G. Wagner, G.L. Verdine: Direct Activation of the Methyl Chemosensor Protein N-Ada by CH3I. J. Am. Chem. Soc., 117, 10749-10750 (1995).

     

  183. J.W. Peng, G. Wagner: The Frequency Spectrum of NH Bonds in Eglin c From Spectral Density Mapping at Multiple Fields, Biochemistry, 34, 16733-16752 (1995).

     

  184. M.A. Markus, K. T. Dayie, P. Matsudaira, G. Wagner: Local mobility within villin 14T probed via heteronuclear relaxation measurements and a reduced spectral density mapping. Biochemistry, 35, 1722-1732 (1995).

     

  185. E. Kupce, G. Wagner: Wideband homonuclear decoupling in proteins. J. Magn. Reson., B 109, 329-333 (1995).

     

  186. G. Wagner, D.F. Wyss, J.S Choi, J. Li, A. Somlyar, A. R. N. Arulanandam, M.H. Knoppers, K.J. Willis and E. L. Reinherz: Conformation, mobility and function of the N-linked glycan in the adhesion domain of human CD2. in "Dynamics and the Problem of Recognition in Biological Macromolecules", O. Jardetzky and J.-F. Lefèvre, eds. Plenum Press, New York, 1996, pp. 257-266 (1996).

     

  187. V. Dötsch, R. E. Oswald and G. Wagner: Amino acid type selective triple resonance experiments. J. Magn. Reson., B 110, 107-111 (1996).

     

  188. H. Matsuo, H. Li and G. Wagner: A Sensitive HN(CA)CO Experiment for Deuterated Proteins. J. Magn. Reson., B 110, 112-115 (1996).

     

  189. K. Moffat and G. Wagner: Biophysical methods, editorial overview. Curr. Opin. Struct. Biol. 5, 637-639 (1995).

     

  190. J.-F Lefèvre, K. T. Dayie, J. W. Peng and G. Wagner: Internal Mobility in the Partially Folded DNA Binding and Dimerization Domains of GAL4: NMR Analysis of the N-H Spectral Density Functions. Biochemistry, 35, 2674-2686 (1996).

     

  191. V. Dötsch, R. E. Oswald and G. Wagner: Selective identification of threonine, valine and isoleucine sequential connectivities with a TVI-CBCACONH experiment. J. Magn. Reson., B 110, 304-308 (1996).

     

  192. K. T. Dayie, G. Wagner and J.-F. Lefèvre: Theory and Practice of Nuclear Spin Relaxation in Proteins, Ann Rev. Phys. Chem., 47, 243-282 (1996).

     

  193. K. T. Dayie, G. Wagner and J.-F. Lefèvre: Heteronuclear relaxation and the experimental determination of the spectral density function. in "Dynamics and the Problem of Recognition in Biological Macromolecules", O. Jardetzky and J.-F. Lefèvre, eds. Plenum Press, New York, 1996, pp. 139-162 (1996).

     

  194. E. Kupce, G. Wagner: Multi-site band-selective decoupling in proteins. J. Magn. Reson., B 110, 309-312 (1996).

     

  195. H. Matsuo, E. Kupce, H. Li and G. Wagner: Use of Selective Ca Pulses for Improvement of HN(CA)CO-D and HN(COCA)NH-D Experiments, J. Magn. Reson., B 111, 194-198 (1996).

     

  196. V. Dötsch and G. Wagner: Editing for amino acid type in CBCACONH experiments based on the 13Cβ-13Cγ coupling, J. Magn. Reson., B 111, 310-313 (1996).

     

  197. D. Wyss and G. Wagner: Structural role of sugars in glycoproteins. Curr. Opin. Biotechnology, 7, 409-416 (1996).

     

  198. V. Dötsch, H. Matsuo and G. Wagner: Amino acid type identification for deuterated proteins with a β-carbon edited HNCOCACB experiment. J. Magn. Reson., B 112, 95-100 (1996).

     

  199. S. Talluri and G. Wagner: An optimized 3D NOESY-HSQC, J. Magn. Reson., B 112, 200-205 (1996).

     

  200. H. Matsuo, E. Kupce, H. Li and G. Wagner: Increased sensitivity in HNCA and HN(CO)CA experiments by selective Cβ decoupling. J. Magn. Reson., B 113, 91-96 (1996).

     

  201. H. Matsuo, E. Kupce and G. Wagner: Resolution and Sensitivity Gain in HCCH-TOCSY Experiments by Homonuclear Cβ Decoupling. J. Magn. Reson., B 113, 190-194 (1996).

     

  202. E.L. Reinherz, J. Li, A. Smolyar, D.F. Wyss, M.H. Knoppers, K.J. Willis, A.R.N. Arulanandam, J.S. Choi, G. Wagner: CD2: An exception to the immunoglobulin superfamily concept. Science 273, 1242 (1996).

     

  203. K. J. Walters, H. Matsuo and G. Wagner: A simple method to distinguish intermonomer nuclear Overhauser effects in homodimeric proteins with C2 symmetry. J. Am. Chem. Soc., 119, 5958-5959 (1997).

     

  204. I. Najfeld, K.T. Dayie, G. Wagner, T.F. Havel: A robust method for estimating cross-relaxation rates from simultaneous fits to build-up and decay curves. J. Magn. Reson., 124, 372-382 (1997).

     

  205. S.A. Wolfe, P. Zhou, V. Dötsch, L. Chen, A. You, S. S. Ho, G.R. Crabtree, G. Wagner, G.L. Verdine: A novel Rel architecture in the DNA binding domain of human NFATc. Nature, 385, 172-176 (1997). icon Full Text

     

  206. D.F. Wyss, K.T. Dayie and G. Wagner: The counterreceptor binding site of human CD2 exhibits an extended surface patch with slow motions in the ms -μs range. Protein Science, 6, 534-542 (1997).

     

  207. J. Johnson, E. Meiering, J.l Wright, J.E. Pardo, A. Rosowsky and G. Wagner: NMR Solution Structures of the Antitumor Compound PT523 and NADPH in the Ternary Complex with Human Dihydrofolate Reductase. Biochemistry, 36, 4399-4411 (1997).

     

  208. P. Schmieder, A.S. Stern, G. Wagner, J. Hoch, Quantification of Maximum entropy spectrum reconstructions: J. Magn. Reson. 125, 332-339 (1997).

     

  209. M. A. Markus, P. Matsudaira and G. Wagner: Refined structure of villin 14T - Comparison with other actin-severing domains. Protein Science, 6, 1197-1209 (1997).

     

  210. K.T. Dayie and G. Wagner: Carbonyl Carbon Probe of Local Mobility in 13C,15N-Enriched Proteins Using High Resolution NMR. J. Am. Chem. Soc., 119, 7797-7806 (1997).

     

  211. P. Zhang, K.T. Dayie, G. Wagner: Unusual Lack of Internal Mobility And Fast Overall Tumbling in Oxidized Flavodoxin from Anacystis nidulans. J. Mol. Biol., 272, 443-455 (1997).

     

  212. J. L. Feltham, V. Dötsch, S. Raza, D. Manor, R. A. Cerione, M. J. Sutcliffe, G. Wagner, and R. E. Oswald: Definition of the Switch Surface in the Solution Structure of Cdc42Hs. Biochemistry, 36, 8755-8766 (1997).

     

  213. A.S. Carroll, D.E. Gilbert, X.Liu, J.W. Cheung, J. E. Michnowicz, G. Wagner, T.E. Ellenberger, T. K. Blackwell: SKN-1 domain and basic region monomer stabilization upon DNA binding. Genes and Development, 11, 2227-2238 (1997).

     

  214. K. Walters, K.T. Dayie, R. Reece, M. Ptashne, G. Wagner: Structure and mobility of the PUT3 Dimer. Nature Structural Biol., 4, 744-750 (1997).

     

  215. H. Matsuo, H. Li, A. M. McGuire, C. M. Fletcher, A.-C. Gingras, N. Sonenberg and G. Wagner: Structure of the translation factor eIF4E bound to m7GDP and interaction with 4E-binding protein. Nature Structural Biol., 4, 717-724 (1997).

     

  216. E. Kupce, H. Matsuo, G. Wagner: Homonuclear decoupling in proteins. In “Biological Magnetic Resonance, Volume 16: Modern Techniques in Protein NMR” (N.R. Krishna & L.J. Berliner, eds.), pp. 149-193 (1999).

     

  217. G. Wagner: An account of NMR in structural biology. Nature Structural Biol., 4, 841-844 (1997).

     

  218. C.M. Fletcher, A.M. McGuire, H. Li, H. Matsuo, A.-C. Gingras, N. Sonenberg, G. Wagner: 4E binding proteins inhibit the translation factor eIF4E without folded structure, Biochemistry, 37, 9-15 (1998).

     

  219. J.D. Baleja, V. Thanabal, G. Wagner: Refined solution structure of the DNA-binding domain of GAL4 and use of 3J(113Cd,1H) in structure determination. J. Biomol. NMR, 10, 397-401 (1997).

     

  220. A.E. Ferentz, T. Opperman, G.C. Walker, G. Wagner: Dimerization of the UmuD' protein in solution and its implications for regulation of SOS mutagenesis, Nature Structural Biol., 4, 979-983 (1997).

     

  221. P. Zhou, L.J. Sun, V. Dötsch, G. Wagner, G.L. Verdine: Structural Basis for signal integration by NFATc. Cell, 92, 687-696 (1998).

     

  222. A. M. McGuire, H. Matsuo, G. Wagner: Internal and overall motions of the translation factor eIF4E: Cap binding and insertion in a CHAPS detergent micelle, J. Biomol. NMR, 12, 73-88 (1998).

     

  223. S.E.Choe, P.T. Matsudaira, J. Osterhout, G. Wagner and E.I Shaknovich: Folding kinetics of villin 14T, a protein domain with a central β-sheet and two hydrophobic cores. Biochemistry, 37, 14508-14518 (1998).

     

  224. C.M. Fletcher, G. Wagner: The interaction of eIF4E with 4E-BP1 is an induced fit to a completely disordered protein. Protein Science, 7, 1639-1642 (1998).

     

  225. J. Zhu, F. Shibasaki, R. Price, J.-C. Guillemot, T. Yano, V. Dötsch, G. Wagner, P . Ferrara, F. McKeon: Intramolecular masking of nuclear import signal on NF-AT4 by casein kinase I and MEKK1. Cell, 93, 851-861 (1998).

     

  226. J.J. Chou, H. Matsuo, H. Duan, G. Wagner: Solution Structure of the RAIDD CARD Domain and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment, Cell, 94, 171-180 (1998).

     

  227. E. Kupce, P. Schmidt, M. Rance, G. Wagner: Adiabatic mixing in the liquid state: J. Magn. Reson., 135, 361-367 (1998).

     

  228. V. Dötsch, G. Wagner: New Approaches to Structure Determination by NMR, Curr. Opin. Struct. Biol., 8, 619-623 (1998).

     

  229. A. Jasanoff, G. Wagner, D.C. Wiley: Structure of a trimeric domain of the MHC class II-associated chaperonin and targeting protein Ii, EMBO J. 17, 6812-6818 (1998).

     

  230. K. Nishizawa, C. Freund, J. Li, G. Wagner, E.L. Reinherz: Identification of a novel proline-binding motif regulating CD2-triggered T-lymphocyte activation, Proc. Natl. Acad. Sci. 95, 14897-14902 (1998). icon Full Text

     

  231. G. Wagner, H. Matsuo, H. Li, C.M. Fletcher, A.M. McGuire, A.-C. Gingras, N. Sonenberg: Intermolecular interactions of proteins involved in the control of gene expression. in "Application of NMR to the Study of Structure and Dynamics of Supramolecular Chemistry", M. Pons (ed.), Kluwer Academic Publishers, Dordrecht, The Netherlands, pp. 247-254, 1999.

     

  232. B. J. Hare, D.F. Wyss, M. S. Osburne, P. S. Kern, E.L. Reinherz, G. Wagner: Structure, Specificity and CDR Mobility of a Class II Restricted Single-Chain T-cell Receptor. Nature Str. Biol., 6, 574-581 (1999). icon Full Text

     

  233. Z-Y. J. Sun, V. Dötsch, M. Kim, J. Li, E.L. Reinherz, G. Wagner: Functional glycan-free adhesion domain of human CD58: Design, production, and NMR structural studies, EMBO J., 18, 2941-2949 (1999).

     

  234. J. J. Chou, H. Li, G. S. Salvesen, J. Yuan, and G. Wagner Solution Structure of BID, an Intracellular Amplifier of Apoptotic Signaling, Cell, 96, 615-624 (1999).

     

  235. C. Freund, V. Dötsch, K. Nishizawa. E. Reinherz , G. Wagner: The GYF domain is a novel structural fold that is involved in lymphoid signaling through proline-rich sequences. Nature Str. Biol., 6, 656-660 (1999). icon Full Text

     

  236. C.M Fletcher, T.V. Pestova, C.U.T. Hellen, G. Wagner: Structure and interactions of the translation initiation factor eIF1, EMBO J., 18, 2631-2637 (1999).

     

  237. P.E.C.Hershey, J. Gross, S. McWhirter, T. Alber, G. Wagner, A.B. Sachs: The cap binding protein eIF4E induces folding of a functional domain of yeast translation initiation factor eIF4G1, J. Biol. Chem. 274, 21297-304 (1999).

     

  238. Y. Lin, C. M. Fletcher, J. Zhou, C. D. Allis, G. Wagner: Solution structure of the catalytic domain of Tetrahymena GCN5 histone acetyltransferase in complex with coenzyme A, Nature, 400, 86-89 (1999). icon Full Text

     

  239. J.-H. Wang, A. Smolyar, K. Tan, M. Kim, Z.-y. J. Sun, G. Wagner, E. L. Reinherz: Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counter receptors, Cell, 97, 791-803 (1999).

     

  240. K. J. Walters, G. T. Gasser, S. J. Lippard, G. Wagner: Structure of the soluble monooxygenase regulatory protein B. Proc. Natl. Acad. Sci., 96, 7877-7882 (1999). icon Full Text

     

  241. Y. Lin, G. Wagner: Efficient side-chain and backbone assignment in large proteins: Application to tGCN5, J. Biomol. NMR, 15, 227-239 (1999).

     

  242. F. del Río-Portilla, A. Gaskell, D. Gilbert, J.A.A. Ladias, G. Wagner: Solution structure of hRPABC14.4, an essential subunit of human RNA polymerases I, II and III, Nature Str. Biol., 6, 1039-1042 (1999). icon Full Text

     

  243. J. L. Battiste, T. V. Pestova, C. U. T. Hellen, G.Wagner: eIF1A Solution Structure Reveals a Large RNA-Binding Surface Important for Scanning Function, Mol. Cell, 5, 109-119 (2000).

     

  244. H. Matsuo, K. J. Walters, K. Teruya, T. Tanaka, G. T. Gasser, S. J. Lippard, Y. Kyogoku, G. Wagner: Identification by NMR of residues at contact surfaces in large, slowly exchanging complexes, J. Am. Chem Soc, 121, 9903-9904 (1999).

     

  245. B. J. Hare, G. Wagner: Application of automated NOE assignment to the three-dimensional structure refinement of a 28 kD single-chain T cell receptor. J. Biomol. NMR, 15, 103-113 (1999).

     

  246. H. Matsuo, T. Moriguchi, T. Takagi, T. Kusakabe, S. Buratowski, M. Sekine, Y. Kyogoku, G. Wagner: Efficient synthesis of 13C,15N labeled RNA containing the cap structure m7GpppA, J. Am. Chem Soc, 122, 2417-2421 (2000).

     

  247. X. Luo, G. Fang, M. Coldiron, Y. Lin, M.W. Kirschner, H. Yu and G. Wagner: Structure of the Mad2 spindle assembly checkpoint protein and analysis of its interaction with Cdc20, Nature Str. Biol., 7, 224-229 (2000). icon Full Text

     

  248. A. Jasanoff, S. Song, A.R. Dinner, G. Wagner, D.C. Wiley: One of two unstructured domains of Ii becomes ordered in complexes with MHC class II molecules. Immunity 10, 761-768 (1999).

     

  249. E.L. Reinherz, K. Tan, L. Tang, P. Kern, J.-h. Liu, Y. Xiong, R.E. Hussey, A. Smolyar, B. Hare, R. Zhang, A. Joachimiak, H.-C. Chang, G. Wagner, J.-h. Wang: The crystal structure of a CD4 lymphocyte-derived T-cell receptor in complex with peptide and MHC class II reveals an orthogonal docking mode. Science, 286, 1913-1921 (1999).

     

  250. P. Zhou, J. Chou, R. S. Olea, J. Yuan, G. Wagner: Solution structure of Apaf-1 CARD and its interaction with caspase-9 CARD: A structural basis for specific adaptor/caspase interaction. Proc. Natl. Acad. Sci., 96, 11265-11270 (1999). icon Full Text

     

  251. A. Kitao and G. Wagner: A space-time structure determination of human CD2 reveals the CD58-binding mode. Proc. Natl. Acad. Sci., 97, 2064-2068 (2000). icon Full Text

     

  252. A. A. Lugovskoy, P. Zhou, J. J. Chou, J. S. McCarty, Peng Li, G. Wagner: Solution structure of the CIDE-N-domain of CIDE-B and model for CIDE-N/CIDE-N interactions in DNA fragmentation pathways of apoptosis, Cell, 99, 747-755 (1999).

     

  253. J. L. Battiste, G. Wagner: Utilization of Site-Directed Spin Labeling and High Resolution Heteronuclear NMR for Global Fold Determination of Large Proteins with Limited NOE Data, Biochemistry, 39, 5355-5365 (2000).

     

  254. S.E.Choe, L. Li, P.T. Matsudaira, G. Wagner and E.I Shaknovich: Structure of the transition state for the folding of villin 14T, a protein domain with two hydrophobic cores. J. Mol. Biol. 304, 99-115 (2000).

     

  255. A.E. Ferentz, G. Wagner: NMR spectroscopy: A multifaceted approach to macromolecular structure. Quat. Rev. Biophys., 33, 29-65 (2000).

     

  256. P. Hidalgo, A. Z. Ansari, P. Schmidt, B. Hare, N. Simkovic, S. Farrell, E.J. Shin, M. Ptashne and Gerhard Wagner: Recruitment of the Transcriptional Machinery through GAL11P: Structure and Interactions of the GAL4 Dimerization Domain, Genes & Development, 15, 1007-1020 (2001).

     

  257. H. Kang, C. Freund, J.S. Duke-Cohan. A. Musacchio, G. Wagner, C.E. Rudd: SH3 domain recognition of a proline-independent tyorosine-based RKxxYxxY motif in immune cell adaptor SKAP55. EMBO J., 19, 2889-2899 (2000).

     

  258. A. Degterev, A. Lugovskoy, M. Cardone, B. Mulley, G. Wagner, T. Mitchison, J. Yuan. Identification of Small Molecule Inhibitors of BH3 and Bcl-xL interaction: Nature Cell Biology, 3, 173-182 (2001). icon Full Text

     

  259. K.S. Kim, Z.-Y.J. Sun, G. Wagner, E.L. Reinherz: Heterodimeric CD3εγ extracellular domain fragments: production, purification and structural anaysis, J. Mol. Biol. 302, 899-916 (2000).

     

  260. A. M. Krezel, J. S. Ulmer, G. Wagner, R.A. Lazarus: Recombinant decorsin: Dynamics of the RGD recognition site. Protein Sci. 9, 1428-1438 (2000).

     

  261. Y. Lin, V. Dötsch, T. Wintner, K. Peariso, L. C. Myers, J. E. Penner-Hahn, G. L. Verdine, G. Wagner: Structural Basis for the Functional Switch of the E. Coli Ada Protein, Biochemistry, 40, 4261-4271 (2001).

     

  262. P. Zhou, A. Lugovskoy, G. Wagner: A Solubility-Enhancement Tag (SET) for NMR Studies of Poorly Behaving Proteins. J. Biomol. NMR, 20, 11-14 (2001).

     

  263. P. Zhou, A. A. Lugovskoy, J. S. McCarty, Peng Li, G. Wagner: Solution Structure of DFF40 and DFF45 N-terminal Domain Complex and Mutual Chaperone Activity of DFF40 and DFF45. Proc. Natl. Acad. Sci., 98, 6051-6055 (2001). icon Full Text

     

  264. D.P. Goldenberg, R.E. Kohn, D.E. Gilbert, G. Wagner: Solution structure and backbone dynamics of an w-conotoxin precursor. Protein Science, 10, 538-550 (2001).

     

  265. J. L. Battiste, J. D. Gross, G. Wagner: Global fold determination of large proteins using site-directed spin labeling. . In “Biological Magnetic Resonance, Volume 17: Modern Techniques in Protein NMR” (N.R. Krishna & L.J. Berliner, eds.), 20, 79-101 (2003).

     

  266. A. E. Ferentz, G. C. Walker and G. Wagner: Converting a DNA checkpoint effector (UmuD2C) into a lesion bypass polymerase (UmuD'2C), EMBO Journal, 20, 4287-4298 (2001).

     

  267. Z.-Y.J. Sun, K.S. Kim, G. Wagner, E.L. Reinherz: Mechanisms Contributing to T Cell Receptor Signaling and Assembly Revealed by the Solution Structure of an Ectodomain Fragment of the CD3εγ Heterodimer, Cell, 105, 913-923 (2001).

     

  268. K. J. Walters, A. E. Ferentz, B. J. Hare, P. Hidalgo, A. Jasanoff, H. Matsuo, G. Wagner: Experimental Approaches for Characterizing Protein-Protein Complexes and Oligomers by NMR Spectroscopy. In Methods in Enzymology , Nuclear Magnetic Resonance of Biological Macromolecules (eds. T.L. James, V. Dötsch, U. Schmitz) , 339B, 238-258 (2001).

     

  269. C. Fan, H. Wang, S. Sun, G. Wagner, G. Li: Electron transfer reactivity and enzymatic activity of hemoglobin in a SP sephadex membrane. Anal. Chem., 73, 2850-2854 (2001).

     

  270. C. Fan, G. Li, G. Wagner: Effect of Dimethyl Sulfoxide on the Electron Transfer Reactivity of Hemoglobin. Bioelectrochemistry, 54, 49-51 (2001).

     

  271. C. Fan, Q. Gao, G. Li, D. Zhu, G. Wagner:An Unmediated Hydrogen Peroxide Biosensor Based on Hemoglobin Incorporated in a Montmorillonite Membrane. The Analyst, 126, 1086-1089 (2001).

     

  272. C. Fan, H. Wang, G. Li, D. Zhu, G. Wagner: Incorporation of Horseradish Peroxidase in a Kieselguhr Membrane and the application to a Mediator-free Hydrogen Peroxide Sensor. Anal. Sci. 17, 273-276 (2001).

     

  273. C. H. Lin, B. Hare, G. Wagner, S. C. Harrison, T. Maniatis, E. Fraenkel: Structure and function of IBiD, a newly identified domain of CBP/p300. Molecular Cell 8, 581-590 (2001).

     

  274. M. Kim , Z. Y. Sun , O. Byron , G. Campbell , G. Wagner , J.-h.Wang , E. L. Reinherz: Molecular dissection of the CD2-CD58 counter-receptor interface identifies CD2 Tyr86 and CD58 Lys34 residues as the functional "hot spot". J. Mol. Biol. 312, 711-720 (2001).

     

  275. A. A. Lugovskoy, A. I. Degterev, A. F. Fahmy, P. Zhou, J. D. Gross, J. Yuan, G. Wagner: A novel approach for characterizing protein ligand complexes: molecular basis for specificity of small-molecule Bcl-2 inhibitors, J. Am. Chem. Soc., 124, 1234-1240 (2002).

     

  276. A. Fahmy, G. Wagner: TreeDock: A Tool for Protein Docking Based on Minimizing van der Waals Energies, J. Am. Chem. Soc., 124, 1241-1250 (2002).

     

  277. K. J. Walters, M. F. Kleijnen, A. M. Goh, G. Wagner and P. M. Howley: Structural studies of the interaction between ubiquitin family proteins and the proteasome subunit S5a. Biochemistry, 41, 1767-1777 (2002).

     

  278. J. Müller, A. A. Lugovskoy, G. Wagner, S. J. Lippard: NMR Structure of the [2Fe–2S] Ferredoxin Domain from Soluble Methane Monooxygenase Reductase and the Interaction with its Hydroxylase, Biochemistry, 41, 42-51 (2002).

     

  279. G. Wagner, Z.-Y. J. Sun, P. Zhou, A. Lugovskoy, B. Hare, S. Endo, M. Kim. J.-h. Wang, E. L. Reinherz: How to trick proteins to behave well for structural studies - protein interactions in T-cell activation and apoptosis. In "Protein Structure, Dynamics, Genomics and Function", D. Moras and J. Puglisi, eds., in press.

     

  280. J. D. Gross, H. Matsuo, M. Fletcher, A. B. Sachs, G. Wagner: Interactions of the Eukaryotic Translation Initiation Factor eIF4E. Cold Spring Harbor Symposium on Quantitative Biology: The Ribosome, B. Stillman and D.J. Stewart, eds, Vol 66, 2001, pp. 397-402.

     

  281. P. Dormitzer, Z.-Y. J. Sun, G. Wagner, S. C. Harrison: The Rhesus Rotavirus VP4 Sialic Acid Binding Domain has a Galectin Fold with a Novel Carbohydrate Binding Site, EMBO J.. 21, 885-897 (2002).

     

  282. C. He, L. J. Sun, P. Zhou, D. P. G. Norman, V. Dötsch, J. D. Gross, W. S. Lane, G. Wagner,G. L. Verdine: A Zinc-Mediated Electrostatic Switch Controls the Adaptive Response of E.coli to Methylating Agents, submitted.

     

  283. S. J. Freedman, Z.-Y. J. Sun, F. Poy, A. L. Kung, D. M. Livingston, G. Wagner, M. J. Eck: Structural Basis for Recruitment of p300/CBP by Transcription Factor HIF-1, Proc. Natl. Acad. Sci. USA. 99, 5367-5372 (2002). icon Full Text

     

  284. P. Dormitzer, Z.-Y. J. Sun, O. Blixt, J. C. Paulson, G. Wagner, S. C. Harrison: The specificity of sialic acid binding by the rotavirus VP8* core, J. Virology, 76, 10512-10517 (2002).

     

  285. C. Freund, R. Kühne, H. Yang, E. L. Reinherz, Gerhard Wagner: Dynamic interaction of CD2 with the GYF and the SH3 domain of compartmentalized effector molecules, EMBO J., 21, 5985-5995 (2002).

     

  286. J.D. Gross, V.M. Gelev, G. Wagner: A sensitive and robust method for obtaining intermolecular NOEs between side chains in large proteins, J. Biomol. NMR, 25, 235- 242 (2003).

     

  287. D. Rovnyak, C. Filip, B. Itin, A.S. Stern, G. Wagner, R.G. Griffin, J.C. Hoch: Multiple quantum magic-angle spinning spectroscopy using non-linear sampling, J. Magn. Reson., 161, 43-55 (2003).

     

  288. K. J. Walters, A. M. Goh, Q. Wang, G. Wagner, P.M. Howley, Ubiquitin family proteins and their relationship to the proteasome: a structural perspective, Biochemica et Biophysica Acta-Molecular Cell Research, 1695, 73-87 (2004).

     

  289. A. Marintchev, V. G. Kolupaeva, T. V. Pestova, G. Wagner: Mapping the binding interface between human eIF1A and eIF5B – a new interaction between old partners, Proc. Natl. Acad. Sci. USA, 100, 1535-1540 (2003). icon Full Text

     

  290. J.D. Gross, N.J. Moerke, T. Von der Haar, A. A. Lugovskoy, A.B. Sachs, J. McCarthy, and G. Wagner: Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E. Cell, 115, 739-750 (2003).

     

  291. S.G. Hyberts, G. Wagner: IBIS – A tool for automated sequential assignment of protein spectra from triple resonance experiments, J. Biomol. NMR, 26, 335-344 (2003).

     

  292. M. H. A. Roehrl, S. G. Hyberts, Z.-Y. J. Sun, A. P. Fields, G. Wagner: Rapid backbone 1H, 13C, and 15N assignment of the V1 domain of human PKC iota using the new program IBIS, J. Biomol. NMR, 26, 373-374 (2003).

     

  293. M. Kato, T. Ito, G. Wagner, C. C. Richardson, T. Ellenberger: Modular Architecture of the Bacteriophage T7 Primase Couples RNA Primer Synthesis to DNA Synthesis, Mol. Cell, 11, 1349-1360 (2003).

     

  294. S. J. Freedman, Z.-Y. J. Sun, A. L. Kung, D. S. France, G. Wagner, M. J. Eck: Structural basis for negative regulation of hypoxia inducible factor-1α by CITED2, Nature Struct. Biol. 10, 504-512 (2003). icon Full Text

     

  295. C. Freund R. Kühne, S. Park, K. Thiemke E. L. Reinherz, G. Wagner: Structural investigations of a GYF domain covalently linked to a proline-rich peptide, J. Biomol. NMR, 27, 143-149 (2003).

     

  296. P. Kim Z.-Y. J. Sun, S. C. Blacklow, G. Wagner, M.J. Eck: A Zinc Clasp Structure Tethers Lck to T-cell Coreceptors CD4 and CD8, Science, 301, 1725-1728 (2003).

     

  297. A. E. Bennett, J.D. Gross, G. Wagner: Broadband 13C-13C Adiabatic Mixing in Solution Optimized for High Fields, J. Magn. Reson., 165, 59-79 (2003).

     

  298. O. Gozani, P. Karuman, D. R. Jones, D. Ivanov, J. Cha, A. A. Lugovskoy, C. L. Baird, H. Zhu, S.F. Field, J. Villasenor, B. Mehrotra, J. Chen, V. R. Rao, J. S. Brugge, C. G. Ferguson, B. Payrastre, D. G. Myszka, L. C. Cantley, G. Wagner, N. Dievecha, G. D. Prestwich, J. Yuan: The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor, Cell, 114, 99-111 (2003).

     

  299. T. Ito, G. Wagner: Effective methods for obtaining mammalian protein samples for NMR studies: Codon optimization, chaperone co-expression, and rational mutagenesis, J.Biomol. NMR, 28, 357-367 (2004).

     

  300. S. Misaghi, Z.-Y. J. Sun, P. Stern, R. Gaudet, G. Wagner, H. Ploegh: A Structural and Functional Analysis of the Human Cytomegalovirus US3 Protein, J. Virology, 78, 413-23 (2004).

     

  301. M. H. A. Roehrl, S. Kang, J. Aramburu, A. Rao, G. Wagner , P. G Hogan: Selective inhibition of calcineurin-NFAT signaling by blocking protein-protein interaction with small organic molecules, PNAS, 101, 7554-7559 (2004).

     

  302. I. B. Lomakin, V. G. Kolupaeva, A. Marintchev, G. Wagner, T.V. Pestova : Position of eukaryotic initiation factor eIF1 on the 40S ribosomal subunit determined by directed hydroxyl radical probing, Genes & Development, 17, 2786-2797 (2003).

     

  303. D. Rovnyak, J.C. Hoch, A.S. Stern, G. Wagner: Resolution and Sensitivity of High Field Nuclear Magnetic Resonance Spectroscopy, J. Biomol. NMR, 30, 1-10 (2004).

     

  304. G. Wagner. NMR studies on the basic pancreatic trypsin inhibitor. Magn. Reson. Chem. 41, S3-S15, 2003.

     

  305. A. Natarajan, N. Moerke, Y.-H. Fan, H. Chen, W. J. Christ, G. Wagner , J. A. Halperin . Bioorg. Med. Chem. Lett., 14, 2657-2660.

     

  306. Z.-Y. J. Sun, S. G. Hyberts, D. Rovnyak, A. S. Stern, J. C. Hoch, G. Wagner: Rapid NMR Side-Chain Assignments with Reduced-Dimensionality HC(CO)NH and Non-Uniform Sampling, in press.

     

  307. T. von der Haar, J. D. Gross, G. Wagner, J. E. G. McCarthy: Physical properties of the cap-binding protein eIF4E and their relation to its function in vivo, Nature Structural and Molecular Biology, 11, 503-511 (2004).

     

  308. T. Ito, A. Marintchev, G. Wagner: Solution structure of the alpha subunit of human eukaryotic initiation factor 2 reveals structural similarity to the guanine-nucleotide exchange factor eEF1B, Structure, 12, 1693-1704 (2004). 

     

  309. D. Rovnyak, D. Frueh, M. Sastry, Z.-Y. J. Sun, S. , J.C. Hoch, A.S. Stern, G. Wagner : Accelerated Acquisition of High Resolution Triple-Resonance Spectra Using Non-Uniform Sampling and Maximum Entropy Reconstruction , J. Magn. Reson., 170, 15-21 (2004).

     

  310. Z.-Y. J. Sun, G. Wagner: 3D structure determination by NMR, in “Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine”, P. Schmieder and H. Oschkinat, eds., Springer Verlag, Heidelberg, 2004.

     

  311. M. Kato, T. Ito, G. Wagner, T. Ellenberger: A molecular handoff between bacteriophage T7 DNA primase and T7 DNA polymerase initiates DNA synthesis. J Biol Chem, 279, 30554-30562 (2004).

     

  312. L. D. Walensky, A. L. Kung, I. Escher, T. J. Malia, S. Barbuto,1 R. Wright, G. Wagner, G. L. Verdine, S. J. Korsmeyer: Activation of Apoptosis In Vivo by a Hydrocarbon-Stapled BH3 Helix, Science, 305, 1466-1470 (2004).

     

  313. L.L. Chatwood, J. Müller, J.D. Gross, G. Wagner, S.J. Lippard: NMR structure of the flavin domain from soluble methane monooxygenase. Biochemistry, 43, 11983-11991 (2004).

     

  314. D. Ivanov, J. R. Stone, J. L. Maki, T. Collins, G. Wagner: Mammalian SCAN domain dimer is a domain-swapped homologue of the HIV capsid C-terminal domain, Mol. Cell, 17, 137-143 (2005)).

     

  315. M. H. A. Roehrl , J. Y. Wang, G. Wagner: A General Framework for Development and Data Analysis of Competitive High-Throughput Screens for Small-Molecule Inhibitors of Protein-Protein Interactions by Fluorescence Polarization, Biochemistry,43, 16056-16066 (2004)s.

     

  316. M. H. A. Roehrl , J. Y. Wang, G. Wagner : Discovery of Small-Molecule Inhibitors of the NFAT-Calcineurin Interaction by Competitive High-Throughput Fluorescence Polarization Screening, Biochemistry, 43, 16067-16075 (2004).

     

  317. Z.-Y. J. Sun, S. T. Kim, I. C. Kim, A. Fahmy, E. L. Reinherz, G. Wagner: Solution Structure Of The Cd3εδ Ectodomain Fragment And Comparison With Cd3εγ As A Basis For Modeling T Cell Receptor Topology And Signaling , PNAS, 101, 16867-16872 (2004).

     

  318. D. P. Frueh, T. Ito, J.-S. Li, G. Wagner, S. Glaser, N. Khaneja: Sensitivity Enhancement in NMR of Macromolecules by Application of Optimal Control Theory, J. Magn. Reson., in press.

     

  319. S. Park, R. Isaacson, H. T. Kim, P. A. Silver, G. Wagner: Ufd1 exhibits the AAA-ATPase fold with two distinct ubiquitin interaction sites , submitted.

     

  320. A. A. Lugovskoy, A. I. Degterev, A. F. Fahmy, P. Zhou, J. D. Gross, J. Yuan, G. Wagner: A novel approach for characterizing protein ligand complexes: molecular basis for specificity of small-molecule Bcl-2 inhibitors, J. Am. Chem. Soc., 124, 1234-1240 (2002).  Full Text

     

  321. T. Ito, G. Wagner: Effective methods for obtaining mammalian protein samples for NMR studies: Codon optimization, chaperone co-expression, and rational mutagenesis, J.Biomol. NMR, 28, 357-367 (2004). icon Full Text

     

  322. M. H. A. Roehrl , J. Y. Wang, G. Wagner: A General Framework for Development and Data Analysis of Competitive High-Throughput Screens for Small-Molecule Inhibitors of Protein-Protein Interactions by Fluorescence Polarization, Biochemistry, 43, 16056-16066 (2004). icon Full Text

     

  323. D. P. Frueh, T. Ito, J.-S. Li, G. Wagner, S. Glaser, N. Khaneja: Sensitivity Enhancement in NMR of Macromolecules by Application of Optimal Control Theory, J. Biomol. NMR, 32, 23-30 (2005). icon Full Text

     

  324. Z.-Y. J. Sun, S. G. Hyberts, D. Rovnyak, S. Park, A. S. Stern, J. C. Hoch, G. Wagner: High-resolution aliphatic side-chain assignments in 3D HCcoNH experiments with joint H-C evolution and non-uniform sampling. J. Biomol. NMR, 32, 55-60 (2005). icon Full Text

     

  325. Z.-Y. J. Sun, D. P. Frueh, P. Selenko, J. C. Hoch, G. Wagner: Fast Assignment of 15N-HSQC Peaks using High-Resolution 3D HNcocaNH Experiments with Non-Uniform Sampling, J. Biomol. NMR, 33, 43-50 (2005). icon Full Text

     

  326. D. P. Frueh, D. A. Vosburg, C.T. Walsh, G. Wagner: Determination of all nOes in 1H-13C-Me-ILV-U-2H-15N proteins with two time-shared experiments, J. Biomol. NMR, 34, 31–40 (2006). icon Full Text

     

  327. D. P. Frueh, Z.Y. J. Sun, D. A. Vosburg, C.T. Walsh, G. Wagner: Non-uniformly sampled double-TROSY hNcaNH experiments for sequential assignments of large proteins, J. Am. Chem. Soc., 128, 5757-5763 (2006). icon Full Text

     

  328. M. Reibarkh, T. Malia, G. Wagner: Measurement of protein-ligand NOEs in the limit of intermediate exchange, J. Biomol.NMR, in press (2006b).

     

  329. C. He, J.-C. Hus, L. J. Sun, P. Zhou, D. P. G. Norman, V. Dötsch, H. Wei, J. D. Gross, W. S. Lane, G. Wagner, G. L. Verdine: A Methylation-dependent Electrostatic Switch Controls DNA repair and Transcriptional Activation by E. coli Ada, Mol Cell, 20, 117-129 (2005). icon Full Text