Full Publication List

 

1. A. Mayer, G. Wagner, H. Uebelhack, H. Formanek, F. Parak, P. Schlecht and H. Eicher: Mössbauer studies on the electronic structure of ferrous iron in hemoglobin. Proc. of the 1st European Congress on Biophysics. Baden, Austria, Vol. VI, Y14 D9 (1971) (Abstract).

 

2.   A. Bundi, C. Grathwohl, J. Hochmann, R.M. Keller, G. Wagner and K. Wüthrich: Proton NMR of the Protected Tetrapeptides TFA-Gly-Gly-L-Ala-O-CH3, where X stands for one of the 20 common amino acids. J. Magn. Reson. 18, 191 (1975).

 

3. K. Wüthrich and G. Wagner: NMR investigations of the dynamics of the aromatic amino acid residues in the basic pancreatic trypsin inhibitor. FEBS Lett. 50, 265-268 (1975).

 

4. K. Wüthrich, J. Hochmann, R.M. Keller, G. Wagner, M. Brunori and G. Giacometti: 1H NMR relaxation in high spin ferrous hemoproteins. J. Magn. Reson. 19, 111 (1975).

 

5. G. Wagner and K. Wüthrich: Proton NMR studies of the aromatic residues in the basic pancreatic trypsin inhibitor (BPTI). J. Magn. Reson. 20, 435 (1975).

 

6. G. Wagner, A. DeMarco  and K. Wüthrich: Convolution difference spectra at 360 MHz of the basic pancreatic trypsin inhibitor. J. Magn. Reson. 20, 565 (1975).

 

7. K. Wüthrich and G. Wagner: High resolution NMR studies of the molecular dynamics of proteins in solution. Experientia 31, 726 (1975) (Abstract).

 

8. L.R. Brown, A. DeMarco, G. Wagner and K. Wüthrich: A study of the lysyl residues in the basic pancreatic trypsin inhibitor using 1H NMR at 360 MHz. Eur. J. Biochem. 62, 103 (1976).

 

9.   G. Wagner and K. Wüthrich: 1H NMR studies of the dynamics of the solution conformation of the basic pancreatic trypsin inhibitor (BPTI). Proc. XXIII Coll.-Protides of the Biological Fluids. London: Pergamon Press, 186 (1976).

 

10. K. Wüthrich, G. Wagner and H. Tschesche: Comparative 1H NMR studies of the cow colostrum trypsin inhibitor (CTI), the trypsin inhibitor of Helix pomatia (HPI) and the basic pancreatic trypsin inhibitor (BPTI). Proc. XXIII Coll.-Protides of the Biological Fluids. London: Pergamon Press, 201 (1976).

 

11. G. Wagner, A. DeMarco  and K. Wüthrich:  Dynamics of the aromatic amino acid residues in the globular conformation of the basic pancreatic trypsin inhibitor (BPTI). I. 1H NMR studies.  Biophys. Struct. Mechanism. 2, 139 (1976).

 

12. K. Wüthrich, G. Wagner and A. DeMarco:  NMR Studien der molekularen Dynamik von globulären Proteinen in Lösung: BPTI. Experientia 32, 802 (1977) (Abstract).

 

13. G. Wagner, R. Richarz and K. Wüthrich: pH dependent changes of breathing modes in a globular protein. Experientia 33, 802 (1977) (Abstract).

 

14. K. Wüthrich, G. Wagner, R. Richarz and A. DeMarco: Completion of X-ray structures of proteins by high resolution NMR. In "NMR in Biology" (R.A. Dwek, I.D. Campbell, R.E. Richards and R.J.P. Williams, eds.) Academic Press, London, 51 (1977).

 

15. A. DeMarco, H. Tschesche, G. Wagner  and K. Wüthrich:  1H NMR  studies at 360 MHz of the methyl groups in native and chemically modified basic pancreatic trypsin inhibitor (BPTI). Biophys. Struct. Mechanism 3, 303 (1977).

 

16. G. Wagner, K. Wüthrich and H. Tschesche: 1H NMR study of the conformation and the molecular dynamics of the glycoprotein cow colostrum trypsin inhibitor. Eur. J. Biochem. 86, 67-76 (1978).

 

17. G. Wagner, K. Wüthrich and H. Tschesche: A 1H NMR study of the solution conformation  of the isoinhibitor K from Helix pomatia. Eur. J. Biochem. 89, 367-377 (1978).

 

18. L.R. Brown, A. DeMarco, R. Richarz, G. Wagner and K. Wüthrich: The influence of a single salt bridge on the static and dynamic features of the globular solution conformation of the basic pancreatic trypsin inhibitor: 1H and 13C NMR studies of the native and transaminated inhibitor. Eur. J. Biochem. 88, 87-95 (1978).

 

19. K. Wüthrich, G. Wagner, R. Richarz and S.J. Perkins: Individual assignments of the methyl resonances in the 1H NMR spectrum of the basic pancreatic trypsin inhibitor (BPTI). Biochemistry 17, 2253-2263 (1978).

 

20. K. Wüthrich and G. Wagner: Dynamic aspects of protein conformation studied by nuclear magnetic resonance techniques - Evidence for hydrophobic stability domains in globular proteins. Proc. Intern. Symp. on Biomolecular Structure, Conformation, Function and Evolution, Madras, 1978, (R. Srinivasan, ed.) Pergamon Press, Oxford, Vol. 2, 23 (1980).

 

21. K. Wüthrich, G. Wagner and A. Bundi: NMR studies of molecular dynamics of peptides and proteins. In "Nuclear Magnetic Resonance Spectroscopy in Molecular Biology", Proceedings of the 11th Jerusalem Symposium on Quantum Chemistry and Biochemistry (B. Pullman, ed.) Reidel, Dodrecht, Holland, pp. 201-210 (1978).

 

22. G. Wagner and K. Wüthrich: Dynamic model of globular protein conformations based on NMR studies in solution. Nature 275, 247-248 (1978).

 

23. K. Wüthrich and G. Wagner: Internal motions in globular proteins. Trends in Biochemical  Sciences 3, 227-230 (1978).

 

24. K. Wüthrich, G. Wagner and R. Richarz: A dynamic model for globular protein conformations based on high resolution proton NMR data. In "Protein: Structure, Function and Industrial Applications". Proceedings of the 12th FEBS Meeting in Dresden (Hofmann et al., eds.), Pergamon Press, Oxford, England, 52, 143-152 (1979).

 

25. A. Dubs, G. Wagner and  K. Wüthrich: Individual assignments of amide proton resonances in the proton NMR spectrum of the basic pancreatic trypsin inhibitor. Biochim. Biophys. Acta 577, 177-194 (1979).

 

26. G. Wagner and K. Wüthrich: Truncated driven nuclear overhauser effect (TOE). A new technique for studies of selective 1H-1H Overhauser effects in the presence of spin diffusion. J. Magn. Reson. 33, 675-680 (1979).

 

27. G. Wagner, H. Tschesche and K. Wüthrich: The influence of a localized chemical modification of the basic pancreatic trypsin inhibitor on static and dynamic aspects of the molecular conformation in solution. Eur. J. Biochem. 95, 239-248 (1979).

 

28. G. Wagner, A.J. Kalb and K. Wüthrich: Conformational studies by 1H NMR of the basic pancreatic trypsin inhibitor after reduction of the disulfide bond 14-38. Influence of charged protecting groups on the stability of the protein. Eur. J. Biochem. 95, 249-253  (1979).

 

29. H. Roder, R. Richarz, G. Wagner and K. Wüthrich: NMR studies of the reversible thermal denaturation of the basic pancreatic trypsin inhibitor. Experientia 35, 942 (1979) (Abstract).

 

30. K. Wüthrich and G. Wagner: Nuclear magnetic resonance of labile protons in the basic pancreatic trypsin inhibitor. J. Mol. Biol. 130, 1-18 (1979).

 

31. R. Richarz, P. Sehr, G. Wagner and K. Wüthrich: Kinetics of the exchange of individual amide protons in the basic pancreatic trypsin inhibitor. J. Mol. Biol. 130, 19-30 (1979).

 

32. G. Wagner and K. Wüthrich: Correlation between the amide proton exchange rates and the denaturation temperature in globular proteins related to the basic pancreatic trypsin inhibitor. J. Mol. Biol. 130, 31-37 (1979).

 

33. G. Wagner and K. Wüthrich: Structural interpretation of the amide proton exchange in the basic pancreatic trypsin inhibitor and related proteins. J. Mol. Biol. 134, 75-94 (1979).

 

34. K. Wüthrich, H. Roder and G. Wagner: Internal Mobility and Unfolding of Globular Proteins. In "Protein Folding" (R. Jaenicke, ed.), Elsevier/North Holland Biomedical Press. 549-564 (1980).

 

35. K. Wüthrich, G. Wagner, R. Richarz and W. Braun: Correlation between Internal Mobility and Stability of Globular Proteins. Biophysical J. 32, 549-560 (1980).

 

36. G. Wagner: Activation Volumes DV ‡ for the Rotational Flips of Internal Aromatic Rings in Globular Proteins, Determined by High Resolution 360 MHz  1H NMR at Variable Pressure. Experientia 36, 735 (1980) (Abstract).

 

37. G. Wagner: Activation Volumes for the Rotational Motion of Interior Aromatic Rings in Globular Proteins Determined by High Resolution  1H NMR at Variable Pressure. FEBS Letters 112, 280-284 (1980).

 

38.   G. Wagner: A Novel Application of Nuclear Overhauser Enhancement (NOE) in Proteins: Analysis of Correlated Events in the Exchange of Internal Labile Protons. Biochem. Biophys. Res. Comm. 97, 614-620 (1980).

 

39.   K. Wüthrich, A. Eugster and G. Wagner: p2H Dependence of the Exchange with the Solvent of Interior Amide Protons in Basic Pancreatic Trypsin Inhibitor Modified by Reduction of the Disulfide Bond 14-38. J. Mol. Biol. 144, 601-604 (1980).

 

40.   A. Kumar, G. Wagner, R.R. Ernst and K. Wüthrich: Studies of J-Connectivities and Selective 1H -1H  Overhauser Effects in H2O Solutions of Biological Macromolecules by Two-Dimensional NMR Experiments. Biochem. Biophys. Res. Comm. 96, 1156-1163  (1980).

 

41.   G. Wagner: Examples of Exchange Phenomena in the Basic Pancreatic Trypsin Inhibitor. In "Protein Dynamics and Energy Transduction", Proc. of the VIth Taniguchi International Symposium, Biophysics Division, Sanda, Japan (ed. S. Ishiwata), 56-82 (1980).

 

42. G. Wagner, A. Kumar and K. Wüthrich: Systematic Application of Two-Dimensional 1H  NMR Techniques for Studies of Proteins 2. Combined use of Correlated Spectroscopy and Nuclear Overhauser Spectroscopy for Sequential Assignments of Backbone Resonances and Elucidation of Secondary Structures. Eur. J. Biochem. 114, 375-384 (1981).

 

43.   A. Kumar, G. Wagner, R.R. Ernst and K. Wüthrich: Build-up Rates of the Nuclear Overhauser Effects Measured by Two-Dimensional Proton Magnetic Resonance Spectroscopy: Implications for Studies of Protein Conformation. J. Am. Chem. Soc. 103, 3654-3658 (1981).

 

44.   G. Wagner: Internal Mobility in Globular Proteins. Comments Mol. Cell. Biophys. 1, 261-280 (1982).

 

45. K. Wüthrich, G. Wider, G. Wagner and W. Braun: Sequential Resonance Assignments as a Basis for Determination of Spatial Protein Structures by High Resolution Proton Nuclear Magnetic Resonance. J. Mol. Biol. 155, 311-319 (1982).

 

46.   G. Wagner and K. Wüthrich: Sequential Resonance Assignments in Protein 1H NMR Spectra: Basic Pancreatic Trypsin Inhibitor J. Mol. Biol. 155, 347-366 (1982).

 

47.   K. Wüthrich and G. Wagner: NMR Studies of Concerted Motions in the Interior and on the Surface of Globular Proteins. Proc. Ciba Foundation Symposium on Internal Motions in Proteins, London, 1982, pp. 310-328 (1982).

 

48.   G. Wagner and K. Wüthrich: Amide Proton Exchange and Surface Conformation of the Basic Pancreatic Trypsin Inhibitor (BPTI) in Solution: Studies with Two-Dimensional Nuclear Magnetic Resonance. J. Mol. Biol. 160, 343-361 (1982).

 

49. G. Wagner and K.  Wüthrich:  Dynamik von Proteinstrukturen. Naturwissenschaften 70, 105-114 (1983).

 

50. G. Wagner: Characterization of the distribution of internal motions  in  the basic pancreatic trypsin inhibitor using  a large number of internal NMR  probes.  Quart.  Rev.  Biophys. 16, 1-57 (1983).

 

51.   G.  Wagner, A. Pardi and K. Wüthrich: Hydrogen bond length and  1H NMR chemical shifts in proteins. J. Am. Chem. Soc. 105, 5948-5949 (1983).

 

52.   G.  Wagner  and E.R.P.  Zuiderweg:  Two-dimensional  double quantum 1H NMR spectroscopy of proteins. Biochem. Biophys. Res. Comm. 113, 854-860 (1983).

 

53. G.  Wagner:  Two-dimensional  relayed  coherence  transfer spectroscopy of a protein.  J.  Magn.  Reson. 55, 151-156 (1983).

 

54.   A.  Pardi, G. Wagner and K. Wüthrich: Protein conformation and proton nuclear magnetic resonance chemical shifts.  Eur. J. Biochem. 137, 445-454 (1983).

 

55. M.  Rance,  O.W.  Sørensen, G. Bodenhausen, G. Wagner, R.R Ernst and K. Wüthrich: Improved spectral resolution in COSY 1H  NMR spectra of proteins via double quantum  filtering. Biochem. Biophys. Res. Comm. 117, 479-485 (1983).

 

56.   M.  Rance,  G.  Wagner, O.W. Sørensen, K. Wüthrich and R.R. Ernst: Application of w1-decoupled 2D correlation spectra to the study of proteins.  J.  Magn.  Reson.  59, 250-261 (1984).

 

57. G.  Wagner:  2D relayed coherence transfer-NOE spectroscopy (relayed NOESY). J. Magn. Reson. 57, 497-505 (1984).

 

58.   D. Neuhaus, G. Wider, G. Wagner and K. Wüthrich: X-relayed 1H -1H correlated spectroscopy.  J.  Magn.  Reson. 57, 164-168 (1984).

 

59. G. Wagner and K. Wüthrich: Observation of internal motility  of  proteins  by  nuclear magnetic  resonance  in  solution.  Methods in Enzymology,  131, 307-326 (1986)

 

60.   K.  Wüthrich and G. Wagner: Internal dynamics in proteins.Trends Biochem. Sci. 9, 152-154 (1984).

 

61. D.  Neuhaus,  G.  Wagner,  M.  Vasak,  J.H.R.  Kägi and K. Wüthrich:  113Cd-1H  spin-spin couplings in homonuclear 1H    correlated    spectroscopy of    metallothionein. Identification  of  cysteine  1H  spin  systems.  Eur.  J. Biochem. 14, 659-667 (1984).

 

62. C.I.  Stassinopoulou,  G.  Wagner and  K.  Wüthrich:  Two- dimensional  1H  NMR of two chemically modified analogs  of  the  basic pancreatic trypsin inhibitor.  Sequence  specific resonance assignments and sequence  location  of conformation changes relative to the native protein. Eur. J. Biochem. 145, 423-430 (1984).

 

63. G.  Wagner,  C.I.  Stassinopoulou and K.  Wüthrich:  Amide proton  exchange studies by two-dimensional correlated  1H  NMR   in  two  chemically  modified  analogs  of  the  basic pancreatic trypsin inhibitor.  Eur. J. Biochem. 145, 431- 436 (1984).

 

64. G.  Bodenhausen,  G.  Wagner,  M.  Rance, O.W. Sørensen, K. Wüthrich and R.R.  Ernst: Longitudinal two-spin order in 2D exchange spectroscopy (NOESY) J. Magn. Reson. 59, 542-550 (1984).

 

65. M.  Rance, G. Bodenhausen, G. Wagner, K. Wüthrich and R.R. Ernst:  A systematic approach to the suppression of J cross- peaks in 2D exchange spectroscopy. J. Magn. Reson. 62, 497-510 (1985).

 

66. H.  Roder,  G.  Wagner and K.  Wüthrich:  Individual amide  proton exchange rates in thermally unfolded basic pancreatic trypsin inhibitor. Biochemistry, 24, 7407-7411 (1985).

 

67. H. Roder, G. Wagner and K. Wüthrich: Amide proton exchange in  proteins  by  EX1 kinetics:   Studies  of  the  basic  pancreatic   trypsin   inhibitor   at  various   p2H   and temperature. Biochemistry, 24, 7396-7407 (1985).

 

68. W. Denk, G. Wagner, M. Rance and K. Wüthrich: Combined suppression of diagonal  peaks and t1-ridges in  two-dimensional  nuclear  Overhauser enhancement spectra.  J. Magn. Reson. 62, 350- 355 (1985).

 

69. G.  Wagner,  G.  Bodenhausen,  N.  Müller,  M. Rance, O.W. Sørensen,  R.R. Ernst and K. Wüthrich: Exchange of two-spin order in nuclear magnetic resonance:  separation of exchange and  cross  relaxation  processes.   J.   Am.   Chem.  Soc., 107, 6440-6446 (1985).

 

70. D.  Neuhaus,  G.  Wagner,  M.  Vasak,  J.H.R.  Kägi and K. Wüthrich:  Systematic application of high resolution, phase sensitive   two-dimensional  1H  NMR  techniques  for  the identification  of  the amino acid proton  spin  systems  in proteins:  rabbit liver metallothionein-2. Eur. J. Biochem., 151, 257-273 (1985).

 

71. M.H.  Frey, G. Wagner, M. Vasak, O.W. Sørensen, D. Neuhaus, E. Wörgötter, J.H.R.  Kägi  and K.  Wüthrich: Polypeptide-metal cluster connectivities  in metallothionein-2 by  novel  1H -113Cd heteronuclear two-dimensional NMR experiments.  J. Am. Chem. Soc., 107, 6847-6851 (1985).

 

72. W. Braun, G. Wagner, E. Wörgötter, M. Vasak, J.H.R. Kägi  and K. Wüthrich: Polypeptide fold in the two meytal cluster of metallothionein-2 by nuclear magnetic resonance in solution J. Mol. Biol., 187, 125-129 (1986).

 

73. G. Wagner, D. Neuhaus, E. Wörgötter, M. Vasak, J.H.R. Kägi and K. Wüthrich: Nuclear Magnetic Resonance identification of "half-turn" and 310-helix secondary structures in rabbit liver metallothionein-2. J. Mol. Biol., 187, 131-135 (1986).

 

74. G. Wagner, D. Neuhaus, M. Vasak, E. Wörgötter, J.H.R. Kägi  and K. Wüthrich: Sequence specific 1H  NMR assignments in rabbit liver metallothionein-2. Eur. J. Biochem., 157, 275-289 (1986).

 

75. G. Otting, H. Widmer, G. Wagner and K. Wüthrich: t1- and  t2-ridges in 2D-NMR Spectra: Origin and Procedures for Suppression. J. Magn. Reson., 66, 187-193 (1986).

 

76. W. Denk, R. Baumann and G. Wagner: Quantitative evaluation of cross peak intensities by projection of two-dimensional NOE  spectra on a linear space spanned by a set of reference resonance lines. J. Magn. Reson., 67, 386-390 (1986).

 

77. G. Wagner, M.H. Frey, D. Neuhaus, E. Wörgötter, W. Braun, M. Vasak, J.H.R. Kägi and K. Wüthrich: Spatial Structure of Rabbit Liver Metallothionein-2 in Solution by NMR. Proc. 2nd International Meeting on Metallothionein, Zürich, Aug. 1985, Birkhäuser Verlag, Basel, pp. 149-157.

 

78. D. Brühwiler and G. Wagner: Selective Excitation of 1H resonances coupled to 13C : Heteronuclear COSY and RELAY experiments with 1H Detection. J. Magn. Reson., 69, 546-551 (1986).

 

79. E. Wörgötter, G. Wagner and K. Wüthrich: Simplification of two-dimensional 1H NMR spectra using a X-filter. J. Am. Chem. Soc., 108, 6162-6167 (1986).

 

80. G. Wagner and D. Brühwiler: Toward the complete assignment of the carbon Nuclear Magnetic Resonance spectrum of the basic pancreatic trypsin inhibitor. Biochemistry, 25, 5839-5843 (1986).

 

81. G. Wagner,  W. Braun, T. Havel, T. Schaumann,  N. Go and K. Wüthrich: Protein Structures in Solution by Nuclear Magnetic Resonance and Distance Geometry. The Polypeptide Fold of the Basic Pancreatic Trypsin Inhibitor Determined using Two Different Algorithms, DISGEO and DISMAN.J. Mol. Biol.,196, 611-639 (1987).

 

82. G. Otting, H. Senn, G. Wagner and K. Wüthrich: Editing of 2D 1H NMR spectra Using X Half-Filters: Combined Use with Residue Selective 15N-Labeling of Proteins. J. Magn. Reson., 70, 500-505 (1986).

 

83. G. Wagner and K. Wüthrich: Reply to the Comments on "Amide Proton Exchange Studies by two-dimensional correlated 1H NMR in two chemically  modified analogs of the basic pancreatic trypsin inhibitor". Eur. J. Biochem.  157, 617-618 (1987).

 

84. S.G. Hyberts, W. Märki and G. Wagner: Stereospecific assignments of side chain protons and characterization of torsion angles. Eur. J. Biochem. , 164, 625-635 (1987).

 

85. W. Leupin, G. Wagner, W.A. Denny and K. Wüthrich:  Assignment of the  13C nuclear magnetic resonance spectrum of a short DNA douplex with 1H detected two-dimensional heteronuclear correlation spectroscopy. Nucleic Acid Res. , 15, 267-275 (1987).

 

86. G. Wagner, D. Brühwiler and K. Wüthrich: Reinvestigation of the aromatic side chains in the basic pancreatic trypsin inhibitor by heteronuclear two-dimensional nuclear magnetic resonance. J. Mol. Biol.  196, 227-231 (1987).

 

87. M. Vasak, E. Wörgötter, G. Wagner, J.R.H. Kägi and K. Wüthrich: Metal coordination in rat liver metallothionein-2 prepared with or without reconstitution of the metal clusters and comparison with rabbit liver metallothionein. J. Mol. Biol., 196, 711-719 (1987).

 

88. E. Wörgötter, G. Wagner, M. Vasak, J.H.R. Kägi and K. Wüthrich: Sequence specific 1H  NMR assignments in rat liver metallothionein-2. Eur. J. Biochem. 167, 457-466 (1987).

 

89. H. Widmer, G. Wagner, H. Schweitz, M. Lazdunski and K. Wüthrich: The secondary structure of the toxin ATX Ia from anemonia sulcata in aqueous solution determined on the basis of complete sequence specific  1H NMR assignments. Eur. J. Biochem. , 171, 177-192 (1988).

 

90. E. Wörgötter, G. Wagner, M. Vasak, J.H.R. Kägi and K. Wüthrich: Heteronuclear filters for two-dimensional 1H NMR identification of the metal-bound amino acids in metallothionein and observation of small heteronuclear long-range couplings. J. Am. Chem. Soc., 110, 2388-2393 (1988).

 

91 A. Arseniev, P. Schultze, E. Wörgötter, W. Braun, G. Wagner,  M. Vasak, J.H.R. Kägi and K. Wüthrich: The three-dimensional structure of rabbit liver [Cd7]-metallothionein-2 in aqueous solution determined by nuclear magnetic resonance. J. Mol. Biol., 201, 637-657 (1988).

 

92. P. Schultze, E. Wörgötter, W. Braun, G. Wagner, M. Vasak, J.H.R. Kägi and  K. Wüthrich: The conformation of [Cd7]-metallothionein-2 from rat liver in aqueous solution determined by nuclear magnetic resonance.  J. Mol. Biol., 203, 251-268 (1988).

 

93. G. Wagner: Heteronuclear NMR experiments for studies of protein conformation. Methods in Enzymology, 176, 93-113 (1989).

 

94. G. T. Montelione, M.E. Winkler, L.E. Bourton, E. Rinderknecht, M.B. Sporn and G. Wagner: Identification of two antiparallel b-sheet conformations in the solution structure of human recombinant type-a transforming growth factor by proton magnetic resonance, Proc. Natl. Acad. Sci., 86, 1519- 1523 (1989).

 

95. N.R. Nirmala and G. Wagner: Measurements of 13C relaxation times in proteins by two-dimensional heteronuclear 1H-13C correlation spectroscopy, J. Am. Chem. Soc., 110, 7557-7558 (1988).

 

96. S.G. Hyberts and G. Wagner: Taylor  transformation of 2D NMR tm series from time dimension to polynomial dimension, J. Magn. Reson. , 81, 418-422 (1989).

 

97. G. T. Montelione and G. Wagner: 2D chemical exchange NMR spectroscopy by proton detected heteronuclear correlation, J. Am. Chem. Soc., 111, 3096-3098 (1989).

 

98. G. T. Montelione, M.E. Winkler, P. Rauenbuehler and G. Wagner:  Accurate measurements of long-range heteronuclear coupling constants from homonuclear 2D NMR spectra of isotope-enriched proteins, J. Magn. Reson., 82, 198-204 (1989).

 

99. N.R. Nirmala and G. Wagner: Measurement of 13C spin-spin relaxation times by two-dimensional heteronuclear 1H-13C correlation spectroscopy, J. Magn. Reson., 82, 659-661 (1989).

 

100. G. Wagner and N.R. Nirmala: Measurements of Individual 13C Relaxation Times and Hydrogen Exchange Rates in Proteins by 2D NMR: Inferences for Interpretation of Structural Data. Chemica Scripta 29A, 27-30 (1989).

 

101. G.T. Montelione and G. Wagner: Accurate Measurements of Homonuclear HN-Ha Coupling Constants in Polypeptides Using Heteronuclear 2D NMR Experiments. J. Am. Chem. Soc., 111, 5474-5475 (1989).

 

102. G. Wagner, N.R. Nirmala, G.T. Montelione and S.G. Hyberts: Static and Dynamic Aspects of Protein Structure, Frontiers of NMR in Molecular Biology, UCLA  Symposia on Molecular and Cellular Biology, New Series, Vol. 109, Editors, D. Live, I. Armitage and D. Patel, Alan R. Liss, Inc., New York, NY (1989), pp. 129-143.

 

103.  G. Wagner, S.G. Hyberts, D.W. Heinz and M.G. Grütter:  NMR Characterization of Point Mutations on the Elastase Inhibitor Eglin c - Correlations with Functional Properties, in Structure & Methods, Vol. 2: DNA Complexes & Proteins, (Sarma & Sarma eds.), pp. 93-101,  Adenine Press, Albany, New York, (1990).

 

104. S.G. Hyberts and G. Wagner: Sequence-specific 1H NMR Assignments and Secondary Structure of Eglin c. Biochemistry, 29, 1465-1474 (1990).

 

105. G.T. Montelione and G. Wagner: Conformation-Independent Sequential NMR Connections in Isotope-Enriched Polypeptides by H-1-C-13-N-15 Triple-Resonance Experiments. J. Magn. Reson., 87, 183-188 (1990).

 

106. G.T. Montelione and G. Wagner: 1H-13C-15N Triple Resonance Experiments For Accurate Measurements of Homonuclear Coupling Constants in Proteins. Relaxation Times, 6, 2-3 (1989).

 

107. G. Wagner: NMR Investigations of Protein Structure, Progress NMR Spectroscopy, 22, 101-139 (1990).

 

108. D.J. Detlefsen, V. Thanabal, V.L. Pecoraro and G. Wagner: Sequential 1H NMR assignments of Fe(II) cytochrome c551 from Pseudomonas aeruginosa. Biochemistry, 29, 9377-9386 (1990).

 

109. M. Adler and G. Wagner: Removal of Dispersive Baseline Distortions Caused by Strong Water Signals. J. Magn. Reson., 91, 450-454 (1991).

 

110. J.W. Peng, V. Thanabal and G. Wagner: 2D Heteronuclear NMR Measurements of spin-lattice Relaxation times in the rotating frame of X nuclei in heteronuclear HX spin systems, J. Magn. Reson., 94, 82-100 (1991).

 

111. G. Wagner, P. Schmieder and V. Thanabal: A new 1H-15N-13C triple resonance experiment for sequential assignments and measuring homonuclear Ha-HN vicinal coupling constants in polypeptides, J. Magn. Reson., 93, 436-440 (1991).  

 

112. M. Adler, R. Lazarus, M. Dennis and G. Wagner: Solution structure of kistrin a potent platelet aggregation inhibitor and integrin GPIIbIIIa antagonist, Science, 253, 445-448 (1991).

 

113. R. T. Clubb, V. Thanabal, C. Osborne and G. Wagner: 1H and 15N Resonance Assignments of Oxidized Flavodoxin from Anacystis nidulans with 3D NMR, Biochemistry, 30, 7718-7730 (1991).

 

114. B.J. Stockman, N.R. Nirmala, G. Wagner, T.D. Delcamp, M.T. DeYarman and J.H. Freisheim: Methotrexate binds in a non-productive orientation to human dihydrofolate reductase in solution based on NMR spectroscopy, FEBS Letters, 283, 267-269 (1991).

 

115. P. Schmieder, V. Thanabal, L. P. Mcintosh, F.W. Dahlquist and G. Wagner: Measurements of Ha-HN vicinal coupling constants in a protein with large line widths using a new 3D 1H-15N-13C quadruple resonance NMR experiment,  J. Am. Chem. Soc., 113, 6323-6324 (1991).

 

116. J.W. Peng, V. Thanabal and G. Wagner: Improved Accuracy of Heteronuclear Transverse Relaxation Time Measurements in Macromolecules: Elimination of Antiphase Contributions, J. Magn. Reson., 95, 421-427 (1991).

 

117. D.J. Detlefsen, V. Thanabal, V.L. Pecoraro and G. Wagner: Solution structure of Fe(II) cytochrome c551 from Pseudomonas aeruginosa as determined by 2D 1H-NMR, Biochemistry, 30, 9040-9046 (1991).

 

118. J.W. Peng and G. Wagner: Mapping of Spectral Density Functions Using Heteronuclear NMR Relaxation Measurements, J. Magn. Reson., 98, 308-332 (1992).

 

119. G.T. Montelione, K. Wüthrich, A.W. Burgess, E.C. Nice, G. Wagner, K.D. Gibson and H.A. Scheraga: Solution structure of murine epidermal growth factor determined by NMR spectroscopy and refined by energy minimization with restraints, Biochemistry, 31, 236-249 (1992).

 

120. G. Wagner, V. Thanabal, B. J. Stockman, J. W. Peng,  N. R. Nirmala, Sven G. Hyberts, Matthew S. Goldberg, David Detlefsen, Robert T. Clubb and Marc Adler: NMR Studies of Structure and Dynamics of Isotope Enriched Proteins, Biopolymers, 32, 381-390 (1992).

 

121. B. J. Stockman, N. R. Nirmala, G. Wagner, Tavner J. Delcamp, Michael T. DeYarman and James, H. Freisheim: Sequence Specific 1H and 15N Resonance Assignments for Human Dihydrofolate Reductase in Solution, Biochemistry, 31, 218-229 (1992).

 

122. M. Adler and G. Wagner: Sequential 1H NMR Assignments of Kistrin, a Potent Platelet Aggregation Inhibitor and Glycoprotein IIb-IIIa Antagonist, Biochemistry, 31, 1031-1039 (1992).

 

123. G. Wagner:  NMR as a tool for protein molecular design, Chemical Design Automation News, 6, 12-18 (1991). 

 

124. G. Wagner, S. G. Hyberts and T.F. Havel: NMR structure determination in solution: a critique and comparison with X-ray crystallography, Ann Rev. Biophys. Biomol. Struct. 21, 167- 198 (1992). 

 

125. R. T. Clubb, V. Thanabal, and G. Wagner: A New 3D HN(CA)HA experiment for obtaining fingerprint HN-Ha cross peaks in 15N and 13C labeled proteins, J. Biomol. NMR, 2, 203-210 (1992).

 

126.  R. T. Clubb, V. Thanabal, and G. Wagner: A Constant time three-dimensional triple resonance pulse scheme to correlate intraresidue HN, 15N and 13C' chemical shifts in 15N-13C labeled proteins, J. Magn. Reson., 97, 213-217 (1992).

 

127. S.G. Hyberts, M.S. Goldberg, T.F. Havel and G. Wagner: The solution structure of eglin c based on measurements of many NOEs and coupling constants and its comparison with X-ray structures. Protein Science, 1, 736-751 (1992).

 

128. J. D. Baleja, R. Marmorstein, S.C. Harrison and G. Wagner: Solution structure of the DNA-binding domain of Cd2-GAL4 from Saccaromyces cervisiae, Nature, 356, 450-453 (1992).

 

129. D.W. Heinz, S.G. Hyberts, J.W. Peng, J.P. Priestle, G. Wagner and M. Grütter: Changing the inhibitory specificity and function of the proteinase inhibitor eglin c by site-directed mutagenesis: Functional and structural Investigation, Biochemistry, 31, 8755-8766 (1992).

 

130. W. Braun, M. Vasak, A.H. Robbins, C.D. Stout, G. Wagner, J.H.R. Kägi and K. Wüthrich: Comparison of the X-ray Crystal Structure and the NMR solution structure of Rat metallothionein-2, Proc. Natl. Acad. Sci., USA, 89, 10124-10128 (1992).

 

131. M.D. Reily, V. Thanabal, E.A. Lunney, J.T. Repline, C.C. Humblet and G. Wagner: Design, Synthesis and solution structure of a renin inhibitor. Structural constraints from NOE and homonuclear and heteronuclear coupling constants combined with distance geometry calculations. FEBS Letters, 302, 97-103 (1992).

 

132.  R. T. Clubb and G. Wagner: A triple resonance pulse scheme for selectively correlating amide 1HN and 15N nuclei with the Ha proton of the preceding residue, J. Biomol. NMR, 2, 389-394 (1992).

 

133.  J. W. Peng and G. Wagner: Mapping of Spectral Densities of N-H Bond Motions in Eglin c Using Heteronuclear Relaxation Experiments.  Biochemistry, 31, 8571-8586 (1992).

 

134.  G. Wagner, S.G. Hyberts & J.W. Peng: Study of Protein Dynamics by NMR, in "NMR of Proteins" (Clore, G.M. & Gronenborn , A.M., eds.), Topics in Molecular and Structural Biology, MacMillan Press, 220-257 (1993).

 

135. T. Mau, J. Baleja & G. Wagner: Effects of DNA Binding and Metal Substitution on the Dynamics of the Gal4 DNA Bindig Domain as Studied by Amide Proton Exchange. Protein Science, 1, 1403-1412 (1992).

 

136. J.D. Baleja, V. Thanabal, T. Mau and G. Wagner: Solution structure of the DNA-binding domain of GAL4 from Saccharomyces cervisiae. Bull. Magn. Reson., 14, 175-180 (1992).

 

137. M. Adler, P. Carter, R.A. Lazarus and G. Wagner: Cystein pairing in the glycoprotein IIbIIIa antagonist kistrin using NMR, chemical analysis and structure calculations. Biochemistry, 32, 282-289 (1993).

 

138. K. Moffat and G. Wagner: Biophysical methods, editorial overview. Current Opinion in Structural Biology, 2, 803-804 (1992).

 

139. R. T. Clubb, V. Thanabal, J. Fejzo, S.B. Ferguson, L. Zydowsky, C.H. Baker, C.T. Walsh and G. Wagner: Secondary structure and backbone resonance assignments of the periplasmic cyclophilin type peptidyl-prolyl isomerase from Escherichia coli. Biochemistry, 32, 6391-6401 (1993). 

 

140. J.W. Peng and G. Wagner: Investigation of protein motions via relaxation measurements. Methods in Enzymology, 239, 563-596 (1994).

 

141. G. Wagner: Prospects of NMR for large proteins, J. Biol. NMR, 3, 375-385 (1993).

 

142. P. Schmieder, A.S. Stern, G. Wagner and J.C. Hoch: Application of non-linear sampling schemes to COSY-type spectra. J. Biomol. NMR, 3, 569-576 (1993).

 

143. J.W. Peng and G. Wagner: Protein Mobility from Multiple 15N Relaxation Parameters. In "NMR Probes of Molecular Dynamics",  373-454, R. Tycko, ed., Kluwer Academic Publishers (1994).

 

144. L.E. Myers, A.E. Ferentz, M.P. Terranova, G. Wagner and G.L. Verdine: Repair of DNA methylphosphotriesters through a metalloactivated cysteine nucleophile. Science, 261, 1164-1167 (1993).

 

145.  L.E. Myers,  G.L. Verdine and G. Wagner:  Solution structure of the DNA methylphosphotriester repair domain of E.Coli ada. Biochemistry, 32, 14089-14094 (1993).

 

146. D. F. Wyss, J. M. Withka, M. H. Knoppers, K. A. Sterne, M. A. Recny and G. Wagner: 1H Resonance Assignments and Secondary Structure of the 13.6 kDa Glycosylated Adhesion Domain of Human CD2. Biochemistry, 32, 10995-11006 (1993).

 

147. J. Lee, J. Fejzo and G. Wagner: An inverted HSQC w2 -half filtered NOESY with pulsed field gradients. J. Magn. Reson.Ser. B, 102, 322-325 (1993). 

 

148. G. Wagner: NMR relaxation and protein mobility. Current Opinion in Structural Biology, 3, 748-754 (1993).

 

149. J.M. Withka, D.F. Wyss, G. Wagner, A.R.N. Arulanandam, E.L. Reinherz and M.A. Recny: Structure of the glycosylated adhesion domain of human T lymphocyte glycoprotein CD2. Structure, 1, 69-81 (1993).

 

150. M.A. Markus, T. Nakayama, P. Matsudaira and G. Wagner: Solution structure of villin 14T, a domain conserved among actin-severing proteins. Protein Science, 3, 70-81 (1994).

 

151. A.R.N. Arulanandam, J.M. Withka, D.F. Wyss, G. Wagner, A. Kister, M.A. Recny and E.L. Reinherz: The CD58 (LFA-3) binding site is a localized and highly charged surface area on the ACFCC'C" face of human CD2 domain 1. Proc. Nat. Acad. Sci. USA, 90, 11613-11617 (1993).

 

152. R. T. Clubb, S. B. Ferguson, C. T. Walsh and G. Wagner: Three-Dimensional Solution Structure of Escherichia coli Periplasmic Cyclophilin. Biochemistry, 33, 2761-2772 (1994).

 

153. P. Schmieder, A.S. Stern, G. Wagner and J.C. Hoch: Improved resolution in triple resonance spectra by non-linear sampling in the constant time domain.. J. Biomol. NMR, 4, 483-490 (1994).

 

154. J. Fejzo,  F.A. Etzkorn, R.T. Clubb, Y. Shi, C.T. Walsh and G. Wagner: The mutant E.coli F112W cyclophilin binds cyclosporin A in nearly identical conformation as human cyclophilin. Biochemistry, 33, 5711-5720 (1994).

 

155. J. D. Baleja, T. Mau and G. Wagner: Recognition of DNA by GAL4 in solution: Use of a monomeric protein-DNA complex for study by NMR. Biochemistry, 33, 3071-3078 (1994).

 

156. M.A. Markus,  T. Nakayama, P. Matsudaira and G. Wagner:  1H, 15N, 13C and 13CO resonance asignments and secondary structure of villin 14T, a domain conserved among actin-severing proteins, J. Biomol. NMR, 4, 553-574 (1994).

 

157. A. M. Krezel, G. Wagner, J. Seymour-Ulmer and R. Lazarus and  Structure of the RGD protein decorsin: conserved motif and distinct function in leech proteins that affect blood clotting, Science, 264, 1944-1947 (1994).

 

158. G. Wagner: Principles of Multidimensional NMR, in “NMR of Biological Macromolecules”  (C. K. Stassinopoulou ed.), Proceedings of the NATO Advanced Study Institute,  held at Kolympari, Crete, Springer-Verlag, Berlin pp. 17-36 (1994).

 

159. G. Wagner: NMR of Proteins. Encyclopedia of Magnetic Resonance, 1, 680-682 (1995).

 

160. A.R.N. Arulanandam, A. Kister, M.J. McGregor, D.F. Wyss, G. Wagner, and E.L. Reinherz: Interaction between CD2 and CD58 involves the major b sheet surface of each of their respective adhesion domains. J. Exp. Med.,180, 1861-1871 (1994).

 

161. J.-X. Yang, A. Krezel, P. Schmieder, G. Wagner & T. F. Havel: An evaluation of least-squares fits to COSY spectra as a means of estimating proton-proton coupling constants. Part II Applications to polypeptides. J. Biomol. NMR, 4, 827-844 (1994).

 

162. M. A. Markus, K.T. Dayie, P. Matsudaira and G. Wagner: Effect of deuteration on the amide proton relaxation rates in proteins: Heteronuclear NMR experiments on villin 14T. J. Magn. Reson.B, 105, 192-195 (1994).

 

163. K.T. Dayie & G. Wagner: Relaxation-rate measurements for 15N-1H groups with pulsed-field gradients and preservation of coherence pathways. J. Magn. Reson., A 111, 121-126 (1994).

 

164. L.C. Myers, T.D. Cushing, G. Wagner and G.L. Verdine: Metal-coordination sphere in the methylated ada protein/DNA co-complex. Chemistry & Biology, 1, 91-97 (1994).

 

165. G. Wagner: Thin end of the wedge. Nature Str. Biol. 1, 497-498 (1994).

 

166. E. Meiering & G. Wagner: Detection of tightly bound structural and functional water molecules in complexes of human dihydrofolate reductase with methotrexate and NADPH by NMR. J. Mol. Biol., 247, 294-308 (1995).

 

167. E. M. Meiering, H. Li, T.J. Delcamp, J.H. Freisheim and G. Wagner, Contributions of tryptophan 24 and glutamate 30 to binding long-lived water molecules in the ternary complex of human dihydrofolate reductase with methotrexate and NADPH studied by site-directed mutagenesis and nuclear magnetic resonance spectroscopy.  J. Mol. Biol., 247, 309-325 (1995).

 

168. G. Wagner and D. Wyss: Cell surface adhesion receptors. Curr. Op. Str. Biol.,4, 841-851 (1994).

 

169. D.F. Wyss, J. S. Choi and G. Wagner: Composition and sequence specific resonance assignments of the heterogeneous N-linked glycan in the 13.6 kDa adhesion domain of human CD2 as determined by NMR on the intact glycoprotein. Biochemistry, 34, 1622-1634 (1995).

 

170. A.R.N. Arulanandam, J.M. Withka, D.F. Wyss, G. Wagner, A. Kister, P. Pallai, M.A. Recny and E.L. Reinherz: The CD58 (LFA-3) binding site is a localized and highly charged surface area on the ACFCC'C" face of human CD2 domain. In “Leucocyte typing V” Oxford University Press, Oxford, in press (1995).

 

171. G. Wagner: Cadherin: A distant member of the immunoglobulin superfamily. Science, 267, 342 (1995).

 

172. A. Krezel, C. Khasibhatla, P. Hidalgo, R. McKinnon and G. Wagner: Solution structure of the potassium channel inhibitor agitoxin 2: calipers for probing channel geometry. Protein Science, 4, 1478-1489 (1995).

 

173. G. Wagner: The importance of being floppy. Nature Struct. Biol. 2, 255-257 (1995).

 

174. J. Habazettl and G. Wagner: A new simplified method for analyzing nitrogen-15 nuclear magnetic relaxation data of proteins. J. Magn. Reson., B 109, 100-104 (1995).

 

175. J. Habazettl, L.  C. Myers, F. Yuan, G. L. Verdine and G. Wagner: Analysis of Backbone Dynamics, Amide Hydrogen Exchange, and Resonance Assignments of the DNA Methylphosphotriester Repair Domain of Escherichia coli Ada Using NMR. Biochemistry,  35, 9335-9348 (1996).

 

176. P. Zhang, S. Talluri. H. Deng, D. Branton, G. Wagner: Solution structure of the pleckstring homology domain of Drosophila b-spectrin. Structure, 3, 1185-1195 (1995). 

 

177. D.F. Wyss J. S. Choi, J. Li, M. H. Knoppers, K. J. Willis, A. R. N. Arulanandam, A. Smolyar, E. L. Reinherz, G. Wagner:. CHO structure, Conformation and Function of the N-linked Glycan in the Adhesion Domain of Human CD2. Science, 269, 1273-1278 (1995).

 

178. J. Chen, R. Peters, P. Saha, P. Lee, A. Theodoras, M. Pagano, G. Wagner and A. Dutta: A 39 amino acid domain of the cdk inhibitor p21 is sufficient to bind PCNA and block DNA replication. Nucleic Acid Res., 24, 1724-1733 (1996). 

 

179. V. Dötsch, R. E.  Oswald and G. Wagner: Water suppression by coherence selection with absorptive lineshape without loss in sensitivity. J. Magn. Reson., B 108, 285-288 (1995).

 

180. K.T. Dayie and G. Wagner: Carbonyl carbon relaxation rates reveal a dynamic heterogeneity of the polypeptide backbone in villin 14T, J. Magn. Reson., B 109, 105-108 (1995).

 

181. G. Wagner, D.F. Wyss, J.S Choi, A. R. N. Arulanandam, E. L. Reinherz, and A. Krezel, R. A. Lazarus:  NMR Studies of Proteins Involved in Cell Adhesion Processes, in "NMR as a structural tool for macromolecules: Current status and future directions", M.D. Kemple and B.D.N Rao, eds. Kluwer, New York, 1996.

 

182. L.C. Myers, G. Wagner, G.L. Verdine: Direct Activation of the Methyl Chemosensor Protein N-Ada by CH3I. J. Am. Chem. Soc., 117, 10749-10750  (1995).

 

183. J.W. Peng, G. Wagner: The Frequency Spectrum of NH Bonds in Eglin c From Spectral Density Mapping at Multiple Fields, Biochemistry, 34, 16733-16752 (1995).

 

184. M.A. Markus, K. T. Dayie, P. Matsudaira, G. Wagner: Local mobility within villin 14T probed via heteronuclear relaxation measurements and a reduced spectral density mapping. Biochemistry, 35, 1722-1732 (1995).

 

185. E. Kupce, G. Wagner: Wideband homonuclear decoupling in proteins. J. Magn. Reson.,    B 109, 329-333 (1995).

 

186. G. Wagner, D.F. Wyss, J.S Choi, J. Li, A. Somlyar, A. R. N. Arulanandam, M.H. Knoppers, K.J. Willis and E. L. Reinherz:  Conformation, mobility and function of the N-linked glycan in the adhesion domain of human CD2. in "Dynamics and the Problem of Recognition in Biological Macromolecules", O. Jardetzky and J.-F. Lefèvre, eds. Plenum Press, New York, 1996, pp. 257-266 (1996).

 

187. V. Dötsch, R. E.  Oswald and G. Wagner: Amino acid type selective triple resonance experiments. J. Magn. Reson., B 110, 107-111 (1996).

 

188. H. Matsuo, H. Li and G. Wagner: A Sensitive HN(CA)CO Experiment for Deuterated Proteins. J. Magn. Reson., B 110, 112-115 (1996).

 

189. K. Moffat and G. Wagner: Biophysical methods, editorial overview. Curr. Opin. Struct. Biol. 5, 637-639 (1995).

 

190. J.-F Lefèvre, K. T.  Dayie, J. W. Peng  and G. Wagner: Internal Mobility in the Partially Folded DNA Binding and Dimerization Domains of GAL4: NMR Analysis of the N-H Spectral Density Functions. Biochemistry, 35, 2674-2686 (1996).

 

191. V. Dötsch, R. E.  Oswald and G. Wagner: Selective identification of threonine, valine and isoleucine sequential connectivities with a TVI-CBCACONH experiment. J. Magn. Reson., B 110, 304-308 (1996).

 

192. K. T. Dayie, G. Wagner and J.-F. Lefèvre: Theory and Practice of Nuclear Spin Relaxation in Proteins, Ann Rev. Phys. Chem., 47, 243-282 (1996). 

 

193. K. T. Dayie, G. Wagner and J.-F. Lefèvre: Heteronuclear relaxation and the experimental determination of the spectral density function.  in "Dynamics and the Problem of Recognition in Biological Macromolecules", O. Jardetzky and J.-F. Lefèvre, eds. Plenum Press, New York, 1996, pp. 139-162 (1996).

 

194. E. Kupce, G. Wagner: Multi-site band-selective decoupling in proteins. J. Magn. Reson., B 110, 309-312 (1996).

 

195. H. Matsuo, E. Kupce,  H. Li and G. Wagner: Use of Selective Ca Pulses for Improvement of HN(CA)CO-D and HN(COCA)NH-D Experiments, J. Magn. Reson., B 111, 194-198 (1996).

 

196. V. Dötsch and G. Wagner: Editing for amino acid type in CBCACONH experiments based on the  13Cb-13Cg coupling, J. Magn. Reson., B 111, 310-313 (1996).

 

197. D. Wyss and G. Wagner: Structural role of sugars in glycoproteins. Curr. Opin. Biotechnology, 7,  409-416 (1996).

 

198. V. Dötsch, H. Matsuo and G. Wagner: Amino acid type identification for deuterated proteins with a b-carbon edited HNCOCACB experiment. J. Magn. Reson., B 112, 95-100 (1996).

 

199. S. Talluri and G. Wagner: An optimized 3D NOESY-HSQC, J. Magn. Reson., B 112, 200-205 (1996).

 

200. H. Matsuo, E. Kupce,  H. Li and G. Wagner: Increased sensitivity in HNCA and HN(CO)CA experiments by selective Cb decoupling. J. Magn. Reson., B 113, 91-96 (1996).

 

201. H. Matsuo, E. Kupce and G. Wagner: Resolution and Sensitivity Gain in HCCH-TOCSY Experiments by Homonuclear Cb Decoupling. J. Magn. Reson., B 113, 190-194 (1996).

 

202. E.L. Reinherz, J. Li, A. Smolyar, D.F. Wyss, M.H. Knoppers, K.J. Willis, A.R.N. Arulanandam, J.S. Choi, G. Wagner: CD2: An exception to the immunoglobulin superfamily concept. Science 273, 1242 (1996).

 

203. K. J. Walters, H. Matsuo and G. Wagner: A simple method to distinguish intermonomer nuclear Overhauser effects in homodimeric proteins with C2 symmetry. J. Am. Chem. Soc., 119, 5958-5959 (1997).

 

204. I. Najfeld, K.T. Dayie, G. Wagner, T.F. Havel: A robust method for estimating cross-relaxation rates from simultaneous fits to build-up and decay curves. J. Magn. Reson., 124, 372-382 (1997).

 

205. S.A. Wolfe, P. Zhou, V. Dötsch, L. Chen, A. You, S. S. Ho, G.R. Crabtree, G. Wagner, G.L. Verdine: A novel Rel architecture in the DNA binding domain of human NFATc. Nature, 385, 172-176 (1997).

 

206. D.F. Wyss, K.T. Dayie and G. Wagner: The counterreceptor binding site of human CD2 exhibits an extended surface patch with slow motions in the μs -ms range. Protein Science, 6, 534-542 (1997).

 

207. J. Johnson, E. Meiering, J.l Wright, J.E. Pardo, A. Rosowsky and G. Wagner: NMR Solution Structures of the Antitumor Compound PT523 and NADPH in the Ternary Complex with Human Dihydrofolate Reductase. Biochemistry, 36, 4399-4411 (1997).

 

208. P. Schmieder, A.S. Stern, G. Wagner, J. Hoch, Quantification of Maximum entropy spectrum reconstructions: J. Magn. Reson. 125, 332-339 (1997).

 

209. M. A. Markus, P. Matsudaira and G. Wagner: Refined structure of villin 14T - Comparison with other actin-severing domains. Protein Science, 6, 1197-1209 (1997). 

 

210. K.T. Dayie and G. Wagner: Carbonyl Carbon Probe of Local Mobility in 13C,15N-Enriched Proteins Using High Resolution NMR. J. Am. Chem. Soc., 119, 7797-7806 (1997). 

 

211. P. Zhang, K.T. Dayie, G. Wagner: Unusual Lack of Internal Mobility And Fast Overall Tumbling in Oxidized Flavodoxin from Anacystis nidulans.  J. Mol. Biol., 272, 443-455 (1997).

 

212. J. L. Feltham, V. Dötsch, S. Raza, D. Manor, R. A. Cerione, M. J. Sutcliffe, G. Wagner, and R. E. Oswald: Definition of the Switch Surface in the Solution Structure of Cdc42Hs. Biochemistry, 36, 8755-8766 (1997). 

 

213. A.S. Carroll, D.E. Gilbert, X.Liu, J.W. Cheung, J. E. Michnowicz, G. Wagner, T.E. Ellenberger, T. K. Blackwell: SKN-1 domain and basic region monomer stabilization upon DNA binding. Genes and Development, 11, 2227-2238 (1997).

 

214. K. Walters, K.T. Dayie, R. Reece, M. Ptashne, G. Wagner: Structure and mobility of the PUT3 Dimer. Nature Structural Biol., 4, 744-750 (1997).

 

215. H. Matsuo, H. Li, A. M. McGuire, C. M. Fletcher, A.-C. Gingras, N. Sonenberg and G. Wagner: Structure of the translation factor eIF4E bound to m7GDP and interaction with 4E-binding protein. Nature Structural Biol., 4, 717-724 (1997).

 

216. E. Kupce, H. Matsuo, G. Wagner: Homonuclear decoupling in proteins. In “Biological Magnetic Resonance, Volume 16: Modern Techniques in Protein NMR” (N.R. Krishna & L.J. Berliner, eds.), pp. 149-193 (1999).

 

217. G. Wagner: An account of NMR in structural biology. Nature Structural Biol., 4, 841-844 (1997).

 

218. C.M. Fletcher, A.M. McGuire, H. Li, H. Matsuo, A.-C. Gingras, N. Sonenberg, G. Wagner: 4E binding proteins inhibit the translation factor eIF4E without folded structure, Biochemistry, 37, 9-15 (1998).

 

219. J.D. Baleja, V. Thanabal, G. Wagner: Refined solution structure of the DNA-binding domain of GAL4 and use of 3J(113Cd,1H) in structure determination. J. Biomol. NMR, 10, 397-401 (1997).

 

220. A.E. Ferentz, T. Opperman, G.C. Walker, G. Wagner: Dimerization of the UmuD’ protein in solution and its implications for regulation of SOS mutagenesis, Nature Structural Biol., 4, 979-983 (1997).

 

221. P. Zhou, L.J. Sun, V. Dötsch, G. Wagner, G.L. Verdine: Structural Basis for signal integration by NFATc. Cell, 92, 687-696 (1998).

 

222. A. M. McGuire, H. Matsuo, G. Wagner:  Internal and overall motions of the translation factor eIF4E: Cap binding and insertion in a CHAPS detergent micelle, J. Biomol. NMR, 12, 73-88 (1998).

 

223. S.E.Choe, P.T. Matsudaira, J. Osterhout, G. Wagner and E.I Shaknovich: Folding kinetics of villin 14T, a protein domain with a central b-sheet and two hydrophobic cores.  Biochemistry, 37, 14508-14518 (1998).

 

224. C.M. Fletcher, G. Wagner: The interaction of eIF4E with 4E-BP1 is an induced fit to a completely disordered protein.  Protein Science, 7, 1639-1642 (1998).

 

225. J. Zhu, F. Shibasaki, R. Price, J.-C. Guillemot, T. Yano, V. Dötsch, G. Wagner, P . Ferrara, F. McKeon: Intramolecular masking of nuclear import signal on NF-AT4 by casein kinase I and MEKK1. Cell, 93, 851-861 (1998).

 

226. J.J. Chou, H. Matsuo, H. Duan, G. Wagner: Solution Structure of the RAIDD CARD Domain and model for  CARD/CARD interaction in caspase-2 and caspase-9 recruitment, Cell, 94, 171-180 (1998).

 

227. E. Kupce, P. Schmidt, M. Rance, G. Wagner: Adiabatic mixing in the liquid state: J. Magn. Reson., 135, 361-367 (1998).

 

228. V. Dötsch, G. Wagner: New Approaches to Structure Determination by NMR, Curr. Opin. Struct. Biol., 8, 619-623 (1998).

 

229. A. Jasanoff, G. Wagner, D.C. Wiley: Structure of a trimeric domain of the MHC class II-associated chaperonin and targeting protein Ii, EMBO J. 17, 6812-6818 (1998).

 

230. K. Nishizawa, C. Freund, J. Li, G. Wagner, E.L. Reinherz: Identification of  a novel proline-binding motif regulating CD2-triggered T-lymphocyte activation, Proc. Natl. Acad. Sci. 95, 14897-14902 (1998).

 

231. G. Wagner, H. Matsuo, H. Li, C.M. Fletcher, A.M. McGuire, A.-C. Gingras, N. Sonenberg: Intermolecular interactions of proteins involved in the control of gene expression. in "Application of NMR to the Study of Structure and Dynamics of Supramolecular Chemistry", M. Pons (ed.), Kluwer Academic Publishers, Dordrecht, The Netherlands, pp. 247-254, 1999.

 

232. B. J. Hare, D.F. Wyss, M. S. Osburne,  P. S. Kern,  E.L. Reinherz, G. Wagner: Structure, Specificity and CDR Mobility of a Class II Restricted Single-Chain T-cell Receptor. Nature Str. Biol., 6, 574-581 (1999).

 

233. Z-Y. J. Sun, V. Dötsch, M. Kim, J. Li, E.L. Reinherz, G. Wagner: Functional glycan-free adhesion domain of human CD58: Design, production, and NMR structural studies, EMBO J., 18, 2941-2949 (1999).

 

234. J. J. Chou, H. Li, G. S. Salvesen, J. Yuan, and G. Wagner Solution Structure of BID, an Intracellular Amplifier of Apoptotic Signaling, Cell, 96, 615-624 (1999).

 

235. C. Freund, V. Dötsch, K. Nishizawa. E. Reinherz , G. Wagner: The GYF domain is a novel structural fold that is involved in lymphoid signaling through proline-rich sequences.  Nature Str. Biol., 6, 656-660 (1999).

 

236. C.M Fletcher, T.V. Pestova, C.U.T. Hellen, G. Wagner: Structure and interactions of the translation initiation factor eIF1, EMBO J., 18, 2631-2637 (1999).

 

237. P.E.C.Hershey, J. Gross, S. McWhirter, T. Alber, G. Wagner, A.B. Sachs: The cap binding protein eIF4E induces folding of a functional domain of yeast translation initiation factor eIF4G1,  J. Biol. Chem. 274, 21297-304 (1999).

 

238. Y. Lin, C. M. Fletcher, J. Zhou,  C. D. Allis,  G. Wagner: Solution structure of the catalytic domain of Tetrahymena GCN5 histone acetyltransferase in complex with coenzyme A, Nature, 400, 86-89 (1999).

 

239. J.-H. Wang, A. Smolyar, K. Tan, M. Kim, Z.-y. J. Sun, G. Wagner, E. L. Reinherz: Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counter receptors, Cell, 97, 791-803 (1999).

 

240. K. J. Walters, G. T. Gasser, S. J. Lippard, G. Wagner: Structure of the soluble monooxygenase regulatory protein B. Proc. Natl. Acad. Sci., 96, 7877-7882 (1999).

 

241. Y. Lin, G. Wagner: Efficient side-chain and backbone assignment in large proteins: Application to tGCN5, J. Biomol. NMR, 15, 227-239 (1999).

 

242. F. del Río-Portilla, A. Gaskell, D. Gilbert, J.A.A. Ladias, G. Wagner: Solution structure of hRPABC14.4, an essential subunit of human RNA polymerases I, II and III, Nature Str. Biol., 6, 1039-1042 (1999).

 

243. J. L. Battiste, T. V. Pestova, C. U. T. Hellen, G.Wagner: eIF1A Solution Structure Reveals a Large RNA-Binding Surface Important for Scanning Function, Mol. Cell, 5, 109-119 (2000).

 

244. H. Matsuo, K. J. Walters, K. Teruya, T. Tanaka, G. T. Gasser, S. J. Lippard, Y. Kyogoku, G. Wagner: Identification by NMR of residues at contact surfaces in large, slowly exchanging complexes, J. Am. Chem Soc, 121, 9903-9904 (1999).

 

245. B. J. Hare, G. Wagner: Application of automated NOE assignment to the three-dimensional structure refinement of a 28 kD single-chain T cell receptor. J. Biomol. NMR, 15, 103-113 (1999).

 

246. H. Matsuo, T. Moriguchi, T. Takagi, T. Kusakabe, S. Buratowski, M. Sekine, Y. Kyogoku, G. Wagner:  Efficient synthesis of 13C,15N labeled RNA containing the cap structure m7GpppA, J. Am. Chem Soc, 122, 2417-2421 (2000).

 

247. X. Luo, G. Fang, M. Coldiron, Y. Lin, M.W. Kirschner, H. Yu and G. Wagner: Structure of the Mad2 spindle assembly checkpoint protein and analysis of its interaction with Cdc20, Nature Str. Biol., 7, 224-229 (2000). 

 

248. A. Jasanoff, S. Song, A.R. Dinner, G. Wagner, D.C. Wiley: One of two unstructured domains of Ii becomes ordered in complexes with MHC class II molecules. Immunity 10, 761-768 (1999).

 

249. E.L. Reinherz, K. Tan, L. Tang, P. Kern, J.-h. Liu, Y. Xiong, R.E. Hussey, A. Smolyar, B. Hare, R. Zhang, A. Joachimiak, H.-C. Chang, G. Wagner, J.-h. Wang: The crystal structure of a CD4 lymphocyte-derived T-cell receptor in complex with peptide and MHC class II reveals an orthogonal docking mode. Science, 286, 1913-1921 (1999).

 

250. P. Zhou, J. Chou, R. S. Olea, J. Yuan, G. Wagner: Solution structure of Apaf-1 CARD and its interaction with caspase-9 CARD: A structural basis for specific adaptor/caspase interaction. Proc. Natl. Acad. Sci., 96, 11265-11270 (1999).

 

251. A.  Kitao and G. Wagner : A space-time structure determination of human CD2 reveals the CD58-binding mode. Proc. Natl. Acad. Sci., 97,  2064-2068 (2000).

 

252. A. A. Lugovskoy, P. Zhou, J. J. Chou, J. S. McCarty, Peng Li, G. Wagner: Solution structure of the CIDE-N-domain of CIDE-B and model for CIDE-N/CIDE-N interactions in DNA fragmentation pathways of apoptosis, Cell, 99, 747-755 (1999).

 

253. J. L. Battiste, G. Wagner: Utilization of Site-Directed Spin Labeling and High Resolution Heteronuclear NMR for Global Fold Determination of Large Proteins with Limited NOE Data, Biochemistry, 39, 5355-5365 (2000).

 

254. S.E.Choe, L. Li, P.T. Matsudaira,  G. Wagner and E.I Shaknovich: Differential stabilization of two hydrophobic cores in the transition state of the villin 14T folding reaction.J. Mol. Biol. 304, 99-115 (2000).

 

255. A.E. Ferentz, G. Wagner: NMR spectroscopy: A multifaceted approach to macromolecular structure. Quart. Rev. Biophys., 33, 29-65 (2000).

 

256. P. Hidalgo, A. Z. Ansari, P. Schmidt, B. Hare, N. Simkovic, S. Farrell, E.J. Shin, M. Ptashne and Gerhard Wagner: Recruitment of the Transcriptional Machinery through GAL11P: Structure and Interactions of the GAL4 Dimerization Domain, Genes & Development, 15, 1007-1020 (2001).

 

257. H. Kang, C. Freund, J.S. Duke-Cohan. A. Musacchio, G. Wagner, C.E. Rudd: SH3 domain recognition of a proline-independent tyorosine-based RKxxYxxY motif in immune cell adaptor SKAP55. EMBO J., 19, 2889-2899 (2000).

 

258. A. Degterev,  A. Lugovskoy, M. Cardone, B. Mulley, G. Wagner, T. Mitchison, J. Yuan. Identification of Small Molecule Inhibitors of BH3 and Bcl-xL interaction:  Nature Cell Biology, 3, 173-182 (2001).

 

259. K.S. Kim, Z.-Y.J. Sun, G. Wagner, E.L. Reinherz:  Heterodimeric CD3εγ extracellular domain fragments: production, purification and structural anaysis, J. Mol. Biol. 302, 899-916 (2000).

 

260. A. M. Krezel, J. S. Ulmer, G. Wagner, R.A. Lazarus: Recombinant decorsin: Dynamics of the RGD recognition site. Protein Sci. 9, 1428-1438 (2000).

 

261. Y. Lin, V. Dötsch, T. Wintner, K. Peariso, L. C. Myers, J. E. Penner-Hahn, G. L. Verdine, G. Wagner: Structural Basis for the Functional Switch of the E. Coli Ada Protein, Biochemistry, 40, 4261-4271 (2001).

 

262. P. Zhou, A. Lugovskoy, G. Wagner: A Solubility-Enhancement Tag (SET) for NMR Studies of Poorly Behaving Proteins. J. Biomol. NMR, 20, 11-14 (2001). 

 

263. P. Zhou, A. A. Lugovskoy, J. S. McCarty, Peng Li, G. Wagner: Solution Structure of DFF40 and DFF45 N-terminal Domain Complex and Mutual Chaperone Activity of DFF40 and DFF45. Proc. Natl. Acad. Sci., 98, 6051-6055 (2001).

 

264. D.P. Goldenberg, R.E. Kohn, D.E. Gilbert, G. Wagner: Solution structure and backbone dynamics of an w-conotoxin precursor. Protein Science, 10, 538-550 (2001).

 

265. J. L. Battiste, J. D. Gross, G. Wagner: Global fold determination of large proteins using site-directed spin labeling. . In “Biological Magnetic Resonance, Volume 17: Modern Techniques in Protein NMR” (N.R. Krishna & L.J. Berliner, eds.), 20, 79-101 (2003).

 

266. A. E. Ferentz, G. C. Walker and G. Wagner: Converting a DNA checkpoint effector (UmuD2C) into a lesion bypass polymerase (UmuD'2C), EMBO Journal, 20, 4287-4298 (2001).

 

267. Z.-Y.J. Sun, K.S. Kim, G. Wagner, E.L. Reinherz:  Mechanisms Contributing to T Cell Receptor Signaling and Assembly Revealed by the Solution Structure of an Ectodomain Fragment of the CD3epsilongamma Heterodimer, Cell, 105, 913-923 (2001).

 

268. K. J. Walters, A. E. Ferentz, B. J. Hare, P. Hidalgo, A. Jasanoff, H. Matsuo, G. Wagner: Experimental Approaches for Characterizing Protein-Protein Complexes and Oligomers by NMR Spectroscopy. In Methods in Enzymology , Nuclear Magnetic Resonance of Biological Macromolecules (eds. T.L. James, V. Dötsch, U. Schmitz) , 339B, 238-258 (2001).

 

269. C. Fan, H. Wang, S. Sun, G. Wagner, G. Li: Electron transfer reactivity and enzymatic activity of hemoglobin in a SP sephadex membrane. Anal. Chem., 73, 2850-2854 (2001).

 

270. C. Fan, G. Li, G. Wagner: Effect of Dimethyl Sulfoxide on the Electron Transfer Reactivity of Hemoglobin. Bioelectrochemistry, 54, 49-51 (2001).

 

271. C. Fan, Q. Gao, G. Li, D. Zhu, G. Wagner: An Unmediated Hydrogen Peroxide Biosensor Based on Hemoglobin Incorporated in a Montmorillonite Membrane. The Analyst, 126, 1086-1089 (2001).

 

272. C. Fan, H. Wang, G. Li, D. Zhu, G. Wagner: Incorporation of Horseradish Peroxidase in a Kieselguhr Membrane and the application to a Mediator-free Hydrogen Peroxide Sensor. Anal. Sci. 17, 273-276 (2001).

 

273. C. H. Lin, B. Hare, G. Wagner, S. C. Harrison, T. Maniatis,  E. Fraenkel: A small domain of CBP/p300 binds diverse proteins: solution structure and functional studies.  Molecular Cell 8, 581-590 (2001).

 

274. M. Kim , Z. Y. Sun , O. Byron , G. Campbell , G. Wagner , J.-H.Wang , E. L. Reinherz: Molecular dissection of the CD2-CD58 counter-receptor interface identifies CD2 Tyr86 and CD58 Lys34 residues as the functional "hot spot". J. Mol. Biol.  312, 711-720 (2001).

 

275. A. A. Lugovskoy, A. I. Degterev, A. F. Fahmy, P. Zhou, J. D. Gross, J. Yuan, G. Wagner:  A novel approach for characterizing protein ligand complexes: molecular basis for specificity of small-molecule Bcl-2 inhibitors,  J. Am. Chem. Soc., 124, 1234-1240 (2002).

 

276. A. Fahmy,  G. Wagner: TreeDock: A Tool  for Protein Docking Based on Minimizing van der Waals Energies,  J. Am. Chem. Soc., 124, 1241-1250 (2002).

 

277. K. J. Walters, M. F. Kleijnen, A. M. Goh, G. Wagner and P. M. Howley:  Structural studies of the interaction between ubiquitin family proteins and the proteasome subunit S5a. Biochemistry, 41, 1767-1777 (2002).

 

278. J. Müller, A. A. Lugovskoy, G. Wagner,  S. J. Lippard: NMR Structure of the [2Fe–2S] Ferredoxin Domain from Soluble Methane Monooxygenase Reductase and the Interaction with its Hydroxylase, Biochemistry, 41, 42-51 (2002).

 

280. J. D. Gross, H. Matsuo, M. Fletcher, A. B. Sachs, G. Wagner: Interactions of the Eukaryotic Translation Initiation Factor eIF4E. Cold Spring Harbor Symposium on Quantitative Biology:  The Ribosome, B. Stillman and D.J. Stewart, eds, Vol 66, 2001, pp. 397-402.

 

281. P. Dormitzer, Z.-Y. J. Sun, G. Wagner, S. C. Harrison:  The Rhesus Rotavirus VP4 Sialic Acid Binding Domain has a Galectin Fold with a Novel Carbohydrate Binding Site,  EMBO J.. 21, 885-897 (2002).

 

282. C. He, J.-C. Hus,  L. J. Sun, P. Zhou, D. P. G. Norman, V. Dötsch, H. Wei,  J. D. Gross, W. S. Lane, G. Wagner, G. L. Verdine: A Methylation-dependent Electrostatic Switch Controls DNA repair and Transcriptional Activation by E.coli Ada,  Molecular Cell, 20, 117-129 (2005).

 

283. S. J. Freedman,  Z.-Y. J. Sun,  F. Poy,  A. L. Kung,  D. M. Livingston,  G. Wagner,  M. J. Eck: Structural Basis for Recruitment of p300/CBP by Transcription Factor HIF-1, Proc. Natl.  Acad. Sci. USA. 99,  5367-5372 (2002).

 

284. P. Dormitzer, Z.-Y. J. Sun, O. Blixt, J. C. Paulson, G. Wagner, S. C. Harrison: The specificity of sialic acid binding by the rotavirus VP8* core, J. Virology, 76, 10512-10517 (2002). 

 

285. C. Freund, R. Kühne, H. Yang, E. L. Reinherz,  Gerhard Wagner: Dynamic interaction of CD2 with the GYF and  the SH3 domain of compartmentalized effector molecules, EMBO J., 21, 5985-5995 (2002).

 

286. J.D. Gross, V.M. Gelev, G. Wagner: A sensitive and robust method for obtaining intermolecular NOEs between side chains in large proteins, J. Biomol. NMR, 25, 235- 242 (2003).

 

287. D. Rovnyak, C. Filip, B. Itin, A.S. Stern, G. Wagner, R.G. Griffin, J.C. Hoch: Multiple quantum magic-angle spinning spectroscopy using non-linear sampling, J. Magn. Reson., 161, 43-55 (2003).

 

288. K. J. Walters, A. M. Goh, Q. Wang, G. Wagner, P.M. Howley, Ubiquitin family proteins and their relationship to the proteasome:  a structural perspective,   Biochemica et Biophysica Acta-Molecular Cell Research,  1695,  73-87 (2004).

 

289. A. Marintchev, V. G. Kolupaeva, T. V. Pestova,  G. Wagner: Mapping the binding interface between human eIF1A and eIF5B – a new interaction between old partners, Proc. Natl.  Acad. Sci. USA, 100, 1535-1540 (2003).

 

290. J.D. Gross, N.J. Moerke, T. Von der Haar, A. A. Lugovskoy, A.B. Sachs, J. McCarthy, and G. Wagner: Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E.  Cell,  115, 739-750 (2003). 

 

291. S.G. Hyberts, G. Wagner: IBIS – a tool for automated sequential assignment of protein spectra from triple resonance experiments, J. Biomol. NMR, 26, 335-344 (2003).

 

292. M. H. A. Roehrl, S. G. Hyberts, Z.-Y. J. Sun, A. P. Fields,  G. Wagner: Rapid backbone 1H, 13C, and 15N assignment of the V1 domain of human PKC iota using the new program IBIS, J. Biomol. NMR,  26, 373-374 (2003).

 

293. M. Kato, T. Ito, G. Wagner, C. C. Richardson, T. Ellenberger: Modular Architecture of the Bacteriophage T7 Primase Couples RNA Primer Synthesis to DNA Synthesis, Mol. Cell, 11, 1349-1360 (2003).

 

294. S. J. Freedman, Z.-Y. J. Sun, A. L. Kung, D. S. France, G. Wagner, M. J. Eck: Structural basis for negative regulation of hypoxia inducible factor-1a by CITED2,  Nature Struct. Biol. 10,  504-512 (2003).

 

295. C. Freund R. Kühne, S. Park, K. Thiemke E. L. Reinherz, G. Wagner:  Structural investigations of a GYF domain covalently linked to a proline-rich peptide, J. Biomol. NMR, 27, 143-149 (2003). 

 

296. P. Kim Z.-Y. J. Sun, S. C. Blacklow, G. Wagner, M.J. Eck: A Zinc Clasp Structure Tethers Lck to T-cell Coreceptors CD4 and CD8, Science,  301, 1725-1728 (2003).

 

297. A. E. Bennett,  J.D. Gross, G. Wagner: Broadband 13C-13C Adiabatic Mixing in Solution Optimized for High Fields, J. Magn. Reson.,  165,  59-79  (2003).

 

298. O. Gozani, P. Karuman, D. R. Jones, D. Ivanov,  J. Cha, A. A. Lugovskoy,  C. L. Baird, H. Zhu, S.F. Field, J. Villasenor, B. Mehrotra, J. Chen, V. R. Rao,  J. S. Brugge, C. G. Ferguson, B. Payrastre,  D. G. Myszka,  L. C. Cantley,  G. Wagner, N. Dievecha,  G. D. Prestwich,  J. Yuan: The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor,   Cell, 114, 99-111 (2003).

 

299. T. Ito,  G. Wagner:  Using codon optimization, chaperone co-expression, and rational mutagenesis for production NMR assignments of human eIF2 alpha. J. Biomol. NMR, 28, 357-367 (2004). 

 

300. S. Misaghi, Z.-Y. J. Sun, P. Stern, R. Gaudet, G. Wagner, H. Ploegh: A Structural and Functional Analysis of the Human Cytomegalovirus US3 Protein,  J. Virology,  78, 413-23 (2004).

 

301. M. H. A. Roehrl, S. Kang, J. Aramburu, A. Rao, G. Wagner , P. G Hogan: Selective inhibition of calcineurin-NFAT signaling by blocking protein-protein interaction with small organic molecules,  PNAS, 101, 7554-7559 (2004). 

 

302. I. B. Lomakin, V. G. Kolupaeva,  A. Marintchev,  G. Wagner,  T.V. Pestova : Position of eukaryotic initiation factor eIF1 on the 40S ribosomal subunit determined by directed hydroxyl radical probing, Genes & Development,   17, 2786-2797 (2003).

 

303. D. Rovnyak,  J.C. Hoch, A.S. Stern, G. Wagner: Resolution and Sensitivity  of High Field Nuclear Magnetic Resonance Spectroscopy,   J. Biomol. NMR, 30, 1-10 (2004).

 

304. G. Wagner.  NMR studies on the basic pancreatic trypsin inhibitor.  Magn. Reson. Chem. 41, S3-S15, 2003.

 

305. A. Natarajan,  N. Moerke, Y.-H. Fan, H. Chen, W. J. Christ, G. Wagner , J. A. Halperin . Synthesis of fluorescein labeled 7-methylguanosinemonophosphate. Bioorg.  Med.  Chem.  Lett.,  14, 2657-2660  (2004).

 

306.  Z.-Y. J. Sun, S. G. Hyberts, D. Rovnyak,  S. Park, A. S. Stern, J. C. Hoch,  G. Wagner: High-resolution aliphatic side-chain assignments in 3D HCcoNH experiments with joint H-C evolution and non-uniform sampling.  J. Biomol. NMR, 32, 55-60 (2005).

 

307. T. von der Haar,  J. D. Gross, G. Wagner , J. E. G. McCarthy: The mRNA cap-binding protein eIF4E in post-transcriptional gene expression,   Nature Struct. Mol. Biol.,  11, 503-511 (2004).

 

308. T. Ito, A. Marintchev,  G. Wagner: Solution structure of the alpha subunit of human eukaryotic initiation factor 2 reveals structural similarity to the guanine-nucleotide exchange factor eEF1B, Structure, 12, 1693-1704 (2004). 

 

309. D. Rovnyak,  D. Frueh, M. Sastry, Z.-Y. J. Sun, S. , J.C. Hoch, A.S. Stern, G. Wagner : Accelerated Acquisition of High Resolution Triple-Resonance Spectra Using Non-Uniform Sampling and Maximum Entropy Reconstruction ,  J. Magn. Reson., 170, 15-21 (2004).

 

310. Z.-Y. J. Sun, G. Wagner: 3D structure determination by NMR, in “Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine”, P. Schmieder and H. Oschkinat, eds., Springer Verlag, Heidelberg, 2004.

 

311. M. Kato, T. Ito, G. Wagner,  T. Ellenberger: A molecular handoff between bacteriophage T7 DNA primase and T7 DNA polymerase initiates DNA synthesis.  J Biol Chem, 279, 30554-30562 (2004).

 

312. L. D. Walensky,  A. L. Kung, I. Escher, T. J. Malia, S. Barbuto,1 R. Wright, G. Wagner, G. L. Verdine,  S. J. Korsmeyer: Activation of Apoptosis In Vivo by a Hydrocarbon-Stapled BH3 Helix, Science,  305, 1466-1470 (2004).

 

313. L.L. Chatwood,  J. Müller,  J.D. Gross, G. Wagner,  S.J. Lippard:  NMR structure of the flavin domain from soluble methane monooxygenase.  Biochemistry,  43, 11983-11991 (2004). 

 

314. D. Ivanov,  J. R. Stone, J. L. Maki, T. Collins,  G. Wagner:  Mammalian SCAN domain dimer is a domain-swapped homologue of  the HIV capsid  C-terminal domain,  Mol. Cell,  17, 137-143 (2005).

 

315. M. H. A. Roehrl  , J. Y. Wang,  G. Wagner: A General Framework for Development and Data Analysis of Competitive High-Throughput Screens for Small-Molecule Inhibitors of Protein-Protein Interactions by Fluorescence Polarization, Biochemistry,   43, 16056-16066 (2004).

 

316. M. H. A. Roehrl  , J. Y. Wang,  G. Wagner : Discovery of Small-Molecule Inhibitors of the NFAT-Calcineurin Interaction by Competitive High-Throughput Fluorescence Polarization Screening,  Biochemistry,  43, 16067-16075 (2004).

 

317. Z.-Y. J. Sun, S. T. Kim, I. C. Kim,  A. Fahmy,  E. L. Reinherz,  G. Wagner: Solution Structure Of The Cd3 εδ Ectodomain Fragment And Comparison With Cd3εγ As A Basis For Modeling T Cell Receptor Topology And Signaling, PNAS, 101, 16867-16872 (2004).

 

318. D. P. Frueh, T. Ito,  J.-S. Li, G. Wagner,  S. Glaser, N. Khaneja:  Sensitivity Enhancement in NMR of Macromolecules by Application of Optimal Control Theory,  J. Biomol. NMR, 32:23-30 (2005).

 

319. S. Park, R. Isaacson,  H. T. Kim, P. A. Silver, G. Wagner: Ufd1 exhibits the AAA-ATPase fold with two distinct ubiquitin interaction sites , Structure, 13,  995-1005 (2005).

 

320. M. A. Robinson, S. Park, Z.-Y. J. Sun, P. Silver, G. Wagner,  J. Hogle:  Multiple Conformations In The Ligand-Binding Site Of The Yeast Nuclear Pore Targeting Domain of Nup116p, J. Biol. Chem, 280, 35723-35732 (2005). 

 

321. M. H.A. Roehrl , G. J. Heffron, G. Wagner: Correspondence between spin-dynamic phases and pulse program phases of NMR spectrometers, J. Magn. Reson., 174, 325-330  (2005).

 

322. P. Cherepanov,  Z.Y.J. Sun, S. Rahman,  G.Wagner,  A. Engelman:  Solution structure of the HIV type 1 integrase-binding domain in LEDGF/p75,  Nat. Str. Mol. Biol, 12, 526-532 (2005).

 

323. S. K Elkin, D. Ivanov,  M. Ewalt,  C. G. Ferguson, S. G. Hyberts, Z.-Y. J. Sun, G. D. Prestwich,  J. Yuan, G. Wagner, M. A. Oettinger and O. Gozani: A PHD finger motif in the C-terminus of RAG2 modulates recombination activity,  J. Biol. Chem., 280,  28701-28710 (2005).

 

324. T. von der Haar, Y.  Oku, M. Ptushkina, N. Moerke, G. Wagner, J. D. Gross, J. E.G. McCarthy : Folding transitions during assembly of the eukaryotic mRNA cap-binding complex, J. Mol. Biol., 356, 982-992 (2006).

 

325. Y. Yamamoto,  C. R. Singh, A. Marintchev,  N. S. Hall, E. M. Hannig, G. Wagner, and K. Asano: The eukaryotic initiation factor (eIF) 5 HEAT domain mediates multifactor assembly and scanning with distinct interfaces to eIF1, eIF2, eIF3, and eIF4G. PNAS, 102, 16164-16169 (2005). 

 

326. M. Oberer, A. Marintchev,  G. Wagner : Structural basis for the enhancement of eIF4A helicase activity by eIF4G, Genes & Development, 19, 2212-2223 (2005).

 

327. G. Wagner:  Ending the prolonged life of cancer cells, Nature Chem. Biol., 1, 8-9 (2005).

 

328. D. P. Frueh,  H. Arthanari,  G. Wagner: Unambiguous assignment of NMR protein backbone signals with a time-shared triple-resonance experiment, J. Biomol. NMR, 33, 187-196 (2005). 

329. Z.-Y. J. Sun, D. P. Frueh, P. Selenko, J. C. Hoch, G. Wagner: Fast Assignment of 15N-HSQC Peaks using High-Resolution 3D HNcocaNH Experiments with  Non-Uniform Sampling, J. Biomol. NMR, 33, 43-50 (2005). 

 

330. A. Marintchev,  G. Wagner : eIF4G and CBP80 share a common origin and similar domain organization - implications for the eIF4G structure and function, Biochemistry, 44, 12265-12272 (2005).

 

331. N. J. Moerke, H. Aktas, H. Chen, S. Cantel, M. Y. Reibarkh, A. Fahmy, J. D. Gross, A. Degterev, J. Yuan, M. Chorev, J. A. Halperin, G. Wagner: Small Molecule Inhibition of the Interaction Between the Translation Initiation Factors eIF4E and eIF4G. Cell, 128, 257-267 (2007).

 

332. A. Natarajan, Y. Guo, H. Arthanari, G. Wagner, J. A. Halperin, M. Chorev: Synthetic Studies toward Aryl-(4-aryl-4H-[1,2,4]triazole-3-yl)-amine from 1,3-Diarylthiourea as Urea Mimetics. J Org Chem. 70, 6362-6368 (2005).

 

333. A. Marintchev, G. Wagner: Translation initiation: structures, mechanisms and evolution, Quart. Rev. Biophys, 37, 197-284 (2005).

 

334. M. Reibarkh, T. Malia, G. Wagner: NMR Distinction of Single and Multiple-Mode Binding of Small-Molecule Protein Ligands,  J. Am. Chem. Soc. 128, 2160-2161  (2006).

 

335. D. P. Frueh, D. A. Vosburg, C.T. Walsh, G. Wagner: Determination of all nOes in 1H-13C-Me-ILV-U-2H-15N proteins with two time-shared experiments, J. Biomol. NMR, 34, 31–40 (2006).

 

336.  S. Park, K. Takeuchi, G. Wagner: Solution structure of the first Src Homology 3 domain of human Nck2, J. Biomol. NMR, 34, 203-208 (2006). 

 

337. K. Takeuchi,  G. Wagner: NMR Studies of Protein Interactions, Curr. Opin. Struct. Biol., 16, 109–117 (2006).

 

338. A. Kitao, G. Wagner: Amplitudes and directions of internal protein motions from a JAM analysis of 15N relaxation data, Magn. Res. Chem., 44, S130-142 (2006).

 

339. D. P. Frueh, Z.Y. J. Sun, D. A. Vosburg, C.T. Walsh, G. Wagner: Non-uniformly sampled double-TROSY hNcaNH experiments for sequential assignments of large proteins, J. Am. Chem. Soc., 128, 5757-5763 (2006).

 

340. P. Selenko, G. Wagner: NMR mapping of protein interactions in living cells, Nature Methods, 3, 81-82 (2006).

 

341. F. Yang, B. W. Vought, J. S. Satterlee, Z.-Y. J. Sun, J. L. Watts, A. K. Walker, R. DeBeaumont, R. M. Saito, S. G. Hyberts, S. Yang, C. Macol, L. Iyer, R. Tjian, S. van den Heuvel, A. C. Hart, G. Wagner, A. M. Näär: An ARC/Mediator subunit required for SREBP gene activation and regulation of cholesterol and fatty acid homeostasis, Nature, 442, 700-704 (2006).

 

342. M. Reibarkh, T. Malia, G. Wagner: Identification of individual protein-ligand NOEs in the limit of intermediate exchange, J. Biomol. NMR, 36, 1-11 (2006).

 

343. M.-E. Bordeleau,  A. Mori, M. Oberer, L. Lindqvist, L. S Chard, T. Higa, G. J Belsham, G. Wagner, J. Tanaka & J. Pelletier: Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A, Nat. Chem. Biol., 2, 213-220 (2006).

 

344. P. Selenko, Z. Serber, B. Gadea, J. Ruderman, G. Wagner: Quantitative NMR analysis of the protein G B1 domain in Xenopus laevis egg extracts and oocyte cells, PNAS, 105, 11904-11909 (2006).

 

345. Philipp Selenko and Gerhard Wagner: Looking into live cells with in-cell NMR spectroscopy, J. Struct Biol. 158, 244-253 (2007).

 

346. V. Gelev, H. Aktas, A. Marintchev, T. Ito, D. Frueh, M. Hemond, D. Rovnyak, M. Debus, S. Hyberts, A. Usheva, J. Halperin and G. Wagner: Mapping of the Auto-Inhibitory Interactions of Protein Kinase R by Nuclear Magnetic Resonance, J. Mol. Biol., 364, 352–363 (2006).

 

347. Z. Serber, P. Selenko, R. Hänsel, S. Reckel, F. Löhr, J. E. Ferrell Jr., G. Wagner, V. Dötsch: Investigating macromolecules inside cultured and injected cells by in-cell NMR spectroscopy. Nature Protocols, 6, 2701-2709 (2006).

 

348. M. Sastry, C. Brown, G. Wagner, T.D. Clark: Cyclic peptide helices: A hybrid ß-hairpin/ß-helical supersecondary structure. J. Am. Chem. Soc. 128, 10650-10651 (2006).

349. S. A. McKenna, D. A. Lindhout, I. Kim, C. W. Liu, V. M. Gelev, G. Wagner, J. D. Puglisi: Molecular framework for the activation of PKR, J. Biol. Chem., 282, 11474-86 (2007).

 

350. Dmitri Ivanov, Oleg V. Tsodikov, Jeremy Kasanov, Tom Ellenberger, Gerhard Wagner & Tucker Collins: Domain-swapped dimerization of the HIV capsid C-terminal domain, PNAS, 104, 4353-4358 (2007).

 

351. T. Malia, G. Wagner: NMR Structural Investigation of the Mitochondrial Outer Membrane Protein VDAC and its Interaction with Anti-apoptotic Bcl-xL, Biochemistry, 46, 514-525 (2007).

 

352. T. Ito, G. Wagner: Resonance assignments of the subunit of human eukaryotic initiation factor 2 (heIF2). J. Biomol. NMR, 38, 173 (2007).

 

353. K. Takeuchi, E. Ng, T. Malia, G. Wagner: 14N, 1-13C amino acid selective labeling in a 2H15N background for NMR studies of large proteins, J. Biomol. NMR, 38, 89-98 (2007). 

 

354. M. Touma, Z.-Y. J. Sun,  L. K. Clayton, W. E. Marissen, A. M. Kruisbeek, G. Wagner, E. L. Reinherz: Importance of the CD3γ ectodomain terminal β-strand and membrane proximal stalk in thymic development, receptor assembly and function. J. Immunology, 178, 3668-79 (2007).

 

355. S. G. Hyberts, G. J. Heffron, N. G. Tarragona, K. Solanky, K. A. Edmonds, H. Luithardt, J. Fejzo, M.l Chorev, H. Aktas, K.Y. Colson, K. H. Falchuk, J. A. Halperin, G. Wagner: Ultra High Resolution 1H-13C HSQC Spectra of Metabolite Mixtures using non-linear sampling and Forward Maximum Entropy (FM) Reconstruction, J. Am. Chem. Soc, 129, 5108-516 (2007).

 

356. Léjard V, Brideau G, Blais F, Wagner G, Roehrl M, Duprez D, Rossert J. Scleraxis and NFATc contribute to COL1A1 expression in tendons. Matrix Biology 2006; 25: S73 Suppl.S.

 

357. G. Wagner, N. Moerke, H. Aktas, M. Chorev, J. Halperin: Small-molecule inhibitors of protein-protein interactions in translation initiation as potential anti-tumor agents. Am. Assoc. Cancer Res. Educ. Book, Apr 2007; 2007, 141 – 146 (2007). 

 

358. M. Reibarkh , Y. Yamamoto, C. Ranjit Singh, F. del Rio, A.Fahmy, B. Lee,  R. E. Luna, M. Li, G. Wagner, K. Asano:  Eukaryotic Initiation Factor (eIF)1 carries two distinct eIF5-binding faces important for multifactor assembly and AUG selection. J Biol. Chem. 283, 1094-1103 (January 2008).

 

359. Bordeleau ME, Cencic R, Lindqvist L, Oberer M, Northcote P, Wagner G, Pelletier J.: RNA-Mediated Sequestration of the RNA Helicase eIF4A by Pateamine A Inhibits Translation Initiation. Chem Biol. 13, 1287-95 (2006). 

 

360. O. V. Tsodikov, D. Ivanov, B. Orelli, L. Staresincic, O. D. Schärer, G. Wagner,  T. Ellenberger: Structural Basis for the Recruitment of ERCC1-XPF to Nucleotide Excision Repair Complexes by XPA, EMBO J. 26, 4768-4776 (2007).

 

361. K. Takeuchi, M.H.A. Roehrl, Z.-Y. J. Sun, G. Wagner: Structure of the Calcineurin-NFAT complex: Defining a T Cell Activation Switch Using Solution NMR and Crystal Coordinates. Structure, 16, 587-597 (2007), PMC1989110.

 

362. A. Marintchev, D. Frueh, G. Wagner : NMR methods for studying protein-protein interactions involved in translation initiation. In “Translation Initiation: Reconstituted Systems and Biophysical Methods. Methods in Enzymology, 430, 283-331 (2007).

 

363. T. D. Clark, M. Sastry, C.Brown, G.Wagner:  Solid-phase synthesis of backbone-cyclized β-helical peptides. Tetrahedron, 62, 9533-9540 (2006).

 

364. W. Zhong, Surjit B. Dixit, Robert J. Mallis, Haribabu Arthanari, Alexey A. Lugovskoy, David L. Beveridge, Gerhard Wagner and Ellis L. Reinherz: CTL recognition of a protective immunodominant influenza A virus nucleoprotein epitope utilizes a highly restricted Vb but diverse Va repertoire: Functional and structural implications, J. Mol. Biol. 372, 535-548 (2007).

 

365. Unbehaun, A, Marintchev, A, Lomakin, IB, Didenko, T, Wagner, G,  Hellen, CUT, Pestova, TV: Position of eukaryotic initiation factor eIF5B on the 80S ribosome mapped by directed hydroxyl radical probing, EMBO J, 26, 3109-3123 (2007).

 

366. Lejard V, Brideau G, Blais F, Salingcarnboriboon R, Wagner G, Roehrl MH, Noda M, Duprez D, Houillier P, Rossert JA.: Scleraxis and NFATc regulate the expression of the pro-alpha 1(I) collagen gene in tendon fibroblasts. J. Biol. Chem., 282, 17665 - 17675, (2007).

 

367. Z.-Y. J. Sun, K. J. Oh,  M. Kim,  M. Adamowicz, J. West, J. Yu, V. Brusic, Z. Qiao,  J.-h. Wang, G. Wagner, E. L. Reinherz: HIV-1 broadly neutralizing antibody extracts its epitope from a kinked MPER segment on the viral membrane, Immunity, 28, 52-63 (2008). 

 

368. D. P. Frueh, H. Arthanari, A. Koglin, D. Vosburg, A. E. Bennett, C. T. Walsh, and G. Wagner, Dynamic thiolation-thioesterase structure of a non-ribosomal peptide synthetase. Nature, 454, 903-906 (2008), PMC2597408.

 

369. A. Koglin, F. Löhr, F. Bernhard, V. Rogov, D. P. Frueh, P. Güntert, G. Wagner, C. T. Walsh, M. A. Marahiel and V. Dötsch: Structural basis for the selectivity of the external thioesterase of the surfactin synthetase. Nature, 454, 907-911 (2008). PMC2854587.

 

370. S. Kang, J. Kang, H. Kwon, D. Frueh, S. Hyun Yoo, G. Wagner, and S. Park: Effects of redox potential and Ca2+ on the inositol 1,4,5-trisphosphate receptor L3-1 loop region: implications for receptor regulation, J.Biol. Chem., 283, 25567-25575 (2008). PMC Journal - PMCID In Process.

 

371. C. Suzuki, R. Garces, K. Edmonds, S. Hiller, S. Hyberts, A. Marintchev, G. Wagner: PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains.  PNAS 105,3274-3279 (2008). PMC2265113

 

372. J. K. Thakur, H. Arthanari, F. Yang, S.-J. Pan, X. Fan, J. Breger, D. P. Frueh, K. Gulshan, D. Li, E. Mylonakis, K. Struhl, W. S. Moye-Rowley, B. P. Cormack, G. Wagner, A. M. Näär: A Nuclear Receptor-Like Pathway Regulating Multidrug Resistance in Fungi. Nature, 452, 604-609 (2008). 

 

373. P. Selenko, D. P. Frueh, S. J. Elsaesser, W. Haas, S. P. Gygi, G. Wagner: In situ observation of protein phosphorylation by high-resolution NMR spectroscopy. NSMB, 15, 321-329 (2008). 

 

374. A. Catic, Z.-Y. J Sun, D.M Ratner, S. Misaghi, E. Spooner, J. Samuelson, G. Wagner, H.L Ploegh: Sequence and structure evolved separately in a ribosomal ubiquitin variant. EMBO J. 26, 3474 - 3483 (2007). 

 

375. K. Takeuchi; H. Yang; E. Ng; S. Park; Z.-Y. J. Sun; Ellis L Reinherz; Gerhard Wagner: Structure of the CD3e-Nck complex and its role in TCR signaling and internalization. J. Mol. Biol., 380,704-716 (2008), PMC2577852. 

 

376. G. Wagner:  Introduction: NMR Resonance in Undergraduate Education.   Chapter 1, Modern NMR Spectroscopy in Education. D. Rovnyak, R. Stockland Jr. (eds.) American Chemical Society,Washington DC, (2007). 

 

377. Moerke N.J., Fahmy A., Degterev A., Harbinski F., Gross J.D., Aktas H., Halperin J.A., Wagner G. “Identification of small molecule inhibitors of eIF4E complex formation”, Clinical Cancer Research 9 (16): 6170S-6170S Part 2 Suppl. S, Dec. 2003.

 

378. H. Arthanari, D. Frueh, G. Wagner, B. Pryor, N. Khaneja: Fourier synthesis techniques for NMR spectroscopy in iomogenous fields. J. Chem. Phys, 128, 21503 (2008). PMC Journal - PMCID In Process.

 

379. L. Lindqvist, M. Oberer, M. Reibarkh, R. Cencic, M.-E. Bordeleau, E. Vogt, A. Marintchev, J. Tanaka, F. Fagotto, M. Altmann, G. Wagner, J. Pelletier: Selective Pharmacological Targeting of a DEAD box RNA helicase, PLoS ONE, 3, e1583 (2008). PMC2216682

 

380.  A. Degterev, J. Hitomi, M. Germscheid, I. Ch’en, O. Korkina, X. Teng, D. Abbott, G. D. Cuny, C. Yuan, G. Wagner, S. M. Hedrick, S. A. Gerber, A. Lugovskoy & J. Yuan: Identification Of Rip1 Kinase As A Specific Cellular Target Of Necrostatins. Nature Chem. Biol., 4, 313-321 (2008). PMC: Accepted for publication Mar. 6, 2008.

 

381. S. Hiller, R. G. Garces, T. J. Malia, V. Y. Orekhov, M. Colombini, G. Wagner: Solution structure of the integral human membrane protein VDAC-1 in detergent micelles, Science 321, 1206- 1210 (2008). PMC2579273.

 

382. A. Marintchev, K. A. Edmonds, B. Marintcheva, E. Hendrickson, M. Oberer, C. Suzuki, B. Herdy, N. Sonenberg, G. Wagner: The topology of the human eIF4A/4G/4H complex and the regulation of helicase activity, Cell, 136, 447-460. (2009), PMC2656774.

 

383. M. Hemond, T. L. Rothstein, G. Wagner: Fas Apoptosis Inhibitory Molecule (FAIM) contains a novel beta sandwich in contact with a partially ordered domain J. Mol. Biol., 386, 1024-1037 (2009). DOI: 10.1016/j.jmb.2009.01.004. PMC274528

 

384. S. T. Kim, K. Takeuchi, Z.-Y. J. Sun, M. Touma, C. E. Castro, A. Fahmy, V. P. Dave, D. J. Kappes, M. J. Lang, G. Wagner, E. L. Reinherz: The αβ T cell receptor is an anisotropic mechanosensor J. Biol.Chem. 284, 31028-31037 (2009).   PMC2781503

 

385. M. Billeter, G. Wagner, K. Wüthrich: Solution NMR structure determination of proteins revisited, J. Biomol. NMR, 42, 155-158 (2008), PMC2748914

 

386. K. Takeuchi, Z.-Y. J. Sun, G. Wagner: Alternate 13C-12C labeling for complete mainchain resonance assignments using C alpha direct-detection with applicability toward fast relaxing protein systems. J. Am. Chem. Soc., 130, 17210-17211 (2008), PMC2626166

 

387. J. K. Thakur, H. Arthanari, F. Yang, G. Wagner, A. M. Näär: Mediator subunit Gal11p/MED15 is required for fatty acid-dependent gene activation by yeast nuclear receptor-like transcription factor Oaf1p, JBC, 284, 4422-4428 (2009). PMC Journal – Free Article.

 

389. Y. Yoffe, M. Léger, A. Zinoviev, J. Zuberek, E. Darzynkiewicz, G. Wagner, M. Shapira: Evolutionary adaptation of the Leishmania eIF4F complex to cap-4 binding involves changes in the eIF4E-eIF4G interactions, Nucleic Acid Res, 37, 3243-3253, (2009) Epub 2009 Mar 24,  PMC2691829

 

389. L. Song, Z-Y. J. Sun, K. E. Coleman, M. Zwick, J. Gach, J.-H. Wang, E. L. Reinherz, G. Wagner, M. Kim: Broadly neutralizing anit-HIV-1 antibodies disrupt a hinge-related function of gp41 at the membrane interface. PNAS, 22, 9057-9062, (2009), PMC2690059

 

390. S. Hiller, H. Arthanari, G. Wagner: The T-lock: Automated compensation of radio-frequency induced sample heating. J.Biomol.NMR, 44 (2) 69-76 (2009).  PMC2733869

 

391. S. Hiller, G.Wagner: The role of solution NMR in the structure determinations of VDAC-1 and other membrane proteins. Curr. Opin. Struct. Biol., 19, 396-401 (2009). PMCID2739811

 

392. S. Hiller, I. Ibragimov, G. Wagner, V. Orekhov: Complete decomposition of four-dimensional NOESY spectra, J Am Chem Soc. 131, 12970-12978 (2009). PMC2771277

 

393. S. G. Hyberts, D. P. Frueh, H. Arthanari, G. Wagner: FM reconstruction of non-uniformly sampled protein NMR data at higher dimensions and optimization by distillation, J. Biomol. NMR, 45, 283-294 (2009). PMC2858293

 

394. D. P. Frueh, H. Arthanari, A. Koglin, C.T. Walsh, G. Wagner: A double TROSY hNCAnH experiment for efficient assignment of large and challenging proteins, J. Am. Chem. Soc., 131, 12880-12881 (2009).  PMC2749991

 

395. D. P. Frueh, A. Leed,  H. Arthanari, A. Koglin,  C. T. Walsh, G. Wagner: Time-shared HSQC-NOESY for accurate distance constraints measured at high-field in 15N-13C-ILV methyl labeled proteins, J. Biomol. NMR, 45, 311-318 (2009). PMC2778061

 

396. T. Raschle, S. Hiller, T.Y. Yu, A.J. Rice, T. Walz, G. Wagner: Structural and functional characterization of the integral membrane protein VDAC-1 in lipid bilayer nanodiscs. J Am Chem Soc. 131,17777-17779 (2009). PMC2793270

 

397 Wagner, G.: A topical issue: production and labeling of biological macromolecules for NMR investigations. J Biomol NMR 46, 1–2 (2010). Editorial.

 

398. Zhou P, Wagner: Overcoming the solubility limit with solubility-enhancement tags: successful applications in biomolecular NMR studies. J Biomol NMR 46, 23–31 (2010). PMC2879018

 

399. Takeuchi, K, Frueh, DP, Hyberts, SG, Sun, Z-Y, Wagner, G: High-resolution 3D CANCA NMR experiments for complete mainchain assignments using Ca direct-detection. J Am Chem Soc., 132, 2945-2951 (2010). PMC2832079

 

400. S.G. Hyberts, K. Takeuchi, G. Wagner: Poisson-Gap Sampling and FM Reconstruction for Enhancing Resolution and Sensitivity of Protein NMR Data. J Am Chem Soc., 132, 2945-2951 (2010). PMC2825045

 

401. Y. Yu, A. Marintchev, V.G. Kolupaeva,  A. Unbehaun, T. Veryasova, S.C. Lai, P. Hong, G. Wagner, C.U.Hellen, T.V. Pestova: Position of eukaryotic translation initiation factor eIF1A on the 40S ribosomal subunit mapped by directed hydroxyl radical probing. Nucleic Acid Res. 37, 5176-5182 (2009). PMC2731904

 

402. S. Hiller, J. Abramson, C. Mannella, G. Wagner, K. Zeth: The 3D structures of VDAC represent a native conformation. Trends Biochem. Sci., 35, 514-521 (2010). PMC2933295

 

403. K. Takeuchi, D. P. Frueh,  Z.-Y. J. Sun, S. Hiller, G. Wagner: CACA-TOCSY with alternate 13C-12C labeling: a 13Cα direct detection experiment for mainchain resonance assignment, dihedral angle information, and amino acid type identification. J. Biomol. NMR, 47, 55-63 (2010). PMC2868269

 

404. K. Takeuchi, Z.-Y. Sun, S. Park, G. Wagner: Auto-inhibitory interaction in multidomain adaptor protein Nck: possible roles in improving specificity and functional diversity, Biochemistry, 49, 5634-5641 (2010). PMC2899887

 

405. K. Takeuchi, G. Heffron,  Z.-Y.J. Sun, D.P. Frueh, G. Wagner: Nitrogen-detected CAN and CON experiments as alternative experiments for main chain NMR resonance assignments. J. Biomol. NMR, 47, 271-282 (2010). PMC2946331

 

406. S. Hiller, G. Wagner: Solution NMR Spectroscopy of Integral Membrane Proteins. Comprehensive Biophysics, Chapter 5.8: Solution NMR of Integral Membrane Proteins,

In: Edward H. Egelman, editor: Comprehensive Biophysics, Vol 5, Membranes, Lukas Tamm. Oxford: Academic Press, 2012. pp. 120-138.

 

407. S.T. Kim, M. Touma, K. Takeuchi, Z.-Y. Sun, V.P. Dave, D. J. Kappes, G. Wagner, E. L. Reinherz: Distinctive CD3 Heterodimeric Ectodomain Topologies Maximize Antigen-triggered Activation of αβ T Cell Receptors, J. Immunology, 185, 2951-2959 (2010). PMC2936104

 

408. M. G. Van der Heiden, J. W. Locasale, K. D. Swanson, H. Sharfi, G.J. Heffron, D. Amador-Noguez, H. R. Christofk, G. Wagner, J. D. Rabinowitz,  J. M. Asara, L. C. Cantley: Evidence for an alternative glycolytic pathway in rapidly proliferating cells. Science, 329 1492-1499 (2010). PMC3030121.

 

409. S. Kang, H. Kwon, H. Wen, Y. Song, D. Frueh, H.-C. Ahn, S. H. Yoo, G. Wagner, S. Park: Global dynamic conformational changes in the suppressor domain of IP3 receptor by stepwise binding of the two lobes of calmodulin. FASEB J., 25, 840-850 (2011). PMC Journal - In Process.

 

410. B. F. Shaw, H. Arthanari, M. Narovlyansky, A. Durazo, D. P. Frueh, M. P. Pollastri, A. Lee, B. Bilgicer, S. P. Gygi, G. Wagner, G. M. Whitesides: Neutralizing positive charges at the surface of a protein lowers its rate of amide hydrogen exchange without altering its structure or increasing its thermostability. J. Amer. Chem. Soc., 132,17411-17425 (2010) PMC3135700

 

411. K. Takeuchi, M. Gal, H. Takahashi, I. Shimada, G. Wagner: HNCA-TOCSY-CANH experiments with alternate 13C-12C labeling: a set of 3D experiment with unique supra-sequential information for mainchain resonance assignment. J. Biomol. NMR, 49, 17-26 (2011). PMC3072286

 

412. J.-S. Li, J. Ruths, T.-Y. Yu, H. Arthanari, G. Wagner: Optimal pulse design in quantum control: A unified computational method. PNAS, 108, 1879-1884 (2011) PMC Journal – Free Article.

 

413. A. G. Milbradt, M. Kulkarni, T. Yi, K. Takeuchi, Z.-Y. J. Sun, R. E. Luna, P. Selenko, A. M. Näär, G. Wagner: Structure of the VP16 Transactivator Target in ARC/Mediator, Nature Str. & Mol. Biology, 18, 410-415 (2011). PMC3076674

 

414. H. Arthanari, G. Wagner, N. Khaneja: Heteronuclear Decoupling by Multiple Rotating Frame Technique”, J. Magn. Reson., 209, 8-18 (2011). PMC3101322

 

415. S. G. Hyberts, H. Arthanari, G. Wagner:  Applications of non-uniform sampling and processing. Top. Curr. Chem., 316, 125-148 (2012).

 

416. T.  Raschle,  S. Hiller,  M. Etzkorn,  G. Wagner : Nonmicellar systems for solution NMR spectroscopy of membrane proteins. Curr Opin Struct Biol. 20, 471-479 (2010) PMC2928847

 

417. B. Miao, I. Skidan, J. Yang, A. Lugovskoy, M. Reibarkh, K.Long, T. Brazell, K.A. Durugkar, J. Maki, C. V. Ramana, B. Schaffhausen, G.Wagner, V. Torchilin, J.Yuan, A. Degterev: Small molecule inhibition of phosphatidylinositol-3,4,5-triphosphate (PIP3) binding to pleckstrin homology domains. PNAS, 107, 20126-20131 (2010). PMC2993381

 

418. C. A. Hoeffer, K. K. Cowansage, E.C. Arnold, J. L Banko, N. J. Moerke, R. Rodriguez, E. K. Schmidt, E. Klosi , M. Chorev, R. E. Lloyd, P. Pierre, G. Wagner, J. E. LeDoux, E. Klann: Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidation. PNAS, 108, 3383-3388 (2011). PMC3044415

 

419. A. Zinoviev, M. Léger, G. Wagner, M. Shapira: A novel 4E-interacting protein in Leishmania is involved in stage-specific translation pathways. Nucleic Acid Res, 39, 8404-8415 (2011). PMC Journal – Free Access.

 

420. C. Yi, I.-H. Jang, H. Pan, J. Seebacher, S. G. Hyberts, G. J. Heffron, M.G. Vander Heiden, R. Yang, F. Li, J. W. Locasale, H. Sharfi, B. Zhai, R. Rodriguez-Mias, H. Luithardt, L. C. Cantley, G. Q. Daley, J. M. Asara, S.P. Gygi, G. Wagner, C.-F. Liu, J. Yuan: Metabolic regulation of protein N-alpha-acetylation by Bcl-xL promotes cell survival, Cell, 146, 607-620 (2011).  PMC3182480

 

421. A. Fahmy, G. Wagner: Optimization of van Der Waals energy for protein side-chain placement and design. Biophysical J., 101, 1690-1698 (2011).  PMC 3183803.

 

422. B.F. Shaw, G. Schneider, H. Arthanari, M. Narovlyansky, D. Moustakas, A. Durazo, G. Wagner, G. Whitesides: Complexes of native Ubiquitin and dodecyl sulfate illustrate the nature of hydrophobic and electrostatic interactions in the binding of proteins and surfactants. JACS, 133, 17681-17695 (2011). [Epub ahead of print] PMID: 21939262

 

423. M. Kim, Z.-Y.J Sun, K. D. Rand, X. Shi, L. Song, Y. Cheng, A. F. Fahmy, S. Majumdar, G. Ofek, Y. Yang, P. D. Kwong, J.-H. Wang, J. R Engen, G. Wagner, E.L Reinherz: Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization. Nature Str. & Mol. Biology, 18, 1235-1234 (2011).

 

424. S.  Narayanan, H. Arthanari, M. Wolfe, G. Wagner: Molecular characterization of disrupted in schizophrenia-1 risk variant S704C reveals the formation of altered oligomeric assembly. J. Biol. Chem., (2011). published October 13, 2011 as doi:10.1074/jbc.M111.271593

 

425. M. Gal, K. A. Edmonds, A. G. Milbradt, K. Takeuchi, G. Wagner: Speeding up 15N detection: hCaN 2D NMR experiment. J. Biomol. NMR, 51, 497-504 (2011).

 

426. B.H. Aktas, J.A. Halperin, G. Wagner, M. Chorev: Inhibition of Translation Initiation as a Novel Paradigm for Cancer Therapy. Ann. Rep. in Med. Chem. 46, 189-210 (2011).

 

427. S. T. Kim, Y. Shin, K. Brazin, R. J. Mallis, J. Sun, G. Wagner, M.W. Lang, E. L Reinherz: TCR mechanobiology: Torques and tunable structures linked to early T cell signaling. Frontiers in T Cell Biology, 3:76. Epub (2012). PMID: 22566957 free PMC Article

 

428. S.G. Hyberts, A.G. Milbradt, A.B. Wagner, H. Arthanari, G. Wagner: Application of iterative soft thresholding for fast reconstruction of NMR data non-uniformly sampled with multidimensional Poisson Gap scheduling. J. Biomol. NMR, 52, 315-27 (2012).

 

429. R.E. Luna, H. Arthanari , H. Hiraishi, J. Nanda, P. Martin-Marcos, M. A. Markus, B. Akabayov, A. G. Milbradt, L. E. Luna, H.-C. Seo, S. G. Hyberts, A. Farmy, M. Reibarkh, D. Miles, P. R. Hagner, E. M. O’Day, T. Yi, A. Marintchev, A. Hinnebusch, J. Lorsch, K. Asano, G. Wagner: C-terminal domain of eukaryotic initiation factor 5 promotes start codon recognition by its dynamic interplay with eIF1 and eIF2β. Cell Reports, 1, 689–702, (2012). PMC3401385 FREE Journal.

 

430. K. Takeuchi, M. Gal, I. Shimada, G. Wagner: Low-γ Nuclei Detection Experiments for Biomolecular NMR, in Recent Developments in Biomolecular NMR, eds Marius Clore and Jennifer Potts, Royal Society of Chemistry, Cambridge, (2012), pp 25-52,  DOI: 10.1039/9781849735391-00025

 

431. T.-Y. Yu, T. Raschle, S. Hiller, G. Wagner: Solution NMR Spectroscopic Characterization of Human VDAC-2 in Detergent Micelles and Lipid Bilayer Nanodiscs. Biochim Biophys Acta. 1818,1562-1569 (2012). PMC3321126

 

432. M.T. Eddy, T.C. Ong, L. Clark, O. Teijido, P.C. van der Wel, R. Garces, G. Wagner, T.K. Rostovtseva, R.G. Griffin: Lipid dynamics and protein-lipid interactions in 2D crystals formed with the -barrel integral membrane protein VDAC1. J. Am. Chem. Soc. 134, 6375-6387 (2012). PMC333839.

 

433. L. Chen, B.H. Aktas, Y. Wang, X. He, R. Sahoo, N. Zhang, S. Denoyelle, E. Kabha, H. Yang, R.Y. Freedman, J.G. Supko, M. Chorev, G. Wagner, J.A. Halperin: Tumor suppression by small molecule inhibitors of translation initiation. Oncotarget 3, 869-881 (2012). Free Journal.

 

434. J.C. Schmidt, H. Arthanari, A. Boeszoermenyi, N. M. Dashkevich, E. M. Wilson-Kubalek, N. Monnier, M. Markus, M. Oberer, R. A. Milligan, M. Bathe5, G. Wagner, E.A. L. Grishchuk, I. M. Cheeseman: The kinetochore-bound Ska1 complex tracks depolymerizing microtubules by binding to curved protofilaments. Develop. Cell, Nov 13;23(5):968-80. doi: 10.1016/j.devcel.2012.09.012. Epub 2012 Oct 18. (2012)

 

435. P. Coote, H. Arthanari, T. Yu, A. Natarajan, G. Wagner, N. Khaneja: Pulse design for broadband correlation NMR spectroscopy by multi-rotating frames. J. Biomol. NMR, 55, 291-302 (2013) Feb 19. [Epub ahead of print]

 

436. S. G. Hyberts,  S.A. Robson, G. Wagner: Exploring signal-to-noise ratio and sensitivity in non-uniformly sampled multi-dimensional NMR spectra. J Biomol NMR. 55, 167-78 (2013) PMC3570699

 

437.  A. J. Wommack, S. A. Robson, Y. A. Wanniarahchi, A. Wan, C. J. Turner, G. Wagner, E. M. Nolan. NMR solution structure and condition-dependent oligomerization of the antimicrobial peptide human defensin 5. Biochemistry, 51, 9624-9634 (2012) PMC3579768

 

438. F. Hagn, M. Etzkorn, T. Raschle, G. Wagner: Optimized Phospholipid Bilayer Nanodiscs Facilitate High-Resolution Structure Determination of Membrane Proteins, JACS, 135, 1919-1925 (2013).  PMC3566289

 

439. M. Etzkorn, T. Raschle, F. Hagn, V. Gelev, A.T. Rice, T. Walz, G. Wagner: Cell-Free Expressed Bacteriorhodopsin in Different Soluble Membrane Mimetics: Biophysical Properties and NMR Accessibility, Structure, 21, 394-401 (2013) doi:pii: S0969-2126(13)00009-9. 10.1016/j.str.2013.01.005. [Epub ahead of print] PMID: 23415558, PMC3595385.

 

440. S. Akabyov, G. Wagner: Backbone resonance assignment of the HEAT1-domain of the human eukaryotic translation initiation factor 4GI, Biomol NMR Assign 8:89–91 (2014). [Epub ahead of print] PMID: 23325513, PMC3640741

 

441. B., S. R. Akabayov, S.–J. Lee, G. Wagner, C. C. Richardson: Impact of macromolecular crowding on DNA. Nature Communications  4, 1615, (2013). doi: 10.1038/ncomms2620.  NIHMSID 448127

 

442. T. Yi, E. Papadopoulos, P. Hagner, G. Wagner: HIF-1α promotes cap-dependent translation of selective mRNAs through upregulating eIF4E1 in breast cancer cells under hypoxia conditions. J. Biol. Chem., J. Biol. Chem. 288, 18732-18742 (2013). PMC3696647

 

443.  S. R. Akabayov, B. Akabayov, Charles C. Richardson, Gerhard Wagner:  Molecular crowding enhanced ATPase activity of the RNA helicase eIF4A correlates with compaction of its quaternary structure and association with eIF4G, JACS, 135 (27), 10040–10047 (2013). Epub June 27 (2013). PMID: 23767688

 

444. P. Martin-Marcos, J. Nanda, R. E. Luna, G. Wagner, J. R. Lorsch, and A. G. Hinnebusch: β-hairpin loop of eIF1 mediates 40S ribosome binding to regulate initiator tRNAMet recruitment and accuracy of AUG selection in vivo, J. Biol. Chem., 288, 27546-27562 (2013)

 

445. Z.-Y. J Sun, Y. Cheng, M.  Kim, L.  Song, J. Choi, U.  J. Kudah, V.  Brusic, B.  Chowdhury, L.  Yu, M. S. Seaman, G. Bellot, W.   M. Shih, G. Wagner; E. L. Reinherz: Disruption of helix-capping residues 671 and 674 reveals a role in HIV-1 entry for a specialized hinge segment of the membrane proximal external region of gp41. J. Mol. Biol., 426, 1095-1108 (2014). 

 

446.  Yi T, Zhai B, Yu Y, Kiyotsugu Y, Raschle T, Etzkorn M, Seo HC, Nagiec M, Luna RE, Reinherz EL, Blenis J, Gygi SP, Wagner G. Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells.  Proc Natl Acad Sci,  2014 May 27;111(21):E2182-90. doi: 10.1073/pnas.1404943111.  PMC4040611 

 

447. M. Gal, S. Li, K.Takeuchi: The LxVP and PxIxIT NFAT Motifs Bind Simultaneously to overlapping epitopes in Calcineurin’s catalytic domain CnA distant to the regulatory domain CnB, Structure, 22, 1016-1027 (2014) PMC4102887.

 

448. G. Wagner, W. Chiu: Exploring new limits in complex biological structures. Curr. Opin. Struct. Biol. 23, 704-706 (2013).

 

449.  S.G. Hyberts, H. Arthanari, S.A. Robson, G. Wagner: Perspectives in Magnetic Resonance: NMR in the Post-FFT Era. J. Magn. Reson, 241, 60-73 (2014). doi: 10.1016/j.jmr.2013.11.014..  PMCID: PMC3964371

 

450.  R. Luna, S.R. Akabayov, J.J. Ziarek, G. Wagner: Examining weak protein-protein interactions in start codon recognition via nuclear magnetic resonance spectroscopy, FEBS J. 2013 Nov 30. doi: 10.1111/febs.12667. [Epub ahead of print]

 

451. R. Luna, H. Arthanari, H. Hiraishi, B. Akabayov, L. Tang, C. Cox, M. Markus, L. Luna, Y. Ikeda, R. Watanabe, E. Bedoya, C. Yu, S. Alikhan, G. Wagner, K. Asano, The interaction between eukaryotic initiation factor 1A and  eIF5 retains eIF1 within scanning preinitiation complexes, Biochemistry, 52, 9510-8. (2013) doi: 10.1021/bi4009775. Epub 2013 Dec 19. PMID: 24319994 [PubMed - in process]

 

452. S. Elter, T. Raschle, S. Arens, A. Viegas. V. Gelev, M. Etzkorn, G. Wagner: The use of amphipols for NMR structural characterization of 7-TM proteins. J. Membr. Biol. May (2014).

 

453. A. Boeszoemenyi, J.C. Schmidt, I.M. Cheeseman, M. Oberer, G. Wagner, H. Arthanari: Resonance assignments of the microtubule-binding domain of the C. elegans spindle and kinetochore-associated protein 1. Biomol NMR Assign. (2013).

 

454. R. Yefidoff-Freedman, T. Chen, R. Sahoo, L. Chen, G. Wagner, J. A. Halperin, B. H. Aktas,  M. Chorev: 3-Substituted Indazoles as Configurationally Locked 4EGI-1 Mimetics and Inhibitors of the eIF4E/eIF4G Interaction. ChemBioChem, 15, 595-611 (2014).

 

455. K.A. Edmonds, G. Wagner: 1H, 13C, and 15N backbone and sidechain chemical shift assignments for the HEAT2 domain of human eIF4GI. J. Biomol. Assignments, Apr;9 (1):157-60 (2015).

 

456. K. N. Brazin, R. J. Mallis, C. Li, D. B. Keskin, H. Arthanari, Y.I Gao, S.-L. Wu, B. L. Karger, G. Wagner, E. L. Reinherz: Constitutively oxidized CxxC motifs within the CD3 heterodimeric ectodomains of the T cell receptor complex enforce the conformation of juxtaposed segments. JBC, 289, 18880-18892 (2014).

 

457. Y. Avnir, A. S. Tallarico, Q. Zhu, A. S. Bennett, G. Connelly, J. Sheehan, J. Sui, A. Fahmy, C.-y. Huang, G. Cadwell, L. A. Bankston, A.T. McGuire, L. Stamatatos, G. Wagner, R. C. Liddington, W. A. Marasco: Molecular Signatures of Hemagglutinin Stem-Directed Heterosubtypic Human Neutralizing Antibodies against Influenza A Viruses. PLOS Pathogens, 10 (5) e1004103 (2014).

 

458. P. Coote, K. Leigh, N. Khaneja, G. Wagner, H. Arthanari: A new broadband homonuclear mixing pulse for NMR with low applied power. J. Chem. Phys., 141, 024201 (2014). doi: 10.1063/1.4885853.

 

459. R. Linser, B. Bardiaux, L. Andreas, S. Hyberts, V. Morris, G. Pintacuda, M. Sunde, A. Kwan, G. Wagner: Solid-State NMR Structure Determination from Diagonal-Compensated Proton-Proton Restraints. JACS, 136, 11002-11010 (2014).

 

460. T. Yi, E. Kabha, E. Papadopoulos, G. Wagner: 4EGI-1 Targets Breast Cancer Stem Cells by Selective Inhibition of Translation that Persists in CSC Maintenance, Proliferation and Metastasis, Oncotarget, 5 (15), 6028-6037 (2014). Free PMC Article

 

 461. R. Linser, V. Gelev, F. Hagn, S.G.  Hyberts, G. Wagner: Selective methyl labeling of eukaryotic membrane proteins using cell-free expression, J. Am. Chem. Soc., 136, 11308-11310 (2014).

 

462. T. Yi, G. Wagner: Translation in Cancer and Hypoxia. In “Translation and its Regulation in Cancer Biology and Medicine” A. Parsyan Editor, Springer, Dordrecht, 20, 421- 434 (2014).

 

463. E. Papadopoulos, S. Jenni, E. Kabha, K. J. Takrouri, T. Yi, N. Salvi, R.E. Luna, E. Gavathiotis, P. Mahalingam, H. Arthanari, R. Rodriguez-Mias, R. Yefidoff Freedman, B. H. Aktas, M. Chorev, J. Halperin, G. Wagner: Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G. PNAS, Aug 5;111(31):E3187-95. doi: 10.1073/pnas.1410250111. Epub 2014 Jul 21.  PMC4128100.

 

464. Mahalingam P, Takrouri K, Chen T, Sahoo R, Papadopoulos E, Chen L, Wagner G, Aktas BH, Halperin JA, Chorev M.: Synthesis of rigidified eIF4E/eIF4G inhibitor-1 (4EGI-1) mimetic and their in vitro characterization as inhibitors of protein-protein interaction. J. Med. Chem. 57, 5094-5111 (2014). PMC4216204.

 

465. P. Ivanov, E. O’Day, M. M. Emara, G. Wagner, J. Lieberman, P. Anderson: G-quadruplex structures contribute to the neuroprotective effects of angiogenin-induced tRNA fragments. Proc Natl Acad Sci U S A. 2014 Nov 17. pii: 201407361. [Epub ahead of print], PMID: 25404306

 

466. K. Takeuchi, Z.-Y. J. Sun, S. Li, M. Gal, G. Wagner: NMR resonance assignments of the catalytic domain of human serine/threonine phosphatase calcineurin in unligated and PVIVIT-peptidebound states. Biomol NMR Assign. 2014 Sep 11. [Epub ahead of print], PMID: 25209144

 

467. S. R. Akabayov, B. Akabayov, G. Wagner: Human Translation Initiation Factor eIF4G1 Possesses a Low-Affinity ATP Binding Site Facing the ATP-Binding Cleft of eIF4A in the eIF4G/eIF4A Complex. Biochemistry. 2014 Oct 21;53(41):6422-5. doi:10.1021/bi500600m. Epub 2014 Oct 8. PMID: 25255371

 

468. P. Martin-Marcos, J.S. Nanda, R.E. Luna, F. Zhang, A.K. Saini, V.A. Cherkasova, G. Wagner, J.R. Lorsch, A.G. Hinnebusch: Enhanced eIF1 binding to the 40S ribosome impedes conformational rearrangements of the preinitiation complex and elevates initiation accuracy. RNA. 2014 Feb;20(2):150-67. doi: 10.1261/rna.042069.113. Epub 2013 Dec 13.PMID: 24335188

 

469. D. K. Das, Y. Feng, R. J. Mallis, X. Li, D. B. Keskin, R. E. Hussey, S. K. Brady, J.-h. Wang, G. Wagner, E.L. Reinherz, Matthew J. Lang: A force-dependent transition in the T cell receptor β subunit allosterically regulates peptide discrimination and pMHC bond lifetime. Proc Natl Acad Sci U S A. 112:1517-1522. (2015) PMID: 25605925

 

470. M.T. Eddy, L. Andreas, O. Teijido, Y. Su, L. Clark, S. Y. Noskov, G. Wagner, T. K. Rostovtseva, R. G. Griffin: Magic Angle Spinning Nuclear Magnetic Resonance Characterization of Voltage-Dependent Anion Channel Gating in Two-Dimensional Lipid Crystalline Bilayers, Biochemistry. Biochemistry, 54, 994−1005 (2015)

 

471. R. Kaptein, G. Wagner: NMR studies of membrane proteins. J.Biomol. NMR, 61, 181-184 (2015).

 

472. F. Hagn, G. Wagner: Structure Refinement and Membrane Positioning of Selectively Labeled OmpX in Phospholipid Nanodiscs. J Biomol NMR. 61, 249-260 (2015). 

 

473. A. G. Milbradt, H. Arthanari, K. Takeuchi, A. Boeszoermenyi, F.Hagn, G. Wagner: Increased Resolution of Aromatic Cross Peaks Using Alternate 13C Labeling and TROSY. J. Biomol. NMR, 62, 291-301 (2015)

 

474. T. Yi, H. Arthanari, B. Akabayov, H. Song, H. Qi, M. Jedrychowski, E. Papadopoulos, R. Luna, S. P. Gygi, S. A. Huang and G. Wagner: Regulation of DICER-independent miRNA biogenesis and RISC mediated gene silencing by eIF1A, Nat Commun. 2015 May 28;6:7194. doi: 10.1038/ncomms8194.PMID: 26018492 (2015).

 

475.  E. O’Day, M.T.N. Le, S. Imai, S. M. Tan, R. Kirchner, H. Arthanari, O. Hofmann, G. Wagner, J. Lieberman: An RNA-binding protein, Lin28, recognizes and remodels G-quartets in the miRNAs and mRNAs it regulates, J Biol Chem. 290, 17909-17922 (2015).  PMID: 26045559

 

476. R. J. Mallis, K. Bai, H. Arthanari, R. E. Hussey, M. Handley, Z. Li, L. Chingozha, J. S. Duke-Cohan, H. Lu, J.-H. Wang, C. Zhu, G. Wagner, E.L. Reinherz: Pre-T cell receptor ligand binding impacts thymocyte development prior to αβTCR expression. Proc Natl Acad Sci U S A. 2015 Jun 8. pii: 201504971. [Epub ahead of print] PMID: 26056289

 

477.  K. Takrouri, T. Chen, E. Papadopoulos, R. Sahoo. E. Kabha, H. Chen, S. Cantel, G. Wagner, J.A. Halperin, B.H. Aktas, M. Chorev: Structure-activity relationship study of 4EGI-1, small molecule eIF4E/eIF4G protein-protein interaction inhibitors. Eur. J. Med. Chem. 77, 361-377 (2014).

 

478. N. Sekiyama, H. Arthanari, E. Papadopoulos, R. Rodriguez-Mias, G. Wagner, M. Léger-Abraham: Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1. PNAS, Jul 28;112(30):E4036-4045 (2015).

 

479. A. Boeszoermenyi, H. M. Nagy , H. Arthanari, C. J. Pillip, H.  Lindermuth, R. Luna, G. Wagner, R. Zechner, K. Zangger, M. Oberer: Structure of a CGI-58 Motif Provides the Molecular Basis of Lipid Droplet Anchoring. J. Biol. Chem., 290, 26361-72 (2015).

 

480. R. Linser, N. Salvi, R.Briones, P. Rovó, B.de Groot, G. Wagner: The Membrane Anchor of the Transcriptional Activator SREBP is Characterized by Intrinsic Conformational Flexibility. Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):12390-5. doi: 10.1073/pnas.1513782112. Epub 2015 Sep 21. PMID: 26392539

 

481. T. Raschle, C. Lin, R. Jungmann, W.M. Shih, G. Wagner: Controlled co-reconstitution of multiple membrane proteins in lipid bilayer nanodiscs using DNA as a scaffold. ACS Chemical Biology, 10, 2448-2454 (2015) 

       doi http://dx.doi.org/10.1021/acschembio.5b00627.

 

482. R. J. Mallis, E. L.Reinherz, G.Wagner, H. Arthanari: Backbone resonance assignment of N15, N30 and D10 T cell receptor b subunits. J. Biomol  NMR Assign. 2016 Apr;10(1):35-9. doi: 10.1007/s12104-015-9632-0.  PMC4767692.

 

483. K. Takeuchi, H. Arthanari, I. Shimada, G. Wagner: Nitrogen detected TROSY at high field yields high resolution and sensitivity for protein NMR J. Biomol NMR, 63, 323-331 (2015). PMID: 26497830.

 

484.  W. Nartey, S. Basak, N. Kamariah, M.S.S. Malathy, S. Robson, G. Wagner, B. Eisenhaber, F. Eisenhaber, G. Grüber: NMR studies reveal a novel grab and release mechanism necessary for efficient catalysis of the bacterial 2-Cys peroxiredoxin machinery. FEBS J., 2015 Sep 24. doi: 10.1111/febs.13522. [Epub ahead of print]

 

485. Hiller S, Malia TJ, Garces RG, Orekhov VY, Wagner G.: Backbone and ILV side chain methyl group assignments of the integral human membrane protein VDAC-1. Biomol NMR Assign. 2010 Apr;4(1):29-32. doi: 10.1007/s12104-009-9194-0. Epub 2009 Nov 22. PMID: 20437141, PMCID: PMC2896003.

 

486. Nishikawa, JL, Boeszoermenyi, A,Vale-Silva, LA, Torelli, R, Posteraro, B, Sohn YJ, Gelev,V, Sanglard, D, Sanguinetti, M, Buhrlage, SJ, Gray, NS, Wagner, G, Näär, AM, and Arthanari, H.: Inhibiting Fungal Multidrug Resistance by Disrupting an Activator-Mediator Interaction, Nature. 2016 Feb 25;530(7591):485-9. doi: 10.1038/nature16963. Epub 2016 Feb 17.PMID: 26886795. 

 

487. A. Viegas, T. Viennet, T.-Y. Yu, F. Schumann, W. Bermel, G. Wagner, M. Etzkorn: UTOPIA NMR: Recovering lost magnetization using interleaved low-gamma detection, J Biomol NMR. 64, 9-15 (2016) Jan 4. [Epub ahead of print] PMID: 26728075, PMC4947531 

 

488. K. Takeuchi, H. Arthanari, M. Imai, G. Wagner, I. Shimada: Nitrogen-detected TROSY yields comparable sensitivity to proton-detected TROSY for non-deuterated, large proteins under physiological salt conditions. J. Biomol. NMR 64, 143-151 (2016).

 

489. Marintcheva B, Marintchev A, Wagner G, Richardson CC. Acidic C-terminal tail of the ssDNA-binding protein bacteriophage T7 and ssDNA compete for the same binding surface. Proc Natl Acad Sci U S A. 2008 Feb12;105(6):1855-60. PubMed PMID: 18238893; PubMed Central PMCID: PMC2538852.

 

490. Locasale JW, Grassian AR, Melman T, Lyssiotis CA, Mattaini KR, Bass AJ, Heffron G, Metallo CM, Muranen T, Sharfi H, Sasaki AT, Anastasiou D, Mullarky E, Vokes NI, Sasaki M, Beroukhim R, Stephanopoulos G, Ligon AH, Meyerson M, Richardson AL, Chin L, Wagner G, Asara JM, Brugge JS, Cantley LC, Vander Heiden MG. Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis. Nat Genet. 2011 Jul 31;43(9):869-74. doi: 10.1038/ng.890. PubMed PMID: 21804546; PubMed Central PMCID: PMC3677549.

 

491. Kim M, Song L, Moon J, Sun ZY, Bershteyn A, Hanson M, Cain D, Goka S, Kelsoe G, Wagner G, Irvine D, Reinherz EL. Immunogenicity of membrane-bound HIV-1 gp41 membrane-proximal external region (MPER) segments is dominated by residue accessibility and modulated by stereochemistry. J Biol Chem. 2013 Nov 1;288(44):31888-901. doi: 10.1074/jbc.M113.494609. Epub 2013 Sep 18. PubMed PMID: 24047898; PubMed Central PMCID: PMC3814781.

 

492. Wommack AJ, Ziarek JJ, Tomaras J, Chileveru HR, Zhang Y, Wagner G, Nolan EM. Discovery and characterization of a disulfide-locked C(2)-symmetric defensin peptide. J Am Chem Soc. 2014 Oct 1;136(39):13494-7. doi: 10.1021/ja505957w. Epub 2014 Sep 23. PubMed PMID: 25181039; PubMed Central PMCID: PMC4183617.

 

493. Hiraishi H, Oatman J, Haller SL, Blunk L, McGivern B, Morris J, Papadopoulos E, Gutierrez W, Gordon M, Bokhari W, Ikeda Y, Miles D, Fellers J, Asano M, Wagner G, Tazi L, Rothenburg S, Brown SJ, Asano K. Essential role of eIF5-mimic protein in animal development is linked to control of ATF4 expression. Nucleic Acids Res. 2014;42(16):10321-30. doi: 10.1093/nar/gku670. Epub 2014 Aug 21. PubMed PMID: 25147208; PubMed Central PMCID: PMC4176352.

 

494. N. Salvi, E. Papadopoulos, M. Blackledge, G. Wagner: The role of dynamics and allostery in the inhibition of the eIF4E/eIF4G translation initiation factor complex. Angewandte Chemie, 55, 7176-7179 (2016). PMC5022372

 

495. D. Goricanec R. Stehle, P. Egloff, S. Grigoriu , A. Plückthun, G.Wagner , Franz Hagn: Conformational dynamics of a G-protein alpha subunit is tightly regulated by nucleotide binding. PNAS, 113, E3629-3638 (2016).  PMC4932968

 

496. K.N. Brazin, R.J.7, D.K. Das, Y. Feng, W. Hwang, J.H. Wang, G. Wagner,  M.J. Lang, E.L.Reinherz. Structural features of the αβtcr mechanotransduction apparatus that promote pmhc discrimination. Front Immunol. 6, 441 (2015).  DOI: 10.3389/fimmu.2015.00441 PMID: 26388869,  PMC4558533.

 

497. S. Imai, P.Kumar, C.U.T. Hellen, V. D’Souza, G.Wagner:  An accurately pre-organized IRES RNA structure enables eIF4G capture for initiating viral translation. Nature Structural and Molecular Biology, 23(9):859-864. doi: 10.1038/nsmb.3280 (2016). PMC5061125

 

498. M.L. Nasr, D. Baptista, M.Strauss, Z.-Y. J. Sun, S. Grigoriu, S. Huser, A. Plückthun,  F. Hagn,, T. Walz,  J. M. Hogle, G. Wagner : Covalently circularized nanodiscs for studying membrane proteins and viral entry, Nature Methods. 2016 Nov 21. doi: 10.1038/nmeth.4079. PMID: 27869813,  PMC5199620

 

499. K. Takeuchi, H. Arthanari, G. Wagner:  Perspective: revisiting the field dependence of TROSY sensitivity. J Biomol NMR. 2016 Dec;66(4):221-225. doi: 10.1007/s10858-016-0075-4. PMC5218892.

 

500.   Z.J. Sun, M.K. Bhanu, M.G. Allan, H.Arthanari, G. Wagner, J. Hanna.   Solution Structure of the Cuz1 AN1 Zinc Finger Domain: An Exposed LDFLP Motif Defines a Subfamily of AN1 Proteins.  PLoS One. 2016 Sep 23;11(9). doi: 10.1371/journal.pone.0163660 PMC5035049

 

501 P. Coote, W. Bermel, G. Wagner, H. Arthanari .  Analytical optimization of active bandwidth and quality factor for TOCSY experiments in NMR spectroscopy. J Biomol NMR. Sep;66(1):9-20 (2016) doi: 10.1007/s10858-016-0051-z  PMC5175489

 

502 Das DK, Mallis RJ, Duke-Cohan JS, Hussey RE, Tetteh PW, Hilton M, Wagner G, Lang MJ, Reinherz EL.  Pre-T Cell Receptors (Pre-TCRs) Leverage Vβ Complementarity Determining Regions (CDRs) and Hydrophobic Patch in Mechanosensing Thymic Self-ligands. J Biol Chem. 2016 Dec 2;291(49):25292-25305. Epub 2016 Oct 5.PMC5207233

 

503. S. Ilic SR Akabayov  H Arthanari G Wagner CC Richardson B Akabayov. Identification of DNA primase inhibitors via a combined fragment-based and virtual screening. Sci Rep. 2016 Nov 2;6:36322. doi: 10.1038/srep36322. PubMed PMID: 27805033; PubMed Central PMCID: PMC5090872.

 

504. C Kozel, B Thompson,  S Hustak, C Moore, A Nakashima,  CR Singh,  M Reid,C Cox, E Papadopoulos, RE  Luna, A Anderson,  H Tagami,  H Hiraishi, EA Slone, KI Yoshino,  M Asano, S Gillaspie, J Nietfeld,   JP Perchellet,  S Rothenburg,  H  Masai,  G Wagner, A Beeser, U Kikkawa, SD Fleming, K.Asano.   Overexpression of eIF5 or its protein mimic 5MP perturbs eIF2 function and induces ATF4 translation through delayed re-initiation. Nucleic Acids Res. 2016 Oct 14;44(18):8704-8713. PMCID: PMC5062967.